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Preliminary study on associated risk factors of mortality due to COVID-19 pandemic in Malaysia

The COVID-19 pandemic has claimed numerous lives worldwide. Malaysia documented about 118 mortalities during the second wave of the outbreak. This study aims to assess associated risk factors of the COVID-19 mortalities from 18 March until 22 May 2020. The majority of patients were above 60 years ol...

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Main Authors:	Mohd Shahrol Abd Wahil, Mohd Hasni Jaafar, Rohaya Ismail, Chua, Su Peng, Chandrika Jeevananthan, Rakesh Singh Sandhu, Mohd Faizal Madrim, Ammar Amsyar Abdul Haddi
Format:	Article
Language:	English
Published:	MDPI 2021
Subjects:	RA643-645 Disease (Communicable and noninfectious) and public health RA648.5-767 Epidemics. Epidemiology. Quarantine. Disinfection
Online Access:	https://eprints.ums.edu.my/id/eprint/42453/1/FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/42453/ https://doi.org/10.3390/ECERPH-3-09022
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spelling	my.ums.eprints.424532024-12-31T01:18:31Z https://eprints.ums.edu.my/id/eprint/42453/ Preliminary study on associated risk factors of mortality due to COVID-19 pandemic in Malaysia Mohd Shahrol Abd Wahil Mohd Hasni Jaafar Rohaya Ismail Chua, Su Peng Chandrika Jeevananthan Rakesh Singh Sandhu Mohd Faizal Madrim Ammar Amsyar Abdul Haddi RA643-645 Disease (Communicable and noninfectious) and public health RA648.5-767 Epidemics. Epidemiology. Quarantine. Disinfection The COVID-19 pandemic has claimed numerous lives worldwide. Malaysia documented about 118 mortalities during the second wave of the outbreak. This study aims to assess associated risk factors of the COVID-19 mortalities from 18 March until 22 May 2020. The majority of patients were above 60 years old (69.0%), male (78.0%), and Malaysian citizens (98.0%). The mean age of the mortalities was 64.01 years old (±SD 14.91 years). The major risk factors consist of hypertension (52.0%), diabetes mellitus (43.0%), cardiovascular diseases (21.0%), extra-pulmonary solid malignancies (5.0%), cerebrovascular diseases (3.0%), pulmonary diseases (1.0%) and pulmonary malignancies (1.0%). About 23.0% of mortalities were related to established clusters while 5.0% had a history of travelling overseas. The mean survival time was 11.87 days (±SD 9.32 days). Approximately 50.0% of the patients survived until day 10 post-admission. The probability of the patients surviving beyond 30 days post-admission was less than 10.0%. There is a significant difference between groups for having a shorter duration to death for risk factors including age group, history of travelling overseas, attending mass gatherings, and having pulmonary malignancies. The hazard ratio (HR) for pulmonary malignancy is 5.512 (95% CI 0.662, 45.899), mass gathering; 3.434 (95% CI 1.375, 8.579), pulmonary disease is 2.442 (95% CI 0.314, 18.983), travelling overseas; 2.251 (95% CI 0.657, 7.711), extra-pulmonary solid malignancy; 2.165 (95% CI 0.767, 6.112), and despite the significant result only applied for mass gathering (p-value = 0.008). COVID-19 screening should be mandatory for those who attend mass gatherings as they are the main source of COVID-19 spread in the community during the second wave outbreak in Malaysia MDPI 2021 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/42453/1/FULL%20TEXT.pdf Mohd Shahrol Abd Wahil and Mohd Hasni Jaafar and Rohaya Ismail and Chua, Su Peng and Chandrika Jeevananthan and Rakesh Singh Sandhu and Mohd Faizal Madrim and Ammar Amsyar Abdul Haddi (2021) Preliminary study on associated risk factors of mortality due to COVID-19 pandemic in Malaysia. Medical Science Forum, 4. pp. 1-15. https://doi.org/10.3390/ECERPH-3-09022
institution	Universiti Malaysia Sabah
building	UMS Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaysia Sabah
content_source	UMS Institutional Repository
url_provider	http://eprints.ums.edu.my/
language	English
topic	RA643-645 Disease (Communicable and noninfectious) and public health RA648.5-767 Epidemics. Epidemiology. Quarantine. Disinfection
spellingShingle	RA643-645 Disease (Communicable and noninfectious) and public health RA648.5-767 Epidemics. Epidemiology. Quarantine. Disinfection Mohd Shahrol Abd Wahil Mohd Hasni Jaafar Rohaya Ismail Chua, Su Peng Chandrika Jeevananthan Rakesh Singh Sandhu Mohd Faizal Madrim Ammar Amsyar Abdul Haddi Preliminary study on associated risk factors of mortality due to COVID-19 pandemic in Malaysia
description	The COVID-19 pandemic has claimed numerous lives worldwide. Malaysia documented about 118 mortalities during the second wave of the outbreak. This study aims to assess associated risk factors of the COVID-19 mortalities from 18 March until 22 May 2020. The majority of patients were above 60 years old (69.0%), male (78.0%), and Malaysian citizens (98.0%). The mean age of the mortalities was 64.01 years old (±SD 14.91 years). The major risk factors consist of hypertension (52.0%), diabetes mellitus (43.0%), cardiovascular diseases (21.0%), extra-pulmonary solid malignancies (5.0%), cerebrovascular diseases (3.0%), pulmonary diseases (1.0%) and pulmonary malignancies (1.0%). About 23.0% of mortalities were related to established clusters while 5.0% had a history of travelling overseas. The mean survival time was 11.87 days (±SD 9.32 days). Approximately 50.0% of the patients survived until day 10 post-admission. The probability of the patients surviving beyond 30 days post-admission was less than 10.0%. There is a significant difference between groups for having a shorter duration to death for risk factors including age group, history of travelling overseas, attending mass gatherings, and having pulmonary malignancies. The hazard ratio (HR) for pulmonary malignancy is 5.512 (95% CI 0.662, 45.899), mass gathering; 3.434 (95% CI 1.375, 8.579), pulmonary disease is 2.442 (95% CI 0.314, 18.983), travelling overseas; 2.251 (95% CI 0.657, 7.711), extra-pulmonary solid malignancy; 2.165 (95% CI 0.767, 6.112), and despite the significant result only applied for mass gathering (p-value = 0.008). COVID-19 screening should be mandatory for those who attend mass gatherings as they are the main source of COVID-19 spread in the community during the second wave outbreak in Malaysia
format	Article
author	Mohd Shahrol Abd Wahil Mohd Hasni Jaafar Rohaya Ismail Chua, Su Peng Chandrika Jeevananthan Rakesh Singh Sandhu Mohd Faizal Madrim Ammar Amsyar Abdul Haddi
author_facet	Mohd Shahrol Abd Wahil Mohd Hasni Jaafar Rohaya Ismail Chua, Su Peng Chandrika Jeevananthan Rakesh Singh Sandhu Mohd Faizal Madrim Ammar Amsyar Abdul Haddi
author_sort	Mohd Shahrol Abd Wahil
title	Preliminary study on associated risk factors of mortality due to COVID-19 pandemic in Malaysia
title_short	Preliminary study on associated risk factors of mortality due to COVID-19 pandemic in Malaysia
title_full	Preliminary study on associated risk factors of mortality due to COVID-19 pandemic in Malaysia
title_fullStr	Preliminary study on associated risk factors of mortality due to COVID-19 pandemic in Malaysia
title_full_unstemmed	Preliminary study on associated risk factors of mortality due to COVID-19 pandemic in Malaysia
title_sort	preliminary study on associated risk factors of mortality due to covid-19 pandemic in malaysia
publisher	MDPI
publishDate	2021
url	https://eprints.ums.edu.my/id/eprint/42453/1/FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/42453/ https://doi.org/10.3390/ECERPH-3-09022
_version_	1821003219507085312
score	13.244109

Preliminary study on associated risk factors of mortality due to COVID-19 pandemic in Malaysia

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