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The antiparasitic potential of senna alata leaves extracts and fractions against marine parasitic leech zeylanicobdella arugamensis

Aquaculture has been a rapidly growing industry in Malaysia, contributing to the country's gross domestic product and enhancing food security and employment opportunities. Among the marine species cultivated in Malaysia are sea bass, snapper, and grouper. Unfortunately, the marine parasitic lee...

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Main Authors: Amanda Oya Jimmy, Venmathi Maran Balu Alagar, Rossita Shapawi, Nurzafirah Mazlan, Muhammad Dawood Shah
Format: Article
Language:English
English
Published: Penerbit UTM Press 2024
Subjects:
SH1-691 Aquaculture. Fisheries. Angling
SH20.3-191 Aquaculture
Online Access:https://eprints.ums.edu.my/id/eprint/42115/1/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/42115/2/FULL%20TEXT.pdf
https://eprints.ums.edu.my/id/eprint/42115/
https://doi.org/10.11113/mjfas.v20n4.3506
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spelling my.ums.eprints.421152024-12-04T07:37:45Z https://eprints.ums.edu.my/id/eprint/42115/ The antiparasitic potential of senna alata leaves extracts and fractions against marine parasitic leech zeylanicobdella arugamensis Amanda Oya Jimmy Venmathi Maran Balu Alagar Rossita Shapawi Nurzafirah Mazlan Muhammad Dawood Shah SH1-691 Aquaculture. Fisheries. Angling SH20.3-191 Aquaculture Aquaculture has been a rapidly growing industry in Malaysia, contributing to the country's gross domestic product and enhancing food security and employment opportunities. Among the marine species cultivated in Malaysia are sea bass, snapper, and grouper. Unfortunately, the marine parasitic leech Zeylanicobdella arugamensis is posing a major threat to a wide variety of cultured marine fish species, including grouper. Various veterinary drugs are used to control parasitic leeches, which are toxic to fish and humans. So, the development of natural treatments from plants is vital. In response to this, Senna alata, also known as the Ringworm bush, was selected. This study aims to evaluate the antiparasitic activity of S. alata methanol extracts, its fractions and water extract against Z. arugamensis. The adult and mature leeches were divided into control and treatment groups. The methanol extract, its fractions (including hexane, chloroform, ethyl acetate, and butanol), and water extracts of S. alata were obtained. Various concentrations (100, 50, 25 and 12.5 mg/ml) of the extracts and fractions were prepared in 5% DMSO and concurrent notation of physico-chemical parameters. Upon exposure, the behaviour and mortality time of the parasitic leeches were recorded. The exposure to the extracts and fractions induced behavioural changes in the parasitic leeches, characterised by aggressive and abnormal swimming patterns coupled with an inability to attach their suction to the surface. Ultimately, complete mortality of parasitic leeches was obtained across extracts and fractions. Overall, the aqueous extract proved to be the most effective, as it displayed the shortest mortality time recorded among the extracts and fractions (2.38±0.15 to 33.08±3.52 minutes). Consequently, the study highlights the antiparasitic potential of the extracts and fractions of S. alata against parasitic leech Z. arugamensis infestation. Penerbit UTM Press 2024 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/42115/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/42115/2/FULL%20TEXT.pdf Amanda Oya Jimmy and Venmathi Maran Balu Alagar and Rossita Shapawi and Nurzafirah Mazlan and Muhammad Dawood Shah (2024) The antiparasitic potential of senna alata leaves extracts and fractions against marine parasitic leech zeylanicobdella arugamensis. Malaysian Journal of Fundamental and Applied Sciences, 20. pp. 1-10. ISSN 2289-5981 https://doi.org/10.11113/mjfas.v20n4.3506
institution Universiti Malaysia Sabah
building UMS Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sabah
content_source UMS Institutional Repository
url_provider http://eprints.ums.edu.my/
language English
English
topic SH1-691 Aquaculture. Fisheries. Angling
SH20.3-191 Aquaculture
spellingShingle SH1-691 Aquaculture. Fisheries. Angling
SH20.3-191 Aquaculture
Amanda Oya Jimmy
Venmathi Maran Balu Alagar
Rossita Shapawi
Nurzafirah Mazlan
Muhammad Dawood Shah
The antiparasitic potential of senna alata leaves extracts and fractions against marine parasitic leech zeylanicobdella arugamensis
description Aquaculture has been a rapidly growing industry in Malaysia, contributing to the country's gross domestic product and enhancing food security and employment opportunities. Among the marine species cultivated in Malaysia are sea bass, snapper, and grouper. Unfortunately, the marine parasitic leech Zeylanicobdella arugamensis is posing a major threat to a wide variety of cultured marine fish species, including grouper. Various veterinary drugs are used to control parasitic leeches, which are toxic to fish and humans. So, the development of natural treatments from plants is vital. In response to this, Senna alata, also known as the Ringworm bush, was selected. This study aims to evaluate the antiparasitic activity of S. alata methanol extracts, its fractions and water extract against Z. arugamensis. The adult and mature leeches were divided into control and treatment groups. The methanol extract, its fractions (including hexane, chloroform, ethyl acetate, and butanol), and water extracts of S. alata were obtained. Various concentrations (100, 50, 25 and 12.5 mg/ml) of the extracts and fractions were prepared in 5% DMSO and concurrent notation of physico-chemical parameters. Upon exposure, the behaviour and mortality time of the parasitic leeches were recorded. The exposure to the extracts and fractions induced behavioural changes in the parasitic leeches, characterised by aggressive and abnormal swimming patterns coupled with an inability to attach their suction to the surface. Ultimately, complete mortality of parasitic leeches was obtained across extracts and fractions. Overall, the aqueous extract proved to be the most effective, as it displayed the shortest mortality time recorded among the extracts and fractions (2.38±0.15 to 33.08±3.52 minutes). Consequently, the study highlights the antiparasitic potential of the extracts and fractions of S. alata against parasitic leech Z. arugamensis infestation.
format Article
author Amanda Oya Jimmy
Venmathi Maran Balu Alagar
Rossita Shapawi
Nurzafirah Mazlan
Muhammad Dawood Shah
author_facet Amanda Oya Jimmy
Venmathi Maran Balu Alagar
Rossita Shapawi
Nurzafirah Mazlan
Muhammad Dawood Shah
author_sort Amanda Oya Jimmy
title The antiparasitic potential of senna alata leaves extracts and fractions against marine parasitic leech zeylanicobdella arugamensis
title_short The antiparasitic potential of senna alata leaves extracts and fractions against marine parasitic leech zeylanicobdella arugamensis
title_full The antiparasitic potential of senna alata leaves extracts and fractions against marine parasitic leech zeylanicobdella arugamensis
title_fullStr The antiparasitic potential of senna alata leaves extracts and fractions against marine parasitic leech zeylanicobdella arugamensis
title_full_unstemmed The antiparasitic potential of senna alata leaves extracts and fractions against marine parasitic leech zeylanicobdella arugamensis
title_sort antiparasitic potential of senna alata leaves extracts and fractions against marine parasitic leech zeylanicobdella arugamensis
publisher Penerbit UTM Press
publishDate 2024
url https://eprints.ums.edu.my/id/eprint/42115/1/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/42115/2/FULL%20TEXT.pdf
https://eprints.ums.edu.my/id/eprint/42115/
https://doi.org/10.11113/mjfas.v20n4.3506
_version_ 1817843858199805952
score 13.223943

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