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Phytochemical Analysis and Antioxidant Activity of Aqueous Extract of Ficus septica Leaves from Sabah, Malaysia

Medicinal plants have long been used as primary antidotes for a variety of ailments, including tuberculosis, heart diseases, cancer, wound healing, asthma, diabetes mellitus, hypertension, pharyngitis, etc. Medicinal plant of Ficus septica Burm. f. (Moraceae) is a subtropical tree commonly known as...

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Main Authors: Senty Vun-Sang, Mohammad Iqbal
Format: Article
Language:English
English
Published: UNIMAS 2023
Subjects:
QH301-705.5 Biology (General)
RS153-441 Materia medica
Online Access:https://eprints.ums.edu.my/id/eprint/38649/1/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/38649/2/FULL%20TEXT.pdf
https://eprints.ums.edu.my/id/eprint/38649/
https://doi.org/10.33736/bjrst.5591.2023
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spelling my.ums.eprints.386492024-05-13T07:18:33Z https://eprints.ums.edu.my/id/eprint/38649/ Phytochemical Analysis and Antioxidant Activity of Aqueous Extract of Ficus septica Leaves from Sabah, Malaysia Senty Vun-Sang Mohammad Iqbal QH301-705.5 Biology (General) RS153-441 Materia medica Medicinal plants have long been used as primary antidotes for a variety of ailments, including tuberculosis, heart diseases, cancer, wound healing, asthma, diabetes mellitus, hypertension, pharyngitis, etc. Medicinal plant of Ficus septica Burm. f. (Moraceae) is a subtropical tree commonly known as the ivory fig, septic fig or white-veined fig. The present work aims to investigate the antioxidant activity, phenolic and flavonoid content, and qualitative screening of various phytochemicals in aqueous extracts of F. septica leaves. Total phenol and flavonoid contents were calculated using Folin-Ciocalteau and aluminium chloride reagents. The antioxidative effect of F. septica was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay. Ficus septica was found to contain 27.32 ± 0.03 mg/g total phenolics expressed as gallic acid equivalent and 12.65 ± 0.00 mg/g total flavonoid expressed as catechin equivalent. In addition, the leaf extracts were found to contain various secondary metabolites such as alkaloids, flavonoids, tannins, saponins, steroids and triterpenoids. The ability of F. septica to scavenge the DPPH radical was determined by its IC50 value. The IC50 value of F. septica was 4.45 µg/mL. Inferred from the presence of phytochemicals, total phenolic and flavonoid content, and antioxidant activity of the plant, F. septica could be a potential addition to pharmaceutical products to improve human health by participating in the antioxidant defence system against the production of free radicals. UNIMAS 2023 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/38649/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/38649/2/FULL%20TEXT.pdf Senty Vun-Sang and Mohammad Iqbal (2023) Phytochemical Analysis and Antioxidant Activity of Aqueous Extract of Ficus septica Leaves from Sabah, Malaysia. Borneo Journal of Resource Science and Technology, 13 (2). pp. 67-78. ISSN 2229-9769 https://doi.org/10.33736/bjrst.5591.2023
institution Universiti Malaysia Sabah
building UMS Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sabah
content_source UMS Institutional Repository
url_provider http://eprints.ums.edu.my/
language English
English
topic QH301-705.5 Biology (General)
RS153-441 Materia medica
spellingShingle QH301-705.5 Biology (General)
RS153-441 Materia medica
Senty Vun-Sang
Mohammad Iqbal
Phytochemical Analysis and Antioxidant Activity of Aqueous Extract of Ficus septica Leaves from Sabah, Malaysia
description Medicinal plants have long been used as primary antidotes for a variety of ailments, including tuberculosis, heart diseases, cancer, wound healing, asthma, diabetes mellitus, hypertension, pharyngitis, etc. Medicinal plant of Ficus septica Burm. f. (Moraceae) is a subtropical tree commonly known as the ivory fig, septic fig or white-veined fig. The present work aims to investigate the antioxidant activity, phenolic and flavonoid content, and qualitative screening of various phytochemicals in aqueous extracts of F. septica leaves. Total phenol and flavonoid contents were calculated using Folin-Ciocalteau and aluminium chloride reagents. The antioxidative effect of F. septica was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay. Ficus septica was found to contain 27.32 ± 0.03 mg/g total phenolics expressed as gallic acid equivalent and 12.65 ± 0.00 mg/g total flavonoid expressed as catechin equivalent. In addition, the leaf extracts were found to contain various secondary metabolites such as alkaloids, flavonoids, tannins, saponins, steroids and triterpenoids. The ability of F. septica to scavenge the DPPH radical was determined by its IC50 value. The IC50 value of F. septica was 4.45 µg/mL. Inferred from the presence of phytochemicals, total phenolic and flavonoid content, and antioxidant activity of the plant, F. septica could be a potential addition to pharmaceutical products to improve human health by participating in the antioxidant defence system against the production of free radicals.
format Article
author Senty Vun-Sang
Mohammad Iqbal
author_facet Senty Vun-Sang
Mohammad Iqbal
author_sort Senty Vun-Sang
title Phytochemical Analysis and Antioxidant Activity of Aqueous Extract of Ficus septica Leaves from Sabah, Malaysia
title_short Phytochemical Analysis and Antioxidant Activity of Aqueous Extract of Ficus septica Leaves from Sabah, Malaysia
title_full Phytochemical Analysis and Antioxidant Activity of Aqueous Extract of Ficus septica Leaves from Sabah, Malaysia
title_fullStr Phytochemical Analysis and Antioxidant Activity of Aqueous Extract of Ficus septica Leaves from Sabah, Malaysia
title_full_unstemmed Phytochemical Analysis and Antioxidant Activity of Aqueous Extract of Ficus septica Leaves from Sabah, Malaysia
title_sort phytochemical analysis and antioxidant activity of aqueous extract of ficus septica leaves from sabah, malaysia
publisher UNIMAS
publishDate 2023
url https://eprints.ums.edu.my/id/eprint/38649/1/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/38649/2/FULL%20TEXT.pdf
https://eprints.ums.edu.my/id/eprint/38649/
https://doi.org/10.33736/bjrst.5591.2023
_version_ 1800089055349702656
score 13.211869

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