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Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study

Background: Hypothyroidism is the most common pathophysiological condition that affects mostly females in both developed and developing countries. Data on hypothyroidism among adult females are essential to understand the underactive status of the thyroid gland among the female population and its co...

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Main Authors: Sadia Choudhury Shimmi, Hossameldin Fatthy Eldosouky, M. Tanveer Hossain Parash, Wan Salman Wan Saudi
Format: Article
Language:English
English
Published: National Library of Medicine 2023
Subjects:
RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens
RC648-665 Diseases of the endocrine glands. Clinical endocrinology
Online Access:https://eprints.ums.edu.my/id/eprint/36819/1/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/36819/2/FULL%20TEXT.pdf
https://eprints.ums.edu.my/id/eprint/36819/
https://doi.org/10.7759/cureus.37152
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spelling my.ums.eprints.368192023-09-19T01:58:40Z https://eprints.ums.edu.my/id/eprint/36819/ Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study Sadia Choudhury Shimmi Hossameldin Fatthy Eldosouky M. Tanveer Hossain Parash Wan Salman Wan Saudi RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens RC648-665 Diseases of the endocrine glands. Clinical endocrinology Background: Hypothyroidism is the most common pathophysiological condition that affects mostly females in both developed and developing countries. Data on hypothyroidism among adult females are essential to understand the underactive status of the thyroid gland among the female population and its correlated effects on a deficiency of vitamin D and iron, as effective prevention of osteoporotic changes and iron deficiency anemia is possible. Therefore, the present study was designed to investigate the probability of concurrent iron and vitamin D deficiency among the adult hypothyroid female population of Abu Dhabi, UAE. Materials and methods: This cross-sectional study was carried out from September 2019 to July 2021 among 500 adult females aged 18 to 45 years old in Sheikh Shakhbout Medical City (SSMC) and Sheikh Khalifa Medical City (SKMC), Abu Dhabi, UAE. After obtaining written informed consent, subjects' demographic characteristics (sun exposure, dressing code, food consumption), anthropometry (height, weight, BMI), and biochemical parameters (thyroid profile, vitamin D profile, iron profile, and blood indices) were measured. Results: In this study, serum vitamin D and iron levels were significantly (p<0.01) decreased in the hypothyroid female group (study group). The serum vitamin D and iron levels showed a significant negative (p<0.01) correlation with thyroid-stimulating hormone (TSH). Out of 250 study group participants, 61 had a concurrent deficiency of serum vitamin D and iron, yielding a probability (P of low vitamin D and iron and hypothyroidism) of 0.244, which indicates that if 1000 hypothyroid patients are tested for serum vitamin D and iron levels, 24 patients are probable to have low vitamin D and iron. Conclusion: The study concluded that vitamin D and iron bi-deficiency were observed in adult hypothyroid females in Abu Dhabi, UAE. So, the routine check-up of thyroid function and vitamin D and iron profiles should be done early. Therefore, early vitamin D and iron deficiencies can be detected, and supplements can be given to prevent further health complications like osteoporosis and iron deficiency anemia. National Library of Medicine 2023 Article NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/36819/1/ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/36819/2/FULL%20TEXT.pdf Sadia Choudhury Shimmi and Hossameldin Fatthy Eldosouky and M. Tanveer Hossain Parash and Wan Salman Wan Saudi (2023) Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study. Cureus, 15 (4). pp. 1-12. https://doi.org/10.7759/cureus.37152
institution Universiti Malaysia Sabah
building UMS Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sabah
content_source UMS Institutional Repository
url_provider http://eprints.ums.edu.my/
language English
English
topic RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens
RC648-665 Diseases of the endocrine glands. Clinical endocrinology
spellingShingle RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens
RC648-665 Diseases of the endocrine glands. Clinical endocrinology
Sadia Choudhury Shimmi
Hossameldin Fatthy Eldosouky
M. Tanveer Hossain Parash
Wan Salman Wan Saudi
Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study
description Background: Hypothyroidism is the most common pathophysiological condition that affects mostly females in both developed and developing countries. Data on hypothyroidism among adult females are essential to understand the underactive status of the thyroid gland among the female population and its correlated effects on a deficiency of vitamin D and iron, as effective prevention of osteoporotic changes and iron deficiency anemia is possible. Therefore, the present study was designed to investigate the probability of concurrent iron and vitamin D deficiency among the adult hypothyroid female population of Abu Dhabi, UAE. Materials and methods: This cross-sectional study was carried out from September 2019 to July 2021 among 500 adult females aged 18 to 45 years old in Sheikh Shakhbout Medical City (SSMC) and Sheikh Khalifa Medical City (SKMC), Abu Dhabi, UAE. After obtaining written informed consent, subjects' demographic characteristics (sun exposure, dressing code, food consumption), anthropometry (height, weight, BMI), and biochemical parameters (thyroid profile, vitamin D profile, iron profile, and blood indices) were measured. Results: In this study, serum vitamin D and iron levels were significantly (p<0.01) decreased in the hypothyroid female group (study group). The serum vitamin D and iron levels showed a significant negative (p<0.01) correlation with thyroid-stimulating hormone (TSH). Out of 250 study group participants, 61 had a concurrent deficiency of serum vitamin D and iron, yielding a probability (P of low vitamin D and iron and hypothyroidism) of 0.244, which indicates that if 1000 hypothyroid patients are tested for serum vitamin D and iron levels, 24 patients are probable to have low vitamin D and iron. Conclusion: The study concluded that vitamin D and iron bi-deficiency were observed in adult hypothyroid females in Abu Dhabi, UAE. So, the routine check-up of thyroid function and vitamin D and iron profiles should be done early. Therefore, early vitamin D and iron deficiencies can be detected, and supplements can be given to prevent further health complications like osteoporosis and iron deficiency anemia.
format Article
author Sadia Choudhury Shimmi
Hossameldin Fatthy Eldosouky
M. Tanveer Hossain Parash
Wan Salman Wan Saudi
author_facet Sadia Choudhury Shimmi
Hossameldin Fatthy Eldosouky
M. Tanveer Hossain Parash
Wan Salman Wan Saudi
author_sort Sadia Choudhury Shimmi
title Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study
title_short Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study
title_full Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study
title_fullStr Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study
title_full_unstemmed Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study
title_sort probability of concurrent deficiency of vitamin d and iron in hypothyroidism: a cross-sectional study
publisher National Library of Medicine
publishDate 2023
url https://eprints.ums.edu.my/id/eprint/36819/1/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/36819/2/FULL%20TEXT.pdf
https://eprints.ums.edu.my/id/eprint/36819/
https://doi.org/10.7759/cureus.37152
_version_ 1778162802191499264
score 13.211869

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