Catalytic Properties of Caseinolytic Protease Subunit of Plasmodium knowlesi and Its Inhibition by a Member of δ-Lactone, Hyptolide

The caseinolytic protease (Clp) system plays an essential role in the protein homeostasis of the malaria parasite, particularly at the stage of apicoplast development. The inhibition of this protein is known to have a lethal effect on the parasite and is therefore considered an interesting avenue fo...

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Bibliographic Details
Main Authors: Cahyo Budiman, Raimalynah Abd Razak, Angelesa Runin Unggit, Rafida Razali, Meiny Suzery, Ruzaidi Azli Mohd Mokhtar, Lee, Ping Chin, Didik Huswo Utomo
Format: Article
Language:English
English
Published: Multidisciplinary Digital Publishing Institute (MDPI) 2022
Subjects:
Online Access:https://eprints.ums.edu.my/id/eprint/33185/5/Catalytic%20Properties%20of%20Caseinolytic%20Protease%20Subunit%20of%20Plasmodium%20knowlesi%20and%20Its%20Inhibition%20by%20a%20Member%20of%20%CE%B4-Lactone%2C%20Hyptolide.pdf
https://eprints.ums.edu.my/id/eprint/33185/3/Catalytic%20Properties%20of%20Caseinolytic%20Protease%20Subunit%20of%20Plasmodium%20knowlesi%20and%20Its%20Inhibition%20by%20a%20Member%20of%20%CE%B4-Lactone%2C%20Hyptolide%20_ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/33185/
https://www.mdpi.com/1420-3049/27/12/3787/htm
https://doi.org/10.3390/molecules27123787
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