Staff View: Hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism: an uncommon cause of acute muscle paralysis

Hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism: an uncommon cause of acute muscle paralysis

Hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism is an uncommon clinical phenomenon characterised by lower limb paralysis secondary to hypokalaemia in the background of subclinical hyperthyroidism. In this article, we report a patient who presented with progressive lower limb...

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Main Authors:	Alvin Oliver Payus, Constance Liew Sat Lin, Nee Tiong, Norlaila Mustafa
Format:	Article
Language:	English English
Published:	BMJ Publishing Group 2021
Subjects:	QM531-549 Regional anatomy RC648-665 Diseases of the endocrine glands. Clinical endocrinology
Online Access:	https://eprints.ums.edu.my/id/eprint/30740/1/Hypokalaemic%20periodic%20paralysis%20secondary%20to%20subclinical%20hyperthyroidism%2C%20an%20uncommon%20cause%20of%20acute%20muscle%20paralysis-ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/30740/2/Hypokalaemic%20periodic%20paralysis%20secondary%20to%20subclinical%20hyperthyroidism%2C%20an%20uncommon%20cause%20of%20acute%20muscle%20paralysis.pdf https://eprints.ums.edu.my/id/eprint/30740/ https://casereports.bmj.com/content/14/6/e240666
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spelling	my.ums.eprints.307402021-10-26T08:08:06Z https://eprints.ums.edu.my/id/eprint/30740/ Hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism: an uncommon cause of acute muscle paralysis Alvin Oliver Payus Constance Liew Sat Lin Nee Tiong Norlaila Mustafa QM531-549 Regional anatomy RC648-665 Diseases of the endocrine glands. Clinical endocrinology Hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism is an uncommon clinical phenomenon characterised by lower limb paralysis secondary to hypokalaemia in the background of subclinical hyperthyroidism. In this article, we report a patient who presented with progressive lower limb muscle weakness secondary to hypokalaemia that was refractory to potassium replacement therapy. He has no diarrhoea, no reduced appetite and was not taking any medication that can cause potassium wasting. Although he was clinically euthyroid, his thyroid function test revealed subclinical hyperthyroidism. His 24-hour urine potassium level was normal, which makes a rapid transcellular shift of potassium secondary to subclinical hyperthyroidism as the possible cause. He was successfully treated with potassium supplements, non-selective beta-blockers and anti-thyroid medication. This case report aimed to share an uncommon case of hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism, which to our knowledge, only a few has been reported in the literature. BMJ Publishing Group 2021-06-24 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/30740/1/Hypokalaemic%20periodic%20paralysis%20secondary%20to%20subclinical%20hyperthyroidism%2C%20an%20uncommon%20cause%20of%20acute%20muscle%20paralysis-ABSTRACT.pdf text en https://eprints.ums.edu.my/id/eprint/30740/2/Hypokalaemic%20periodic%20paralysis%20secondary%20to%20subclinical%20hyperthyroidism%2C%20an%20uncommon%20cause%20of%20acute%20muscle%20paralysis.pdf Alvin Oliver Payus and Constance Liew Sat Lin and Nee Tiong and Norlaila Mustafa (2021) Hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism: an uncommon cause of acute muscle paralysis. BMJ Case Reports, 14. pp. 1-4. ISSN 1757-790X https://casereports.bmj.com/content/14/6/e240666 ttp://dx.doi.org/10.1136/bcr-2020- 240666
institution	Universiti Malaysia Sabah
building	UMS Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaysia Sabah
content_source	UMS Institutional Repository
url_provider	http://eprints.ums.edu.my/
language	English English
topic	QM531-549 Regional anatomy RC648-665 Diseases of the endocrine glands. Clinical endocrinology
spellingShingle	QM531-549 Regional anatomy RC648-665 Diseases of the endocrine glands. Clinical endocrinology Alvin Oliver Payus Constance Liew Sat Lin Nee Tiong Norlaila Mustafa Hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism: an uncommon cause of acute muscle paralysis
description	Hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism is an uncommon clinical phenomenon characterised by lower limb paralysis secondary to hypokalaemia in the background of subclinical hyperthyroidism. In this article, we report a patient who presented with progressive lower limb muscle weakness secondary to hypokalaemia that was refractory to potassium replacement therapy. He has no diarrhoea, no reduced appetite and was not taking any medication that can cause potassium wasting. Although he was clinically euthyroid, his thyroid function test revealed subclinical hyperthyroidism. His 24-hour urine potassium level was normal, which makes a rapid transcellular shift of potassium secondary to subclinical hyperthyroidism as the possible cause. He was successfully treated with potassium supplements, non-selective beta-blockers and anti-thyroid medication. This case report aimed to share an uncommon case of hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism, which to our knowledge, only a few has been reported in the literature.
format	Article
author	Alvin Oliver Payus Constance Liew Sat Lin Nee Tiong Norlaila Mustafa
author_facet	Alvin Oliver Payus Constance Liew Sat Lin Nee Tiong Norlaila Mustafa
author_sort	Alvin Oliver Payus
title	Hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism: an uncommon cause of acute muscle paralysis
title_short	Hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism: an uncommon cause of acute muscle paralysis
title_full	Hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism: an uncommon cause of acute muscle paralysis
title_fullStr	Hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism: an uncommon cause of acute muscle paralysis
title_full_unstemmed	Hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism: an uncommon cause of acute muscle paralysis
title_sort	hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism: an uncommon cause of acute muscle paralysis
publisher	BMJ Publishing Group
publishDate	2021
url	https://eprints.ums.edu.my/id/eprint/30740/1/Hypokalaemic%20periodic%20paralysis%20secondary%20to%20subclinical%20hyperthyroidism%2C%20an%20uncommon%20cause%20of%20acute%20muscle%20paralysis-ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/30740/2/Hypokalaemic%20periodic%20paralysis%20secondary%20to%20subclinical%20hyperthyroidism%2C%20an%20uncommon%20cause%20of%20acute%20muscle%20paralysis.pdf https://eprints.ums.edu.my/id/eprint/30740/ https://casereports.bmj.com/content/14/6/e240666
_version_	1760230804340867072
score	13.211869

Hypokalaemic periodic paralysis secondary to subclinical hyperthyroidism: an uncommon cause of acute muscle paralysis

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