Prospective diagnostic study on the use of narrow‐band imaging on suspicious lesions during colonoscopy examination
Introduction: Colonoscopy is the gold standard to detect colorectal neoplasm. Narrow-band imaging (NBI) has a good diagnostic accuracy to differentiate between neoplastic and non-neoplastic colorectal lesions. This study explores the diagnostic validity of NBI colonoscopy as well as its associated f...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
Wiley Blackwell
2018
|
| Subjects: | |
| Online Access: | https://eprints.ums.edu.my/id/eprint/28961/3/FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/28961/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/28961/ https://onlinelibrary.wiley.com/doi/full/10.1111/ases.12463 https://doi.org/10.1111/ases.12463 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
my.ums.eprints.28961 |
|---|---|
| record_format |
eprints |
| spelling |
my.ums.eprints.289612022-10-11T04:33:24Z https://eprints.ums.edu.my/id/eprint/28961/ Prospective diagnostic study on the use of narrow‐band imaging on suspicious lesions during colonoscopy examination Huzairi Yaacob Sani Mohamad Ikhwan Mohd Nizam Hashim Syed Hassan Syed Abd Aziz Wan Zainira Wan Zain Sharifah Emilia Tuan Sharif Mohd Firdaus Mohd Hayati Andee Dzulkarnaen Zakaria RC799-869 Diseases of the digestive system. Gastroenterology Introduction: Colonoscopy is the gold standard to detect colorectal neoplasm. Narrow-band imaging (NBI) has a good diagnostic accuracy to differentiate between neoplastic and non-neoplastic colorectal lesions. This study explores the diagnostic validity of NBI colonoscopy as well as its associated factors related to neoplastic and non-neoplastic colorectal lesions. Methods: This study enrolled 100 patients in a single-center tertiary teaching hospital. Patients presented for screening colonoscopy, and those with suspicious colorectal lesions were included in this study. During colonoscopy, the most suspicious lesion in each patient was analyzed using the NBI system based on Sano’s classification. Each lesion was biopsied for histopathological analysis, the gold standard. Endoscopic images were captured electronically. The sensitivity, specificity, and diagnostic accuracy of NBI colonoscopy were assessed. Other associated factors related to neoplastic and non-neoplastic lesions were analyzed accordingly. Results: The sensitivity and specificity of the NBI were 88.2% and 71.9%, respectively. The area under the receiver–operator curve was 0.801, indicating that NBI has a good ability to differentiate between disease and non-disease. There are significant associations between histopathological examination outcomes and both presenting symptoms, especially weight loss, and lesion site, even after other variables were controlled (P < 0.05). Conclusion: The NBI system in colonoscopy was capable of distinguishing neoplastic from non-neoplastic colorectal lesions. It indicates an acceptable level of agreement with histopathology, the gold standard. However, the role of NBI in screening and surveillance in Malaysia still needs further evaluation and exploration. Wiley Blackwell 2018 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/28961/3/FULL%20TEXT.pdf text en https://eprints.ums.edu.my/id/eprint/28961/1/ABSTRACT.pdf Huzairi Yaacob and Sani Mohamad Ikhwan and Mohd Nizam Hashim and Syed Hassan Syed Abd Aziz and Wan Zainira Wan Zain and Sharifah Emilia Tuan Sharif and Mohd Firdaus Mohd Hayati and Andee Dzulkarnaen Zakaria (2018) Prospective diagnostic study on the use of narrow‐band imaging on suspicious lesions during colonoscopy examination. Asian Journal of Endoscopic Surgery, 11. pp. 318-324. ISSN 1758-5902 (P-ISSN) , 1758-5910 (E-ISSN) https://onlinelibrary.wiley.com/doi/full/10.1111/ases.12463 https://doi.org/10.1111/ases.12463 |
| institution |
Universiti Malaysia Sabah |
| building |
UMS Library |
| collection |
Institutional Repository |
| continent |
Asia |
| country |
Malaysia |
| content_provider |
Universiti Malaysia Sabah |
| content_source |
UMS Institutional Repository |
| url_provider |
http://eprints.ums.edu.my/ |
| language |
English English |
| topic |
RC799-869 Diseases of the digestive system. Gastroenterology |
| spellingShingle |
RC799-869 Diseases of the digestive system. Gastroenterology Huzairi Yaacob Sani Mohamad Ikhwan Mohd Nizam Hashim Syed Hassan Syed Abd Aziz Wan Zainira Wan Zain Sharifah Emilia Tuan Sharif Mohd Firdaus Mohd Hayati Andee Dzulkarnaen Zakaria Prospective diagnostic study on the use of narrow‐band imaging on suspicious lesions during colonoscopy examination |
| description |
Introduction: Colonoscopy is the gold standard to detect colorectal neoplasm. Narrow-band imaging (NBI) has a good diagnostic accuracy to differentiate between neoplastic and non-neoplastic colorectal lesions. This study explores the diagnostic validity of NBI colonoscopy as well as its associated factors related to neoplastic and non-neoplastic colorectal lesions. Methods: This study enrolled 100 patients in a single-center tertiary teaching hospital. Patients presented for screening colonoscopy, and those with suspicious colorectal lesions were included in this study. During colonoscopy, the most suspicious lesion in each patient was analyzed using the NBI system based on Sano’s classification. Each lesion was biopsied for histopathological analysis, the gold standard. Endoscopic images were captured electronically. The sensitivity, specificity, and diagnostic accuracy of NBI colonoscopy were assessed. Other associated factors related to neoplastic and non-neoplastic lesions were analyzed accordingly. Results: The sensitivity and specificity of the NBI were 88.2% and 71.9%, respectively. The area under the receiver–operator curve was 0.801, indicating that NBI has a good ability to differentiate between disease and non-disease. There are significant associations between histopathological examination outcomes and both presenting symptoms, especially weight loss, and lesion site, even after other variables were controlled (P < 0.05). Conclusion: The NBI system in colonoscopy was capable of distinguishing neoplastic from non-neoplastic colorectal lesions. It indicates an acceptable level of agreement with histopathology, the gold standard. However, the role of NBI in screening and surveillance in Malaysia still needs further evaluation and exploration. |
| format |
Article |
| author |
Huzairi Yaacob Sani Mohamad Ikhwan Mohd Nizam Hashim Syed Hassan Syed Abd Aziz Wan Zainira Wan Zain Sharifah Emilia Tuan Sharif Mohd Firdaus Mohd Hayati Andee Dzulkarnaen Zakaria |
| author_facet |
Huzairi Yaacob Sani Mohamad Ikhwan Mohd Nizam Hashim Syed Hassan Syed Abd Aziz Wan Zainira Wan Zain Sharifah Emilia Tuan Sharif Mohd Firdaus Mohd Hayati Andee Dzulkarnaen Zakaria |
| author_sort |
Huzairi Yaacob |
| title |
Prospective diagnostic study on the use of narrow‐band imaging on suspicious lesions during colonoscopy examination |
| title_short |
Prospective diagnostic study on the use of narrow‐band imaging on suspicious lesions during colonoscopy examination |
| title_full |
Prospective diagnostic study on the use of narrow‐band imaging on suspicious lesions during colonoscopy examination |
| title_fullStr |
Prospective diagnostic study on the use of narrow‐band imaging on suspicious lesions during colonoscopy examination |
| title_full_unstemmed |
Prospective diagnostic study on the use of narrow‐band imaging on suspicious lesions during colonoscopy examination |
| title_sort |
prospective diagnostic study on the use of narrow‐band imaging on suspicious lesions during colonoscopy examination |
| publisher |
Wiley Blackwell |
| publishDate |
2018 |
| url |
https://eprints.ums.edu.my/id/eprint/28961/3/FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/28961/1/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/28961/ https://onlinelibrary.wiley.com/doi/full/10.1111/ases.12463 https://doi.org/10.1111/ases.12463 |
| _version_ |
1760230656877527040 |
| score |
13.211869 |