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Phytochemical investigation and antioxidant activity of ganoderma boninense

Ganoderma lucidum is known as a functional mushroom and is traditionally being used as medicine but G. boninense is well known as the causal pathogen of basal stem rot disease of oil palm. Numerous secondary metabolites of mushrooms from this genus have been reported with various biological activiti...

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Main Authors: Yow, San Chan, Khim Phin Chong, Khim Phin
Format: Article
Language:English
English
Published: Universiti Malaya 2020
Subjects:
QD Chemistry
Online Access:https://eprints.ums.edu.my/id/eprint/27508/1/Phytochemical%20investigation%20and%20antioxidant%20activity%20of%20ganoderma%20boninense%20abstract.pdf
https://eprints.ums.edu.my/id/eprint/27508/2/Phytochemical%20investigation%20and%20antioxidant%20activity%20of%20ganoderma%20boninense%20fulltext.pdf
https://eprints.ums.edu.my/id/eprint/27508/
https://1f169227-0328-4af2-99bc-24934f131be8.filesusr.com/ugd/66925b_40d88ce427f2403bb4db108d04c3ab7d.pdf
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spelling my.ums.eprints.275082021-06-30T11:03:14Z https://eprints.ums.edu.my/id/eprint/27508/ Phytochemical investigation and antioxidant activity of ganoderma boninense Yow, San Chan Khim Phin Chong, Khim Phin QD Chemistry Ganoderma lucidum is known as a functional mushroom and is traditionally being used as medicine but G. boninense is well known as the causal pathogen of basal stem rot disease of oil palm. Numerous secondary metabolites of mushrooms from this genus have been reported with various biological activities. However, there are not many report on the medicinal benefits of G. boninense. Hence, this study was designed to investigate the phytochemical constituents and antioxidant activities of the fruiting body G. boninense extracts. Various groups of phytochemicals were extracted using solvents with different polarities such as chloroform, ethyl acetate, acetone, methanol, ethanol and distilled water. Results confirmed the presence of numerous phytochemicals in G. boninense fruiting body. Ethanolic extract of G. boninense has the highest phenolic (33.05 ± 1.374 mg GAE/g DW) and total flavonoid (8.20 ± 0.059 mg QE/g DW) content. Furthermore, ethanolic extract of G. boninense also exhibited the greatest potency in antiradical activity with IC50 of 113.9 ± 2.78 µg/ml. Correlation coefficient, R2 = 0.97 suggested phenolic acids of ethanol extract was contributed to its radical scavenging activity. Universiti Malaya 2020 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/27508/1/Phytochemical%20investigation%20and%20antioxidant%20activity%20of%20ganoderma%20boninense%20abstract.pdf text en https://eprints.ums.edu.my/id/eprint/27508/2/Phytochemical%20investigation%20and%20antioxidant%20activity%20of%20ganoderma%20boninense%20fulltext.pdf Yow, San Chan and Khim Phin Chong, Khim Phin (2020) Phytochemical investigation and antioxidant activity of ganoderma boninense. Malaysian Journal of Biochemistry and Molecular Biology, 3. 138- 149. ISSN 1511-2616 https://1f169227-0328-4af2-99bc-24934f131be8.filesusr.com/ugd/66925b_40d88ce427f2403bb4db108d04c3ab7d.pdf
institution Universiti Malaysia Sabah
building UMS Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sabah
content_source UMS Institutional Repository
url_provider http://eprints.ums.edu.my/
language English
English
topic QD Chemistry
spellingShingle QD Chemistry
Yow, San Chan
Khim Phin Chong, Khim Phin
Phytochemical investigation and antioxidant activity of ganoderma boninense
description Ganoderma lucidum is known as a functional mushroom and is traditionally being used as medicine but G. boninense is well known as the causal pathogen of basal stem rot disease of oil palm. Numerous secondary metabolites of mushrooms from this genus have been reported with various biological activities. However, there are not many report on the medicinal benefits of G. boninense. Hence, this study was designed to investigate the phytochemical constituents and antioxidant activities of the fruiting body G. boninense extracts. Various groups of phytochemicals were extracted using solvents with different polarities such as chloroform, ethyl acetate, acetone, methanol, ethanol and distilled water. Results confirmed the presence of numerous phytochemicals in G. boninense fruiting body. Ethanolic extract of G. boninense has the highest phenolic (33.05 ± 1.374 mg GAE/g DW) and total flavonoid (8.20 ± 0.059 mg QE/g DW) content. Furthermore, ethanolic extract of G. boninense also exhibited the greatest potency in antiradical activity with IC50 of 113.9 ± 2.78 µg/ml. Correlation coefficient, R2 = 0.97 suggested phenolic acids of ethanol extract was contributed to its radical scavenging activity.
format Article
author Yow, San Chan
Khim Phin Chong, Khim Phin
author_facet Yow, San Chan
Khim Phin Chong, Khim Phin
author_sort Yow, San Chan
title Phytochemical investigation and antioxidant activity of ganoderma boninense
title_short Phytochemical investigation and antioxidant activity of ganoderma boninense
title_full Phytochemical investigation and antioxidant activity of ganoderma boninense
title_fullStr Phytochemical investigation and antioxidant activity of ganoderma boninense
title_full_unstemmed Phytochemical investigation and antioxidant activity of ganoderma boninense
title_sort phytochemical investigation and antioxidant activity of ganoderma boninense
publisher Universiti Malaya
publishDate 2020
url https://eprints.ums.edu.my/id/eprint/27508/1/Phytochemical%20investigation%20and%20antioxidant%20activity%20of%20ganoderma%20boninense%20abstract.pdf
https://eprints.ums.edu.my/id/eprint/27508/2/Phytochemical%20investigation%20and%20antioxidant%20activity%20of%20ganoderma%20boninense%20fulltext.pdf
https://eprints.ums.edu.my/id/eprint/27508/
https://1f169227-0328-4af2-99bc-24934f131be8.filesusr.com/ugd/66925b_40d88ce427f2403bb4db108d04c3ab7d.pdf
_version_ 1760230630632718336
score 13.211869

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