Aaptamine-related alkaloid from the marine sponge Aaptos aaptos
A new aaptamine-related alkaloid, 1,3-dioxolo [4,5-d] benzo [de]-1,6-naphthyridine (methylenedioxyaaptamine, 1), was isolated from the organic extracts of the Bornean marine sponge Aaptos aaptos, together with a known aaptamine derivative, 8,9,9-trimethoxy-9H-benzo [de]-1,6-naphthyridine (2). The st...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
2019
|
| Subjects: | |
| Online Access: | https://eprints.ums.edu.my/id/eprint/25475/1/Aaptamine-related%20alkaloid%20from%20the%20marine%20sponge%20Aaptos%20aaptos.pdf https://eprints.ums.edu.my/id/eprint/25475/2/Aaptamine-related%20alkaloid%20from%20the%20marine%20sponge%20Aaptos%20aaptos%201.pdf https://eprints.ums.edu.my/id/eprint/25475/ https://doi.org/10.1177/1934578X19863935 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | A new aaptamine-related alkaloid, 1,3-dioxolo [4,5-d] benzo [de]-1,6-naphthyridine (methylenedioxyaaptamine, 1), was isolated from the organic extracts of the Bornean marine sponge Aaptos aaptos, together with a known aaptamine derivative, 8,9,9-trimethoxy-9H-benzo [de]-1,6-naphthyridine (2). The structure of compound 1 was elucidated by interpretation of its spectroscopic data. Two compounds were tested for their cytotoxic potentials against adult T-cell leukemia (ATL) cells, and compound 1 showed moderate cytotoxic potential. |
|---|