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Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet

Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts were a...

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Main Authors: Tasnuva Sarwar Tunna, Sarker, Md Zaidul Islam, Ghafoor, Kashif, Ferdosh, Sahena, Jaffri, Juliana Md, Al-Juhaimi, Fahad Y, Selamat, Jinap, Ali, Md Eaqub, Md Jahurul Haque Akanda, Awal, Md Shihabul, Ahmed, Qamar Uddin
Format: Article
Language:English
Published: 2017
Subjects:
QK Botany
Online Access:https://eprints.ums.edu.my/id/eprint/23697/1/Enrichmentin%20vitro%2C%20and%20quantification%20study%20of%20antidiabetic%20compounds%20from%20neglected%20weed%20Mimosa%20pudica%20using%20supercritical%20CO2%20and%20CO2-Soxhlet.pdf
https://eprints.ums.edu.my/id/eprint/23697/
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spelling my.ums.eprints.236972019-10-01T06:27:30Z https://eprints.ums.edu.my/id/eprint/23697/ Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet Tasnuva Sarwar Tunna Sarker, Md Zaidul Islam Ghafoor, Kashif Ferdosh, Sahena Jaffri, Juliana Md Al-Juhaimi, Fahad Y Selamat, Jinap Ali, Md Eaqub Md Jahurul Haque Akanda Awal, Md Shihabul Ahmed, Qamar Uddin QK Botany Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts were analyzed pharmacologically, qualitatively and quantitatively to ascertain enrichment levels. All three antidiabetic compounds were effectively enriched under optimized conditions of temperature 60°C, pressure 40 MPa, co-solvent ratio 30%, and CO2 flow rate of 5 ml min−1. SFE was found to be the better method for enrichment of the antidiabetic compounds than the CO2-Soxhlet method. Extraction conditions were seen to affect the enrichment of desired compounds. 2017-03-04 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/23697/1/Enrichmentin%20vitro%2C%20and%20quantification%20study%20of%20antidiabetic%20compounds%20from%20neglected%20weed%20Mimosa%20pudica%20using%20supercritical%20CO2%20and%20CO2-Soxhlet.pdf Tasnuva Sarwar Tunna and Sarker, Md Zaidul Islam and Ghafoor, Kashif and Ferdosh, Sahena and Jaffri, Juliana Md and Al-Juhaimi, Fahad Y and Selamat, Jinap and Ali, Md Eaqub and Md Jahurul Haque Akanda and Awal, Md Shihabul and Ahmed, Qamar Uddin (2017) Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet. Journal Separation Science and Technology, 53 (2). pp. 243-260. ttps://doi.org/10.1080/01496395.2017.1384015
institution Universiti Malaysia Sabah
building UMS Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sabah
content_source UMS Institutional Repository
url_provider http://eprints.ums.edu.my/
language English
topic QK Botany
spellingShingle QK Botany
Tasnuva Sarwar Tunna
Sarker, Md Zaidul Islam
Ghafoor, Kashif
Ferdosh, Sahena
Jaffri, Juliana Md
Al-Juhaimi, Fahad Y
Selamat, Jinap
Ali, Md Eaqub
Md Jahurul Haque Akanda
Awal, Md Shihabul
Ahmed, Qamar Uddin
Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
description Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts were analyzed pharmacologically, qualitatively and quantitatively to ascertain enrichment levels. All three antidiabetic compounds were effectively enriched under optimized conditions of temperature 60°C, pressure 40 MPa, co-solvent ratio 30%, and CO2 flow rate of 5 ml min−1. SFE was found to be the better method for enrichment of the antidiabetic compounds than the CO2-Soxhlet method. Extraction conditions were seen to affect the enrichment of desired compounds.
format Article
author Tasnuva Sarwar Tunna
Sarker, Md Zaidul Islam
Ghafoor, Kashif
Ferdosh, Sahena
Jaffri, Juliana Md
Al-Juhaimi, Fahad Y
Selamat, Jinap
Ali, Md Eaqub
Md Jahurul Haque Akanda
Awal, Md Shihabul
Ahmed, Qamar Uddin
author_facet Tasnuva Sarwar Tunna
Sarker, Md Zaidul Islam
Ghafoor, Kashif
Ferdosh, Sahena
Jaffri, Juliana Md
Al-Juhaimi, Fahad Y
Selamat, Jinap
Ali, Md Eaqub
Md Jahurul Haque Akanda
Awal, Md Shihabul
Ahmed, Qamar Uddin
author_sort Tasnuva Sarwar Tunna
title Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_short Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_full Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_fullStr Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_full_unstemmed Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_sort enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed mimosa pudica using supercritical co2 and co2-soxhlet
publishDate 2017
url https://eprints.ums.edu.my/id/eprint/23697/1/Enrichmentin%20vitro%2C%20and%20quantification%20study%20of%20antidiabetic%20compounds%20from%20neglected%20weed%20Mimosa%20pudica%20using%20supercritical%20CO2%20and%20CO2-Soxhlet.pdf
https://eprints.ums.edu.my/id/eprint/23697/
_version_ 1760230142309826560
score 13.211869

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