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Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase

The purpose of the study was to develop a qualitative measurement for pain by measuring salivary alpha amylase (sAA). In this study, sAA levels were measured in order to investigate the relativity between fluctuation of sAA and pain on Institute of Cancer Research (ICR) mice by injection needle as a...

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Main Authors: Mohd Yusri, Saidin, Tsuchiya, Kazuyoshi, Inoue, Takehiko, Kajiwara, Kagemasa, Kimura, Minoru
Format: Article
Language:English
Published: Elsevier 2014
Subjects:
TJ Mechanical engineering and machinery
Online Access:http://umpir.ump.edu.my/id/eprint/5820/1/fkm-2014-yusri-qualitative_measurement_abs_only.pdf
http://umpir.ump.edu.my/id/eprint/5820/
http://dx.doi.org/10.1016/j.precisioneng.2013.09.006
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spelling my.ump.umpir.58202015-03-03T09:26:44Z http://umpir.ump.edu.my/id/eprint/5820/ Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase Mohd Yusri, Saidin Tsuchiya, Kazuyoshi Inoue, Takehiko Kajiwara, Kagemasa Kimura, Minoru TJ Mechanical engineering and machinery The purpose of the study was to develop a qualitative measurement for pain by measuring salivary alpha amylase (sAA). In this study, sAA levels were measured in order to investigate the relativity between fluctuation of sAA and pain on Institute of Cancer Research (ICR) mice by injection needle as a physical stimulus. Mice were chosen as an object of experiment since mice and human have similarities in both physical behaviour and biological behaviour. Here, ICR mice were divided into two groups; injected by Nanopass 33 (TERUMO Corporation, 100 μm and 200 μm in inner and outer diameter) and a control (without any injection). Whole saliva was collected from the oral cavity by micropipette for both groups. As a result, there was a significant difference in sAA levels between the two groups as the p value (probability value) was below than 0.01 (p < 0.01). Therefore, this is the first study showing the non-invasive method of qualitative pain measurement for minor damage caused by physical stimulus. The results demonstrate the potential of sAA as an indirect marker for pain and suggest that the present experimental situation is a suitable experimental model for measuring pain. Elsevier 2014-04 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/5820/1/fkm-2014-yusri-qualitative_measurement_abs_only.pdf Mohd Yusri, Saidin and Tsuchiya, Kazuyoshi and Inoue, Takehiko and Kajiwara, Kagemasa and Kimura, Minoru (2014) Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase. Precision Engineering, 38 (2). 257-260 . ISSN 0141-6359 http://dx.doi.org/10.1016/j.precisioneng.2013.09.006 DOI: 10.1016/j.precisioneng.2013.09.006
institution Universiti Malaysia Pahang
building UMP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang
content_source UMP Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
topic TJ Mechanical engineering and machinery
spellingShingle TJ Mechanical engineering and machinery
Mohd Yusri, Saidin
Tsuchiya, Kazuyoshi
Inoue, Takehiko
Kajiwara, Kagemasa
Kimura, Minoru
Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase
description The purpose of the study was to develop a qualitative measurement for pain by measuring salivary alpha amylase (sAA). In this study, sAA levels were measured in order to investigate the relativity between fluctuation of sAA and pain on Institute of Cancer Research (ICR) mice by injection needle as a physical stimulus. Mice were chosen as an object of experiment since mice and human have similarities in both physical behaviour and biological behaviour. Here, ICR mice were divided into two groups; injected by Nanopass 33 (TERUMO Corporation, 100 μm and 200 μm in inner and outer diameter) and a control (without any injection). Whole saliva was collected from the oral cavity by micropipette for both groups. As a result, there was a significant difference in sAA levels between the two groups as the p value (probability value) was below than 0.01 (p < 0.01). Therefore, this is the first study showing the non-invasive method of qualitative pain measurement for minor damage caused by physical stimulus. The results demonstrate the potential of sAA as an indirect marker for pain and suggest that the present experimental situation is a suitable experimental model for measuring pain.
format Article
author Mohd Yusri, Saidin
Tsuchiya, Kazuyoshi
Inoue, Takehiko
Kajiwara, Kagemasa
Kimura, Minoru
author_facet Mohd Yusri, Saidin
Tsuchiya, Kazuyoshi
Inoue, Takehiko
Kajiwara, Kagemasa
Kimura, Minoru
author_sort Mohd Yusri, Saidin
title Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase
title_short Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase
title_full Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase
title_fullStr Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase
title_full_unstemmed Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase
title_sort qualitative measurement of pain by analysing the salivary alpha amylase
publisher Elsevier
publishDate 2014
url http://umpir.ump.edu.my/id/eprint/5820/1/fkm-2014-yusri-qualitative_measurement_abs_only.pdf
http://umpir.ump.edu.my/id/eprint/5820/
http://dx.doi.org/10.1016/j.precisioneng.2013.09.006
_version_ 1643665255858962432
score 13.211869

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