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The Flavokawains: Uprising Medicinal Chalcones

lant-based compounds have been in the spotlight in search of new and promising drugs. Flavokawain A, B and C are naturally occurring chalcones that have been isolated from several medicinal plants; namely the piper methysticum or commercially known as the kava-kava. Multiple researches have been don...

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Main Authors: Akhtar, Muhammad Nadeem, Nadiah, Abu, Wan, Yong Ho, Swee, Keong Yeap, Mohd Puad, Abdullah, Abdul Rahman, Omar, Noorjahan Banu, Alitheen
Format: Article
Language:English
Published: BioMed Central 2013
Subjects:
QR Microbiology
Online Access:http://umpir.ump.edu.my/id/eprint/5209/1/fist-2013-nadeem-artFlavokawainsUprising.pdf
http://umpir.ump.edu.my/id/eprint/5209/
http://dx.doi.org/10.1186/1475-2867-13-102
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spelling my.ump.umpir.52092018-04-19T00:58:12Z http://umpir.ump.edu.my/id/eprint/5209/ The Flavokawains: Uprising Medicinal Chalcones Akhtar, Muhammad Nadeem Nadiah, Abu Wan, Yong Ho Swee, Keong Yeap Mohd Puad, Abdullah Abdul Rahman, Omar Noorjahan Banu, Alitheen QR Microbiology lant-based compounds have been in the spotlight in search of new and promising drugs. Flavokawain A, B and C are naturally occurring chalcones that have been isolated from several medicinal plants; namely the piper methysticum or commercially known as the kava-kava. Multiple researches have been done to evaluate the bioactivities of these compounds. It has been shown that all three flavokawains may hold promising anti-cancer effects. It has also been revealed that both flavokawain A and B are involved in the induction of cell cycle arrest in several cancer cell lines. Nevertheless, flavokawain B was shown to be more effective in treating in vitro cancer cell lines as compared to flavokawain A and C. Flavokawain B also exerts antinociceptive effects as well as anti-inflammation properties. This mini-review attempts to discuss the biological properties of all the flavokawains that have been reported. BioMed Central 2013 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/5209/1/fist-2013-nadeem-artFlavokawainsUprising.pdf Akhtar, Muhammad Nadeem and Nadiah, Abu and Wan, Yong Ho and Swee, Keong Yeap and Mohd Puad, Abdullah and Abdul Rahman, Omar and Noorjahan Banu, Alitheen (2013) The Flavokawains: Uprising Medicinal Chalcones. Cancer Cell International, 13 (201). pp. 1-7. ISSN 1475-2867 (print); 1475-2867 (online) http://dx.doi.org/10.1186/1475-2867-13-102 DOI: 10.1186/1475-2867-13-102
institution Universiti Malaysia Pahang
building UMP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang
content_source UMP Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
topic QR Microbiology
spellingShingle QR Microbiology
Akhtar, Muhammad Nadeem
Nadiah, Abu
Wan, Yong Ho
Swee, Keong Yeap
Mohd Puad, Abdullah
Abdul Rahman, Omar
Noorjahan Banu, Alitheen
The Flavokawains: Uprising Medicinal Chalcones
description lant-based compounds have been in the spotlight in search of new and promising drugs. Flavokawain A, B and C are naturally occurring chalcones that have been isolated from several medicinal plants; namely the piper methysticum or commercially known as the kava-kava. Multiple researches have been done to evaluate the bioactivities of these compounds. It has been shown that all three flavokawains may hold promising anti-cancer effects. It has also been revealed that both flavokawain A and B are involved in the induction of cell cycle arrest in several cancer cell lines. Nevertheless, flavokawain B was shown to be more effective in treating in vitro cancer cell lines as compared to flavokawain A and C. Flavokawain B also exerts antinociceptive effects as well as anti-inflammation properties. This mini-review attempts to discuss the biological properties of all the flavokawains that have been reported.
format Article
author Akhtar, Muhammad Nadeem
Nadiah, Abu
Wan, Yong Ho
Swee, Keong Yeap
Mohd Puad, Abdullah
Abdul Rahman, Omar
Noorjahan Banu, Alitheen
author_facet Akhtar, Muhammad Nadeem
Nadiah, Abu
Wan, Yong Ho
Swee, Keong Yeap
Mohd Puad, Abdullah
Abdul Rahman, Omar
Noorjahan Banu, Alitheen
author_sort Akhtar, Muhammad Nadeem
title The Flavokawains: Uprising Medicinal Chalcones
title_short The Flavokawains: Uprising Medicinal Chalcones
title_full The Flavokawains: Uprising Medicinal Chalcones
title_fullStr The Flavokawains: Uprising Medicinal Chalcones
title_full_unstemmed The Flavokawains: Uprising Medicinal Chalcones
title_sort flavokawains: uprising medicinal chalcones
publisher BioMed Central
publishDate 2013
url http://umpir.ump.edu.my/id/eprint/5209/1/fist-2013-nadeem-artFlavokawainsUprising.pdf
http://umpir.ump.edu.my/id/eprint/5209/
http://dx.doi.org/10.1186/1475-2867-13-102
_version_ 1643665159530479616
score 13.211869

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