Design, synthesis, structural characterization, cytotoxicity and computational studies of Usnic acid derivative as potential anti-breast cancer agent against MCF7 and T47D cell lines
Development of novel inhibitors is necessary to counteract the rising prevalence of breast cancer (BC) in women in recent years, as evidenced by the side-effect profiles of a few clinically approved inhibitors. In this study, the usnic acid derivative (UA1) was synthesized due to the effectiveness o...
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Main Authors: | Roney, Miah, Wong, Kelvin Khai Voon, Uddin, Md. Nazim, Rullah, Kamal, Septama, Abdi Wira, Antika, Lucia Dwi, Mohd Fadhlizil Fasihi, Mohd Aluwi |
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Format: | Article |
Language: | English |
Published: |
Elsevier Ltd
2025
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Subjects: | |
Online Access: | http://umpir.ump.edu.my/id/eprint/43154/1/Design%2C%20synthesis%2C%20structural%20characterization%2C%20cytotoxicity%20and%20computational%20studies%20of%20Usnic%20acid%20derivative%20as%20potential%20anti-breast%20cancer%20agent%20against%20MCF7%20and%20T47D%20cell%20lines.pdf http://umpir.ump.edu.my/id/eprint/43154/ https://doi.org/10.1016/j.compbiolchem.2024.108303 |
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