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Polycaprolactone/Cellulose acetate loaded psidium guajava essential oil electrospun nanofibrous mat dressing for healing wounds

Natural products and essential oils of medicinal plants are extensively employed in wound healing, particularly in the pharmaceutical industry. Essential oils obtained from Psidium guajava were utilised as an antibacterial agent against Bacillus subtilis, Staphylococcus aureus, and Enterococcus faec...

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Main Authors: Nor Naimah, Hussin @ Hassan, Noor Suhana, Adzahar, Lee, Thong Chuan, Izan Izwan, Misnon, Venugopal, Jayarama Reddy
Format: Article
Language:English
English
Published: Malaysian Society of Applied Biology 2023
Subjects:
HD Industries. Land use. Labor
Q Science (General)
T Technology (General)
Online Access:http://umpir.ump.edu.my/id/eprint/42863/1/Polycaprolactone_cellulose%20acetate%20loaded%20psidium%20guajava.pdf
http://umpir.ump.edu.my/id/eprint/42863/2/Polycaprolactone_cellulose%20acetate%20loaded%20psidium%20guajava%20essential%20oil%20electrospun%20nanofibrous%20mat%20dressing%20for%20healing%20wounds_ABS.pdf
http://umpir.ump.edu.my/id/eprint/42863/
https://doi.org/10.55230/mabjournal.v52i4.a094
https://doi.org/10.55230/mabjournal.v52i4.a094
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spelling my.ump.umpir.428632025-01-07T04:58:30Z http://umpir.ump.edu.my/id/eprint/42863/ Polycaprolactone/Cellulose acetate loaded psidium guajava essential oil electrospun nanofibrous mat dressing for healing wounds Nor Naimah, Hussin @ Hassan Noor Suhana, Adzahar Lee, Thong Chuan Izan Izwan, Misnon Venugopal, Jayarama Reddy HD Industries. Land use. Labor Q Science (General) T Technology (General) Natural products and essential oils of medicinal plants are extensively employed in wound healing, particularly in the pharmaceutical industry. Essential oils obtained from Psidium guajava were utilised as an antibacterial agent against Bacillus subtilis, Staphylococcus aureus, and Enterococcus faecalis, and to control drug-resistant strains. In this study, electrospinning for applications in antimicrobial activity and drug delivery systems was used to develop biocomposite nanofibers of Polycaprolactone (PCL)/Cellulose Acetate (CA) and Psidium guajava essential oil (PGEO). Images from the FESEM revealed that the mean fire diameters were 120 nm for the PCL/CA and 223 nm for PCL/CA/PGEO biocomposite nanofibers. The diameters of the nanofibers were increased following the addition of PGEO into PCL/CA nanofibers. Furthermore, FTIR studies revealed the-OH peak in pure electrospun PCL/CA and PCL/CA/PGEO, lacking pure PGEO nanofibrous mats. These findings reflect that Psidium guajava essential oil/PCL/CA electrospun nanofibers are promising candidates for presenting bioactive compounds in wound management or other approaches for wound healing and bacterial infections. Malaysian Society of Applied Biology 2023-10-31 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/42863/1/Polycaprolactone_cellulose%20acetate%20loaded%20psidium%20guajava.pdf pdf en http://umpir.ump.edu.my/id/eprint/42863/2/Polycaprolactone_cellulose%20acetate%20loaded%20psidium%20guajava%20essential%20oil%20electrospun%20nanofibrous%20mat%20dressing%20for%20healing%20wounds_ABS.pdf Nor Naimah, Hussin @ Hassan and Noor Suhana, Adzahar and Lee, Thong Chuan and Izan Izwan, Misnon and Venugopal, Jayarama Reddy (2023) Polycaprolactone/Cellulose acetate loaded psidium guajava essential oil electrospun nanofibrous mat dressing for healing wounds. Malaysian Applied Biology, 52 (4). pp. 107-112. ISSN 0126-8643. (Published) https://doi.org/10.55230/mabjournal.v52i4.a094 https://doi.org/10.55230/mabjournal.v52i4.a094
institution Universiti Malaysia Pahang Al-Sultan Abdullah
building UMPSA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang Al-Sultan Abdullah
content_source UMPSA Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
English
topic HD Industries. Land use. Labor
Q Science (General)
T Technology (General)
spellingShingle HD Industries. Land use. Labor
Q Science (General)
T Technology (General)
Nor Naimah, Hussin @ Hassan
Noor Suhana, Adzahar
Lee, Thong Chuan
Izan Izwan, Misnon
Venugopal, Jayarama Reddy
Polycaprolactone/Cellulose acetate loaded psidium guajava essential oil electrospun nanofibrous mat dressing for healing wounds
description Natural products and essential oils of medicinal plants are extensively employed in wound healing, particularly in the pharmaceutical industry. Essential oils obtained from Psidium guajava were utilised as an antibacterial agent against Bacillus subtilis, Staphylococcus aureus, and Enterococcus faecalis, and to control drug-resistant strains. In this study, electrospinning for applications in antimicrobial activity and drug delivery systems was used to develop biocomposite nanofibers of Polycaprolactone (PCL)/Cellulose Acetate (CA) and Psidium guajava essential oil (PGEO). Images from the FESEM revealed that the mean fire diameters were 120 nm for the PCL/CA and 223 nm for PCL/CA/PGEO biocomposite nanofibers. The diameters of the nanofibers were increased following the addition of PGEO into PCL/CA nanofibers. Furthermore, FTIR studies revealed the-OH peak in pure electrospun PCL/CA and PCL/CA/PGEO, lacking pure PGEO nanofibrous mats. These findings reflect that Psidium guajava essential oil/PCL/CA electrospun nanofibers are promising candidates for presenting bioactive compounds in wound management or other approaches for wound healing and bacterial infections.
format Article
author Nor Naimah, Hussin @ Hassan
Noor Suhana, Adzahar
Lee, Thong Chuan
Izan Izwan, Misnon
Venugopal, Jayarama Reddy
author_facet Nor Naimah, Hussin @ Hassan
Noor Suhana, Adzahar
Lee, Thong Chuan
Izan Izwan, Misnon
Venugopal, Jayarama Reddy
author_sort Nor Naimah, Hussin @ Hassan
title Polycaprolactone/Cellulose acetate loaded psidium guajava essential oil electrospun nanofibrous mat dressing for healing wounds
title_short Polycaprolactone/Cellulose acetate loaded psidium guajava essential oil electrospun nanofibrous mat dressing for healing wounds
title_full Polycaprolactone/Cellulose acetate loaded psidium guajava essential oil electrospun nanofibrous mat dressing for healing wounds
title_fullStr Polycaprolactone/Cellulose acetate loaded psidium guajava essential oil electrospun nanofibrous mat dressing for healing wounds
title_full_unstemmed Polycaprolactone/Cellulose acetate loaded psidium guajava essential oil electrospun nanofibrous mat dressing for healing wounds
title_sort polycaprolactone/cellulose acetate loaded psidium guajava essential oil electrospun nanofibrous mat dressing for healing wounds
publisher Malaysian Society of Applied Biology
publishDate 2023
url http://umpir.ump.edu.my/id/eprint/42863/1/Polycaprolactone_cellulose%20acetate%20loaded%20psidium%20guajava.pdf
http://umpir.ump.edu.my/id/eprint/42863/2/Polycaprolactone_cellulose%20acetate%20loaded%20psidium%20guajava%20essential%20oil%20electrospun%20nanofibrous%20mat%20dressing%20for%20healing%20wounds_ABS.pdf
http://umpir.ump.edu.my/id/eprint/42863/
https://doi.org/10.55230/mabjournal.v52i4.a094
https://doi.org/10.55230/mabjournal.v52i4.a094
_version_ 1822924891896152064
score 13.23648

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