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Fluid-structure interaction modelling of blood flow in peripheral arterial disease

The study presents the fluid-structure interaction (FSI) modeling in Peripheral Arterial Disease (PAD) geometry, highlighting the effects of arterial blockage on hemodynamics and arterial wall mechanics. Employing a RANS-based SST-Tran model, the study examines stenotic PAD models under realistic bo...

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Main Authors: Muhammad Firdaus, Mohd Fauzi, Nasrul Hadi, Johari, Mohd Jamil, Mohamed Mokhtarudin, Bazli, Mohd Yusoff, Guo, Baolei
Format: Article
Language:English
Published: Semarak Ilmu Publishing 2024
Subjects:
RS Pharmacy and materia medica
TJ Mechanical engineering and machinery
Online Access:http://umpir.ump.edu.my/id/eprint/42589/1/Fluid-structure%20interaction%20modelling%20of%20blood%20flow%20in%20peripheral%20arterial%20disease.pdf
http://umpir.ump.edu.my/id/eprint/42589/
https://doi.org/10.37934/arfmts.119.1.117133
https://doi.org/10.37934/arfmts.119.1.117133
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spelling my.ump.umpir.425892024-09-17T01:05:05Z http://umpir.ump.edu.my/id/eprint/42589/ Fluid-structure interaction modelling of blood flow in peripheral arterial disease Muhammad Firdaus, Mohd Fauzi Nasrul Hadi, Johari Mohd Jamil, Mohamed Mokhtarudin Bazli, Mohd Yusoff Guo, Baolei RS Pharmacy and materia medica TJ Mechanical engineering and machinery The study presents the fluid-structure interaction (FSI) modeling in Peripheral Arterial Disease (PAD) geometry, highlighting the effects of arterial blockage on hemodynamics and arterial wall mechanics. Employing a RANS-based SST-Tran model, the study examines stenotic PAD models under realistic boundary conditions, coupled with a hyperelastic Mooney-Rivlin model to simulate the arterial wall's response. The analysis includes velocity profiles, wall shear stress (WSS), pressure distribution, and wall displacement, revealing significant differences between healthy and stenosed models. It demonstrates adaptive hemodynamics, the impact of stenosis on flow mechanics, and potential implications for atherosclerosis and plaque formation. The findings highlight the importance of understanding stenosis severity for clinical risk assessment, treatment planning, and monitoring. Semarak Ilmu Publishing 2024-07 Article PeerReviewed pdf en cc_by_4 http://umpir.ump.edu.my/id/eprint/42589/1/Fluid-structure%20interaction%20modelling%20of%20blood%20flow%20in%20peripheral%20arterial%20disease.pdf Muhammad Firdaus, Mohd Fauzi and Nasrul Hadi, Johari and Mohd Jamil, Mohamed Mokhtarudin and Bazli, Mohd Yusoff and Guo, Baolei (2024) Fluid-structure interaction modelling of blood flow in peripheral arterial disease. Journal of Advanced Research in Fluid Mechanics and Thermal Sciences, 119 (1). 117 -133. ISSN 2289-7879. (Published) https://doi.org/10.37934/arfmts.119.1.117133 https://doi.org/10.37934/arfmts.119.1.117133
institution Universiti Malaysia Pahang Al-Sultan Abdullah
building UMPSA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang Al-Sultan Abdullah
content_source UMPSA Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
topic RS Pharmacy and materia medica
TJ Mechanical engineering and machinery
spellingShingle RS Pharmacy and materia medica
TJ Mechanical engineering and machinery
Muhammad Firdaus, Mohd Fauzi
Nasrul Hadi, Johari
Mohd Jamil, Mohamed Mokhtarudin
Bazli, Mohd Yusoff
Guo, Baolei
Fluid-structure interaction modelling of blood flow in peripheral arterial disease
description The study presents the fluid-structure interaction (FSI) modeling in Peripheral Arterial Disease (PAD) geometry, highlighting the effects of arterial blockage on hemodynamics and arterial wall mechanics. Employing a RANS-based SST-Tran model, the study examines stenotic PAD models under realistic boundary conditions, coupled with a hyperelastic Mooney-Rivlin model to simulate the arterial wall's response. The analysis includes velocity profiles, wall shear stress (WSS), pressure distribution, and wall displacement, revealing significant differences between healthy and stenosed models. It demonstrates adaptive hemodynamics, the impact of stenosis on flow mechanics, and potential implications for atherosclerosis and plaque formation. The findings highlight the importance of understanding stenosis severity for clinical risk assessment, treatment planning, and monitoring.
format Article
author Muhammad Firdaus, Mohd Fauzi
Nasrul Hadi, Johari
Mohd Jamil, Mohamed Mokhtarudin
Bazli, Mohd Yusoff
Guo, Baolei
author_facet Muhammad Firdaus, Mohd Fauzi
Nasrul Hadi, Johari
Mohd Jamil, Mohamed Mokhtarudin
Bazli, Mohd Yusoff
Guo, Baolei
author_sort Muhammad Firdaus, Mohd Fauzi
title Fluid-structure interaction modelling of blood flow in peripheral arterial disease
title_short Fluid-structure interaction modelling of blood flow in peripheral arterial disease
title_full Fluid-structure interaction modelling of blood flow in peripheral arterial disease
title_fullStr Fluid-structure interaction modelling of blood flow in peripheral arterial disease
title_full_unstemmed Fluid-structure interaction modelling of blood flow in peripheral arterial disease
title_sort fluid-structure interaction modelling of blood flow in peripheral arterial disease
publisher Semarak Ilmu Publishing
publishDate 2024
url http://umpir.ump.edu.my/id/eprint/42589/1/Fluid-structure%20interaction%20modelling%20of%20blood%20flow%20in%20peripheral%20arterial%20disease.pdf
http://umpir.ump.edu.my/id/eprint/42589/
https://doi.org/10.37934/arfmts.119.1.117133
https://doi.org/10.37934/arfmts.119.1.117133
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score 13.244413

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