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Effect of extraction methods on yield, total phenolic content, antioxidant, and anti-tyrosinase properties of combretum indicum leaves

Plants form a natural source of key bioactive chemicals equipped with excellent antioxidant and anti-tyrosinase properties. The restorative plant Combretum indicum (C. indicum), which belongs to the Combretaceae family, was widely used in customary treatment in the past. The target of this study is...

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Main Authors: Thanaseelan, Tanesha, Nur Aina Raihana, Muhamad Yusuff, Kutty, Rajaletchumy Veloo
Format: Article
Language:English
Published: The Malaysian Analytical Sciences Society 2024
Subjects:
TP Chemical technology
Online Access:http://umpir.ump.edu.my/id/eprint/42509/1/Effect%20of%20extraction%20methods%20on%20yield%2C%20total%20phenolic%20content%2C%20antioxidant%2C%20and%20anti-tyrosinase%20properties%20of%20combretum%20indicum%20leaves.pdf
http://umpir.ump.edu.my/id/eprint/42509/
https://mjas.analis.com.my/mjas/v28_n4/pdf/Thanaseelan_28_4_4.pdf
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spelling my.ump.umpir.425092024-09-05T06:49:17Z http://umpir.ump.edu.my/id/eprint/42509/ Effect of extraction methods on yield, total phenolic content, antioxidant, and anti-tyrosinase properties of combretum indicum leaves Thanaseelan, Tanesha Nur Aina Raihana, Muhamad Yusuff Kutty, Rajaletchumy Veloo TP Chemical technology Plants form a natural source of key bioactive chemicals equipped with excellent antioxidant and anti-tyrosinase properties. The restorative plant Combretum indicum (C. indicum), which belongs to the Combretaceae family, was widely used in customary treatment in the past. The target of this study is to assess the effects of water as a solvent, traditional extraction strategies (maceration and Soxhlet extraction), and extraction time on C. indicum yield. The total phenolic content (TPC), as well as antioxidant and tyrosinase inhibitory activities, were observed by utilising an ultraviolet-visible spectrophotometer. DPPH radical scavenging was used to determine the antioxidant property, while a mushroom tyrosinase inhibition assay was utilised to evaluate the anti-tyrosinase activity. Maceration carried out for 72 h showed good outcomes for TPC, antioxidant, and anti-tyrosinase activities. The results showed that TPC, antioxidant assay, and anti-tyrosinase activities had a significant linear correlation (p <0.05). It is evident from the study that C. indicum leaves, which contain numerous phytochemicals, are strong antioxidants and tyrosinase inhibitors that can potentially play a significant role in the pharmaceutical and cosmetic industries. The Malaysian Analytical Sciences Society 2024 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/42509/1/Effect%20of%20extraction%20methods%20on%20yield%2C%20total%20phenolic%20content%2C%20antioxidant%2C%20and%20anti-tyrosinase%20properties%20of%20combretum%20indicum%20leaves.pdf Thanaseelan, Tanesha and Nur Aina Raihana, Muhamad Yusuff and Kutty, Rajaletchumy Veloo (2024) Effect of extraction methods on yield, total phenolic content, antioxidant, and anti-tyrosinase properties of combretum indicum leaves. Malaysian Journal of Analytical Sciences, 28 (4). pp. 758-767. ISSN 1394 - 2506. (Published) https://mjas.analis.com.my/mjas/v28_n4/pdf/Thanaseelan_28_4_4.pdf
institution Universiti Malaysia Pahang Al-Sultan Abdullah
building UMPSA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang Al-Sultan Abdullah
content_source UMPSA Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
topic TP Chemical technology
spellingShingle TP Chemical technology
Thanaseelan, Tanesha
Nur Aina Raihana, Muhamad Yusuff
Kutty, Rajaletchumy Veloo
Effect of extraction methods on yield, total phenolic content, antioxidant, and anti-tyrosinase properties of combretum indicum leaves
description Plants form a natural source of key bioactive chemicals equipped with excellent antioxidant and anti-tyrosinase properties. The restorative plant Combretum indicum (C. indicum), which belongs to the Combretaceae family, was widely used in customary treatment in the past. The target of this study is to assess the effects of water as a solvent, traditional extraction strategies (maceration and Soxhlet extraction), and extraction time on C. indicum yield. The total phenolic content (TPC), as well as antioxidant and tyrosinase inhibitory activities, were observed by utilising an ultraviolet-visible spectrophotometer. DPPH radical scavenging was used to determine the antioxidant property, while a mushroom tyrosinase inhibition assay was utilised to evaluate the anti-tyrosinase activity. Maceration carried out for 72 h showed good outcomes for TPC, antioxidant, and anti-tyrosinase activities. The results showed that TPC, antioxidant assay, and anti-tyrosinase activities had a significant linear correlation (p <0.05). It is evident from the study that C. indicum leaves, which contain numerous phytochemicals, are strong antioxidants and tyrosinase inhibitors that can potentially play a significant role in the pharmaceutical and cosmetic industries.
format Article
author Thanaseelan, Tanesha
Nur Aina Raihana, Muhamad Yusuff
Kutty, Rajaletchumy Veloo
author_facet Thanaseelan, Tanesha
Nur Aina Raihana, Muhamad Yusuff
Kutty, Rajaletchumy Veloo
author_sort Thanaseelan, Tanesha
title Effect of extraction methods on yield, total phenolic content, antioxidant, and anti-tyrosinase properties of combretum indicum leaves
title_short Effect of extraction methods on yield, total phenolic content, antioxidant, and anti-tyrosinase properties of combretum indicum leaves
title_full Effect of extraction methods on yield, total phenolic content, antioxidant, and anti-tyrosinase properties of combretum indicum leaves
title_fullStr Effect of extraction methods on yield, total phenolic content, antioxidant, and anti-tyrosinase properties of combretum indicum leaves
title_full_unstemmed Effect of extraction methods on yield, total phenolic content, antioxidant, and anti-tyrosinase properties of combretum indicum leaves
title_sort effect of extraction methods on yield, total phenolic content, antioxidant, and anti-tyrosinase properties of combretum indicum leaves
publisher The Malaysian Analytical Sciences Society
publishDate 2024
url http://umpir.ump.edu.my/id/eprint/42509/1/Effect%20of%20extraction%20methods%20on%20yield%2C%20total%20phenolic%20content%2C%20antioxidant%2C%20and%20anti-tyrosinase%20properties%20of%20combretum%20indicum%20leaves.pdf
http://umpir.ump.edu.my/id/eprint/42509/
https://mjas.analis.com.my/mjas/v28_n4/pdf/Thanaseelan_28_4_4.pdf
_version_ 1822924653327286272
score 13.235796

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