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Advancement of lignin into bioactive compounds through selective organic synthesis methods

The conversion of lignin into bioactive compounds through selective organic synthesis methods represents a promising frontier in the pursuit of sustainable raw materials and green chemistry. This review explores the versatility of lignin-derived bioactive compounds, ranging from their application in...

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Main Authors: Jadhav, Pramod, Bhuyar, Prakash, Izan Izwan, Misnon, Mohd Hasbi, Ab Rahim, Rasidi, Roslan
Format: Article
Language:English
English
Published: Elsevier Ltd 2024
Subjects:
Q Science (General)
TP Chemical technology
Online Access:http://umpir.ump.edu.my/id/eprint/42386/1/Advancement%20of%20lignin%20into%20bioactive%20compounds_ABST.pdf
http://umpir.ump.edu.my/id/eprint/42386/2/Advancement%20of%20lignin%20into%20bioactive%20compounds.pdf
http://umpir.ump.edu.my/id/eprint/42386/
https://doi.org/10.1016/j.ijbiomac.2024.134061
https://doi.org/10.1016/j.ijbiomac.2024.134061
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spelling my.ump.umpir.423862024-08-16T08:22:47Z http://umpir.ump.edu.my/id/eprint/42386/ Advancement of lignin into bioactive compounds through selective organic synthesis methods Jadhav, Pramod Bhuyar, Prakash Izan Izwan, Misnon Mohd Hasbi, Ab Rahim Rasidi, Roslan Q Science (General) TP Chemical technology The conversion of lignin into bioactive compounds through selective organic synthesis methods represents a promising frontier in the pursuit of sustainable raw materials and green chemistry. This review explores the versatility of lignin-derived bioactive compounds, ranging from their application in drug discovery to their role in the development of biodegradable materials. Despite notable advancements, the synthesis routes and yields of highly bioactive molecules from lignin still require further exploration and improvement. This review provides an in-depth examination of the progress made in understanding the complex structure of lignin and developing innovative approaches to exploit its potential. Specifically, the types of lignins covered include softwood Kraft lignin, hardwood organosolv lignin, and soda lignin. This work is divided into three parts: first, the transformation of lignin into bioactive molecules with chemically active centres and functionalised hydroxyl groups through depolymerisation; second, kinetic modelling techniques essential for understanding the chemical kinetics of lignin and enabling significant scaling up in the conversion of organic molecules; third, efficient catalytic pathways for synthesising molecules with anticancer and antibacterial properties. In conclusion, this comprehensive review spurs further investigations into lignin-derived bioactive compounds, their applications, and the advancement of sustainable processes. Elsevier Ltd 2024-07 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/42386/1/Advancement%20of%20lignin%20into%20bioactive%20compounds_ABST.pdf pdf en http://umpir.ump.edu.my/id/eprint/42386/2/Advancement%20of%20lignin%20into%20bioactive%20compounds.pdf Jadhav, Pramod and Bhuyar, Prakash and Izan Izwan, Misnon and Mohd Hasbi, Ab Rahim and Rasidi, Roslan (2024) Advancement of lignin into bioactive compounds through selective organic synthesis methods. International Journal of Biological Macromolecules, 276 (134061). pp. 1-10. ISSN 0141-8130. (Published) https://doi.org/10.1016/j.ijbiomac.2024.134061 https://doi.org/10.1016/j.ijbiomac.2024.134061
institution Universiti Malaysia Pahang Al-Sultan Abdullah
building UMPSA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang Al-Sultan Abdullah
content_source UMPSA Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
English
topic Q Science (General)
TP Chemical technology
spellingShingle Q Science (General)
TP Chemical technology
Jadhav, Pramod
Bhuyar, Prakash
Izan Izwan, Misnon
Mohd Hasbi, Ab Rahim
Rasidi, Roslan
Advancement of lignin into bioactive compounds through selective organic synthesis methods
description The conversion of lignin into bioactive compounds through selective organic synthesis methods represents a promising frontier in the pursuit of sustainable raw materials and green chemistry. This review explores the versatility of lignin-derived bioactive compounds, ranging from their application in drug discovery to their role in the development of biodegradable materials. Despite notable advancements, the synthesis routes and yields of highly bioactive molecules from lignin still require further exploration and improvement. This review provides an in-depth examination of the progress made in understanding the complex structure of lignin and developing innovative approaches to exploit its potential. Specifically, the types of lignins covered include softwood Kraft lignin, hardwood organosolv lignin, and soda lignin. This work is divided into three parts: first, the transformation of lignin into bioactive molecules with chemically active centres and functionalised hydroxyl groups through depolymerisation; second, kinetic modelling techniques essential for understanding the chemical kinetics of lignin and enabling significant scaling up in the conversion of organic molecules; third, efficient catalytic pathways for synthesising molecules with anticancer and antibacterial properties. In conclusion, this comprehensive review spurs further investigations into lignin-derived bioactive compounds, their applications, and the advancement of sustainable processes.
format Article
author Jadhav, Pramod
Bhuyar, Prakash
Izan Izwan, Misnon
Mohd Hasbi, Ab Rahim
Rasidi, Roslan
author_facet Jadhav, Pramod
Bhuyar, Prakash
Izan Izwan, Misnon
Mohd Hasbi, Ab Rahim
Rasidi, Roslan
author_sort Jadhav, Pramod
title Advancement of lignin into bioactive compounds through selective organic synthesis methods
title_short Advancement of lignin into bioactive compounds through selective organic synthesis methods
title_full Advancement of lignin into bioactive compounds through selective organic synthesis methods
title_fullStr Advancement of lignin into bioactive compounds through selective organic synthesis methods
title_full_unstemmed Advancement of lignin into bioactive compounds through selective organic synthesis methods
title_sort advancement of lignin into bioactive compounds through selective organic synthesis methods
publisher Elsevier Ltd
publishDate 2024
url http://umpir.ump.edu.my/id/eprint/42386/1/Advancement%20of%20lignin%20into%20bioactive%20compounds_ABST.pdf
http://umpir.ump.edu.my/id/eprint/42386/2/Advancement%20of%20lignin%20into%20bioactive%20compounds.pdf
http://umpir.ump.edu.my/id/eprint/42386/
https://doi.org/10.1016/j.ijbiomac.2024.134061
https://doi.org/10.1016/j.ijbiomac.2024.134061
_version_ 1822924616698429440
score 13.235362

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