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Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction

Commiphora gileadensis (C. gileadensis) is a medicinal plant with a variety of biological activity; its bark has several therapeutic potentials, including the treatment of wounds, inflammatory diseases, and treating bacterial infections. This study utilized microwave-assisted extraction (MAE) to opt...

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Main Authors: Aiman A., Mokaizh, Nour, Abdurahman Hamid, Ali, Gomaa A.M., Ukaegbu, Chinonso Ishmael, Hawege, Emsalem Faraj
Format: Article
Language:English
English
Published: Elsevier 2024
Subjects:
TP Chemical technology
Online Access:http://umpir.ump.edu.my/id/eprint/42360/1/Eco-friendly%20and%20efficient%20extraction%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark.pdf
http://umpir.ump.edu.my/id/eprint/42360/2/Eco-friendly%20and%20efficient%20extraction%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark%20using%20microwave-assisted%20extraction.pdf
http://umpir.ump.edu.my/id/eprint/42360/
https://doi.org/10.1016/j.jiec.2024.07.038
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spelling my.ump.umpir.423602024-08-14T08:38:30Z http://umpir.ump.edu.my/id/eprint/42360/ Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction Aiman A., Mokaizh Nour, Abdurahman Hamid Ali, Gomaa A.M. Ukaegbu, Chinonso Ishmael Hawege, Emsalem Faraj TP Chemical technology Commiphora gileadensis (C. gileadensis) is a medicinal plant with a variety of biological activity; its bark has several therapeutic potentials, including the treatment of wounds, inflammatory diseases, and treating bacterial infections. This study utilized microwave-assisted extraction (MAE) to optimize the recovery and phenolic components of the ethanolic extracts of C. gileadensis bark. Different MAE process parameters (microwave power, irradiation time, sample/solvent ratio, extraction temperature, and solvent (ethanol) concentration) were studied for their impacts on the extraction process using One-Factor-At-a-Time (OFAT) method. The extracts were further characterized for the presence of different phytochemicals using Gas Chromatography-Mass Spectroscopy (FC-MS) and Fourier Transform Infrared Spectroscopy (FTIR) analyses. The experimental findings revealed that the maximum extraction yield, total phenolic content (TPC), and total flavonoid content (TFC) of the ethanolic extract of the of C. gileadensis bark using MAE process were 39.40 ± 0.47 w/w%, 166.41 ± 3.97 mg GAE/g d.w., and 52.83 ± 2.95 mg QE/g d.w., respectively. Furthermore, 30 phenolic constituents were discovered in the extract of C. gileadensis bark for the first time, and these compounds showed good in vitro antioxidant activity. Hence, MAE is a suitable technique for efficient and green extraction of different groups of phytochemicals of pharmaceutical importance from the bark of C. gileadensis. Elsevier 2024 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/42360/1/Eco-friendly%20and%20efficient%20extraction%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark.pdf pdf en http://umpir.ump.edu.my/id/eprint/42360/2/Eco-friendly%20and%20efficient%20extraction%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark%20using%20microwave-assisted%20extraction.pdf Aiman A., Mokaizh and Nour, Abdurahman Hamid and Ali, Gomaa A.M. and Ukaegbu, Chinonso Ishmael and Hawege, Emsalem Faraj (2024) Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction. Journal of Industrial and Engineering Chemistry. pp. 1-8. ISSN 1226-086X. (In Press / Online First) (In Press / Online First) https://doi.org/10.1016/j.jiec.2024.07.038 10.1016/j.jiec.2024.07.038
institution Universiti Malaysia Pahang Al-Sultan Abdullah
building UMPSA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang Al-Sultan Abdullah
content_source UMPSA Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
English
topic TP Chemical technology
spellingShingle TP Chemical technology
Aiman A., Mokaizh
Nour, Abdurahman Hamid
Ali, Gomaa A.M.
Ukaegbu, Chinonso Ishmael
Hawege, Emsalem Faraj
Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction
description Commiphora gileadensis (C. gileadensis) is a medicinal plant with a variety of biological activity; its bark has several therapeutic potentials, including the treatment of wounds, inflammatory diseases, and treating bacterial infections. This study utilized microwave-assisted extraction (MAE) to optimize the recovery and phenolic components of the ethanolic extracts of C. gileadensis bark. Different MAE process parameters (microwave power, irradiation time, sample/solvent ratio, extraction temperature, and solvent (ethanol) concentration) were studied for their impacts on the extraction process using One-Factor-At-a-Time (OFAT) method. The extracts were further characterized for the presence of different phytochemicals using Gas Chromatography-Mass Spectroscopy (FC-MS) and Fourier Transform Infrared Spectroscopy (FTIR) analyses. The experimental findings revealed that the maximum extraction yield, total phenolic content (TPC), and total flavonoid content (TFC) of the ethanolic extract of the of C. gileadensis bark using MAE process were 39.40 ± 0.47 w/w%, 166.41 ± 3.97 mg GAE/g d.w., and 52.83 ± 2.95 mg QE/g d.w., respectively. Furthermore, 30 phenolic constituents were discovered in the extract of C. gileadensis bark for the first time, and these compounds showed good in vitro antioxidant activity. Hence, MAE is a suitable technique for efficient and green extraction of different groups of phytochemicals of pharmaceutical importance from the bark of C. gileadensis.
format Article
author Aiman A., Mokaizh
Nour, Abdurahman Hamid
Ali, Gomaa A.M.
Ukaegbu, Chinonso Ishmael
Hawege, Emsalem Faraj
author_facet Aiman A., Mokaizh
Nour, Abdurahman Hamid
Ali, Gomaa A.M.
Ukaegbu, Chinonso Ishmael
Hawege, Emsalem Faraj
author_sort Aiman A., Mokaizh
title Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction
title_short Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction
title_full Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction
title_fullStr Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction
title_full_unstemmed Eco-friendly and efficient extraction of phenolic compounds from Commiphora gileadensis bark using microwave-assisted extraction
title_sort eco-friendly and efficient extraction of phenolic compounds from commiphora gileadensis bark using microwave-assisted extraction
publisher Elsevier
publishDate 2024
url http://umpir.ump.edu.my/id/eprint/42360/1/Eco-friendly%20and%20efficient%20extraction%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark.pdf
http://umpir.ump.edu.my/id/eprint/42360/2/Eco-friendly%20and%20efficient%20extraction%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark%20using%20microwave-assisted%20extraction.pdf
http://umpir.ump.edu.my/id/eprint/42360/
https://doi.org/10.1016/j.jiec.2024.07.038
_version_ 1822924614778486784
score 13.235362

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