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Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction

Developing nations across the globe place significant importance on ensuring the complete protection, efficacy, and quality of herbal products and medicinal plants. Among these beneficial plants, Commiphora gileadensis stands out due to its diverse array of biological activities. The bark of this pl...

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Main Authors: Aiman A., Mokaizh, Nour, Abdurahman Hamid, Rosli, Mohd Yunus
Format: Article
Language:English
English
Published: Elsevier Ltd 2024
Subjects:
QD Chemistry
TP Chemical technology
Online Access:http://umpir.ump.edu.my/id/eprint/42358/1/Extraction%20and%20characterization%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark_ABST.pdf
http://umpir.ump.edu.my/id/eprint/42358/2/Extraction%20and%20characterization%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark.pdf
http://umpir.ump.edu.my/id/eprint/42358/
https://doi.org/10.1016/j.prenap.2024.100066
https://doi.org/10.1016/j.prenap.2024.100066
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spelling my.ump.umpir.423582024-08-14T07:15:21Z http://umpir.ump.edu.my/id/eprint/42358/ Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction Aiman A., Mokaizh Nour, Abdurahman Hamid Rosli, Mohd Yunus QD Chemistry TP Chemical technology Developing nations across the globe place significant importance on ensuring the complete protection, efficacy, and quality of herbal products and medicinal plants. Among these beneficial plants, Commiphora gileadensis stands out due to its diverse array of biological activities. The bark of this plant species offers numerous therapeutic advantages, including its potential for treating wounds, inflammatory conditions, and bacterial infections. To explore the process of extraction of biologically active components, this study employed ultrasonic-assisted extraction (UAE) on ethanolic extracts of C. gileadensis bark. Various variables of UAE process, such as ultrasonic frequency, extraction time, sample-to-solvent ratio, and ethanol concentration, were carefully investigated via the ‘’One-Factor-At-a-Time (OFAT)’’ method to understand their individual impacts on the extraction process. The obtained extracts underwent further analysis to identify the presence of different phytochemicals, employing techniques such as ‘’Gas Chromatography-Mass Spectroscopy (GC-MS) and Fourier Transform Infrared Spectroscopy (FTIR)’’. The experimental results demonstrated that the UAE process yielded promising outcomes, with the maximum extraction yields, total phenolic content (TPC), and total flavonoids content (TFC) of the ethanolic extract from C. gileadensis bark reaching 37.60 ± 0.31 %, 149.75 ± 3.23 mg GAE/g d.w., and 44.84 ± 3.02 mg QE/g d.w., respectively. Additionally, this study successfully identified a total of 30 phenolic compounds present in the C. gileadensis bark extract for the first time, highlighting the efficacy of UAE as a suitable method for efficiently extracting various groups of phytochemicals from the bark of C. gileadensis. Elsevier Ltd 2024-07-17 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/42358/1/Extraction%20and%20characterization%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark_ABST.pdf pdf en http://umpir.ump.edu.my/id/eprint/42358/2/Extraction%20and%20characterization%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark.pdf Aiman A., Mokaizh and Nour, Abdurahman Hamid and Rosli, Mohd Yunus (2024) Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction. Pharmacological Research - Natural Products, 4 (100066). pp. 1-8. ISSN 2950-1997. (Published) https://doi.org/10.1016/j.prenap.2024.100066 https://doi.org/10.1016/j.prenap.2024.100066
institution Universiti Malaysia Pahang Al-Sultan Abdullah
building UMPSA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang Al-Sultan Abdullah
content_source UMPSA Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
English
topic QD Chemistry
TP Chemical technology
spellingShingle QD Chemistry
TP Chemical technology
Aiman A., Mokaizh
Nour, Abdurahman Hamid
Rosli, Mohd Yunus
Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction
description Developing nations across the globe place significant importance on ensuring the complete protection, efficacy, and quality of herbal products and medicinal plants. Among these beneficial plants, Commiphora gileadensis stands out due to its diverse array of biological activities. The bark of this plant species offers numerous therapeutic advantages, including its potential for treating wounds, inflammatory conditions, and bacterial infections. To explore the process of extraction of biologically active components, this study employed ultrasonic-assisted extraction (UAE) on ethanolic extracts of C. gileadensis bark. Various variables of UAE process, such as ultrasonic frequency, extraction time, sample-to-solvent ratio, and ethanol concentration, were carefully investigated via the ‘’One-Factor-At-a-Time (OFAT)’’ method to understand their individual impacts on the extraction process. The obtained extracts underwent further analysis to identify the presence of different phytochemicals, employing techniques such as ‘’Gas Chromatography-Mass Spectroscopy (GC-MS) and Fourier Transform Infrared Spectroscopy (FTIR)’’. The experimental results demonstrated that the UAE process yielded promising outcomes, with the maximum extraction yields, total phenolic content (TPC), and total flavonoids content (TFC) of the ethanolic extract from C. gileadensis bark reaching 37.60 ± 0.31 %, 149.75 ± 3.23 mg GAE/g d.w., and 44.84 ± 3.02 mg QE/g d.w., respectively. Additionally, this study successfully identified a total of 30 phenolic compounds present in the C. gileadensis bark extract for the first time, highlighting the efficacy of UAE as a suitable method for efficiently extracting various groups of phytochemicals from the bark of C. gileadensis.
format Article
author Aiman A., Mokaizh
Nour, Abdurahman Hamid
Rosli, Mohd Yunus
author_facet Aiman A., Mokaizh
Nour, Abdurahman Hamid
Rosli, Mohd Yunus
author_sort Aiman A., Mokaizh
title Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction
title_short Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction
title_full Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction
title_fullStr Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction
title_full_unstemmed Extraction and characterization of phenolic compounds from Commiphora gileadensis bark using ultrasonic-assisted extraction
title_sort extraction and characterization of phenolic compounds from commiphora gileadensis bark using ultrasonic-assisted extraction
publisher Elsevier Ltd
publishDate 2024
url http://umpir.ump.edu.my/id/eprint/42358/1/Extraction%20and%20characterization%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark_ABST.pdf
http://umpir.ump.edu.my/id/eprint/42358/2/Extraction%20and%20characterization%20of%20phenolic%20compounds%20from%20Commiphora%20gileadensis%20bark.pdf
http://umpir.ump.edu.my/id/eprint/42358/
https://doi.org/10.1016/j.prenap.2024.100066
https://doi.org/10.1016/j.prenap.2024.100066
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score 13.235362

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