The synthesis of oxalate-modified pyrite/chitosan as an antibacterial composite

The combination of organic and inorganic components has produced bioactive materials with excellent properties. Chitosan is a widely used organic component that has received recognition as a biocompatible material. In contrast, naturally occurring pyrite has so far received limited exposure as a bio...

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Main Authors: Singh, Rashween Kaur Jagjit, Hui, Khee Chung, Nurul Khusna, Mohd Salleh, Peechmani, Prakash, Farhana, Aziz, Hamidah, Abdullah, Ahmad Nazrul, Rosli, Soraya Sambudi, Nonni Soraya
Format: Article
Language:English
English
Published: ICE Publishing 2023
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/40756/1/The%20synthesis%20of%20oxalate-modified%20pyrite_chitosan.pdf
http://umpir.ump.edu.my/id/eprint/40756/2/The%20synthesis%20of%20oxalate-modi%EF%AC%81ed%20pyrite_chitosan%20as%20an%20antibacterial%20composite_ABS.pdf
http://umpir.ump.edu.my/id/eprint/40756/
https://doi.org/10.1680/jbibn.22.00022
https://doi.org/10.1680/jbibn.22.00022
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spelling my.ump.umpir.407562024-05-28T07:57:06Z http://umpir.ump.edu.my/id/eprint/40756/ The synthesis of oxalate-modified pyrite/chitosan as an antibacterial composite Singh, Rashween Kaur Jagjit Hui, Khee Chung Nurul Khusna, Mohd Salleh Peechmani, Prakash Farhana, Aziz Hamidah, Abdullah Ahmad Nazrul, Rosli Soraya Sambudi, Nonni Soraya QD Chemistry T Technology (General) TA Engineering (General). Civil engineering (General) TP Chemical technology The combination of organic and inorganic components has produced bioactive materials with excellent properties. Chitosan is a widely used organic component that has received recognition as a biocompatible material. In contrast, naturally occurring pyrite has so far received limited exposure as a biomaterial, despite its great antibacterial activity. Hence, the incorporation of pyrite into the chitosan matrix is expected to highlight the usage of pyrite as a bioactive material, particularly in antibacterial response. In this research, chitosan and oxalate-modified pyrite were combined to form beads at wt% pyrite loadings of 1, 3 and 5%. Energy-dispersive X-ray spectroscopy analysis could confirm the loading of pyrite into the bead matrix. The beads exhibit a high water absorption ability. With the addition of pyrite, the absorption of water could increase up to 37% compared with that of blank chitosan beads. The immersion of beads in simulated body fluid shows the bioactivity of beads by formation of apatite. Microbial activity against Escherichia coli and Staphylococcus aureus is exhibited by all composite beads containing oxalate-modified pyrite, particularly by beads containing 5 wt% oxalate-pyrite. ICE Publishing 2023-05-20 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/40756/1/The%20synthesis%20of%20oxalate-modified%20pyrite_chitosan.pdf pdf en http://umpir.ump.edu.my/id/eprint/40756/2/The%20synthesis%20of%20oxalate-modi%EF%AC%81ed%20pyrite_chitosan%20as%20an%20antibacterial%20composite_ABS.pdf Singh, Rashween Kaur Jagjit and Hui, Khee Chung and Nurul Khusna, Mohd Salleh and Peechmani, Prakash and Farhana, Aziz and Hamidah, Abdullah and Ahmad Nazrul, Rosli and Soraya Sambudi, Nonni Soraya (2023) The synthesis of oxalate-modified pyrite/chitosan as an antibacterial composite. Bioinspired, Biomimetic and Nanobiomaterials, 12 (2). pp. 94-103. ISSN 2045-9858. (Published) https://doi.org/10.1680/jbibn.22.00022 https://doi.org/10.1680/jbibn.22.00022
institution Universiti Malaysia Pahang Al-Sultan Abdullah
building UMPSA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang Al-Sultan Abdullah
content_source UMPSA Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
English
topic QD Chemistry
T Technology (General)
TA Engineering (General). Civil engineering (General)
TP Chemical technology
spellingShingle QD Chemistry
T Technology (General)
TA Engineering (General). Civil engineering (General)
TP Chemical technology
Singh, Rashween Kaur Jagjit
Hui, Khee Chung
Nurul Khusna, Mohd Salleh
Peechmani, Prakash
Farhana, Aziz
Hamidah, Abdullah
Ahmad Nazrul, Rosli
Soraya Sambudi, Nonni Soraya
The synthesis of oxalate-modified pyrite/chitosan as an antibacterial composite
description The combination of organic and inorganic components has produced bioactive materials with excellent properties. Chitosan is a widely used organic component that has received recognition as a biocompatible material. In contrast, naturally occurring pyrite has so far received limited exposure as a biomaterial, despite its great antibacterial activity. Hence, the incorporation of pyrite into the chitosan matrix is expected to highlight the usage of pyrite as a bioactive material, particularly in antibacterial response. In this research, chitosan and oxalate-modified pyrite were combined to form beads at wt% pyrite loadings of 1, 3 and 5%. Energy-dispersive X-ray spectroscopy analysis could confirm the loading of pyrite into the bead matrix. The beads exhibit a high water absorption ability. With the addition of pyrite, the absorption of water could increase up to 37% compared with that of blank chitosan beads. The immersion of beads in simulated body fluid shows the bioactivity of beads by formation of apatite. Microbial activity against Escherichia coli and Staphylococcus aureus is exhibited by all composite beads containing oxalate-modified pyrite, particularly by beads containing 5 wt% oxalate-pyrite.
format Article
author Singh, Rashween Kaur Jagjit
Hui, Khee Chung
Nurul Khusna, Mohd Salleh
Peechmani, Prakash
Farhana, Aziz
Hamidah, Abdullah
Ahmad Nazrul, Rosli
Soraya Sambudi, Nonni Soraya
author_facet Singh, Rashween Kaur Jagjit
Hui, Khee Chung
Nurul Khusna, Mohd Salleh
Peechmani, Prakash
Farhana, Aziz
Hamidah, Abdullah
Ahmad Nazrul, Rosli
Soraya Sambudi, Nonni Soraya
author_sort Singh, Rashween Kaur Jagjit
title The synthesis of oxalate-modified pyrite/chitosan as an antibacterial composite
title_short The synthesis of oxalate-modified pyrite/chitosan as an antibacterial composite
title_full The synthesis of oxalate-modified pyrite/chitosan as an antibacterial composite
title_fullStr The synthesis of oxalate-modified pyrite/chitosan as an antibacterial composite
title_full_unstemmed The synthesis of oxalate-modified pyrite/chitosan as an antibacterial composite
title_sort synthesis of oxalate-modified pyrite/chitosan as an antibacterial composite
publisher ICE Publishing
publishDate 2023
url http://umpir.ump.edu.my/id/eprint/40756/1/The%20synthesis%20of%20oxalate-modified%20pyrite_chitosan.pdf
http://umpir.ump.edu.my/id/eprint/40756/2/The%20synthesis%20of%20oxalate-modi%EF%AC%81ed%20pyrite_chitosan%20as%20an%20antibacterial%20composite_ABS.pdf
http://umpir.ump.edu.my/id/eprint/40756/
https://doi.org/10.1680/jbibn.22.00022
https://doi.org/10.1680/jbibn.22.00022
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