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Direct fabrication of glass microfluidic channel using CO2 laser

The design and development of small and compact devices with numerous new functions and vast benefits to the society is steadily receiving global attention. These sophisticated small devices require the production of accurate and intricate micro and nano-scale patterns with different three-dimension...

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Main Authors: Norfazilasari, Yasman, Raja Murfiqah, Raja Mohd Fouzy, Mohd Zairulnizam, Mohd Zawawi
Format: Conference or Workshop Item
Language:English
English
Published: Elsevier Ltd 2023
Subjects:
TS Manufactures
Online Access:http://umpir.ump.edu.my/id/eprint/40297/1/Direct%20fabrication%20of%20glass%20microfluidic%20channel.pdf
http://umpir.ump.edu.my/id/eprint/40297/2/Direct%20fabrication%20of%20glass%20microfluidic%20channel%20using%20CO2%20laser.pdf
http://umpir.ump.edu.my/id/eprint/40297/
https://doi.org/10.1016/j.matpr.2023.11.048
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spelling my.ump.umpir.402972024-02-08T06:24:27Z http://umpir.ump.edu.my/id/eprint/40297/ Direct fabrication of glass microfluidic channel using CO2 laser Norfazilasari, Yasman Raja Murfiqah, Raja Mohd Fouzy Mohd Zairulnizam, Mohd Zawawi TS Manufactures The design and development of small and compact devices with numerous new functions and vast benefits to the society is steadily receiving global attention. These sophisticated small devices require the production of accurate and intricate micro and nano-scale patterns with different three-dimensional (3D) shapes, sizes, and aspect ratios. Microfluidic device or so-called lab-on-a-chip (LOC) is one example of a highly sensitive and compact integrated device capable of detecting multiple analytes, usually used as a diagnostic device. In this study, we demonstrate the feasibility study for direct fabrication of microfluidic channel on transparent optical glass substrate via CO2 direct laser structuring. A custom-built direct laser structuring setup mainly consist of a commercial continuous type of CO2 laser source and glass preheating apparatus is utilized. First, the relationship between the process parameters, mainly the laser scanning speed, number of lasers passes and initial glass preheating temperature to the formation of microchannel of different width, height and shape were established. Then, the form accuracy and the morphology of the microchannels were characterized using laser scanning confocal microscope (LSCM) and surface profiler. Overall, the result reveals that the combination of higher laser power, lower scanning speed and higher number of laser passes promotes the increase of both the width and height of the microchannel. Preheating was found to be necessary for the glass used in this study in avoiding either micro-cracks or bulk glass cracking. Based on the relationship between laser scanning speed and the number of laser passes, a prototype of a microfluidic channel with average width and height of about 235 ± 10 µm and 6 ± 0.3 µm, respectively was successfully fabricated. This study opens an opportunity for further improvement and research for fabrication of crack-free and smooth microfluidic channels using low-cost CO2 laser structuring setup. Elsevier Ltd 2023 Conference or Workshop Item NonPeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/40297/1/Direct%20fabrication%20of%20glass%20microfluidic%20channel.pdf pdf en http://umpir.ump.edu.my/id/eprint/40297/2/Direct%20fabrication%20of%20glass%20microfluidic%20channel%20using%20CO2%20laser.pdf Norfazilasari, Yasman and Raja Murfiqah, Raja Mohd Fouzy and Mohd Zairulnizam, Mohd Zawawi (2023) Direct fabrication of glass microfluidic channel using CO2 laser. In: Materials Today: Proceedings. 2nd International Symposium on Advanced Functional Materials , Feb 16, 2023 - Feb 16, 2023 , Kuala Lumpur, Malaysia. . ISSN 2214-7853 (In Press / Online First) https://doi.org/10.1016/j.matpr.2023.11.048
institution Universiti Malaysia Pahang Al-Sultan Abdullah
building UMPSA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang Al-Sultan Abdullah
content_source UMPSA Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
English
topic TS Manufactures
spellingShingle TS Manufactures
Norfazilasari, Yasman
Raja Murfiqah, Raja Mohd Fouzy
Mohd Zairulnizam, Mohd Zawawi
Direct fabrication of glass microfluidic channel using CO2 laser
description The design and development of small and compact devices with numerous new functions and vast benefits to the society is steadily receiving global attention. These sophisticated small devices require the production of accurate and intricate micro and nano-scale patterns with different three-dimensional (3D) shapes, sizes, and aspect ratios. Microfluidic device or so-called lab-on-a-chip (LOC) is one example of a highly sensitive and compact integrated device capable of detecting multiple analytes, usually used as a diagnostic device. In this study, we demonstrate the feasibility study for direct fabrication of microfluidic channel on transparent optical glass substrate via CO2 direct laser structuring. A custom-built direct laser structuring setup mainly consist of a commercial continuous type of CO2 laser source and glass preheating apparatus is utilized. First, the relationship between the process parameters, mainly the laser scanning speed, number of lasers passes and initial glass preheating temperature to the formation of microchannel of different width, height and shape were established. Then, the form accuracy and the morphology of the microchannels were characterized using laser scanning confocal microscope (LSCM) and surface profiler. Overall, the result reveals that the combination of higher laser power, lower scanning speed and higher number of laser passes promotes the increase of both the width and height of the microchannel. Preheating was found to be necessary for the glass used in this study in avoiding either micro-cracks or bulk glass cracking. Based on the relationship between laser scanning speed and the number of laser passes, a prototype of a microfluidic channel with average width and height of about 235 ± 10 µm and 6 ± 0.3 µm, respectively was successfully fabricated. This study opens an opportunity for further improvement and research for fabrication of crack-free and smooth microfluidic channels using low-cost CO2 laser structuring setup.
format Conference or Workshop Item
author Norfazilasari, Yasman
Raja Murfiqah, Raja Mohd Fouzy
Mohd Zairulnizam, Mohd Zawawi
author_facet Norfazilasari, Yasman
Raja Murfiqah, Raja Mohd Fouzy
Mohd Zairulnizam, Mohd Zawawi
author_sort Norfazilasari, Yasman
title Direct fabrication of glass microfluidic channel using CO2 laser
title_short Direct fabrication of glass microfluidic channel using CO2 laser
title_full Direct fabrication of glass microfluidic channel using CO2 laser
title_fullStr Direct fabrication of glass microfluidic channel using CO2 laser
title_full_unstemmed Direct fabrication of glass microfluidic channel using CO2 laser
title_sort direct fabrication of glass microfluidic channel using co2 laser
publisher Elsevier Ltd
publishDate 2023
url http://umpir.ump.edu.my/id/eprint/40297/1/Direct%20fabrication%20of%20glass%20microfluidic%20channel.pdf
http://umpir.ump.edu.my/id/eprint/40297/2/Direct%20fabrication%20of%20glass%20microfluidic%20channel%20using%20CO2%20laser.pdf
http://umpir.ump.edu.my/id/eprint/40297/
https://doi.org/10.1016/j.matpr.2023.11.048
_version_ 1822924139754684416
score 13.23648

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