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Modeling the effect of different locations of carotid atherosclerosis on hemodynamics parameters

Carotid atherosclerosis is a potentially fatal diseases caused by plaques buildup in arteries that deliver blood to the brain. Over the years, this pathological condition particularly the stenosis size severity has been studied, and computational fluid dynamics has played an essential role in invest...

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主要な著者: A. Fahmi Huwaidi, M. Noor, Nasrul Hadi, Johari
フォーマット: Conference or Workshop Item
言語:English
English
出版事項: Springer 2022
主題:
R Medicine (General)
T Technology (General)
オンライン･アクセス:http://umpir.ump.edu.my/id/eprint/37899/1/Modeling%20the%20effect%20of%20different%20locations%20of%20carotid.pdf
http://umpir.ump.edu.my/id/eprint/37899/2/Modeling%20the%20effect%20of%20different%20locations%20of%20carotid%20atherosclerosis%20on%20hemodynamics%20.pdf
http://umpir.ump.edu.my/id/eprint/37899/
https://doi.org/10.1007/978-981-19-1577-2_45
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spelling my.ump.umpir.378992023-07-12T07:54:25Z http://umpir.ump.edu.my/id/eprint/37899/ Modeling the effect of different locations of carotid atherosclerosis on hemodynamics parameters A. Fahmi Huwaidi, M. Noor Nasrul Hadi, Johari R Medicine (General) T Technology (General) Carotid atherosclerosis is a potentially fatal diseases caused by plaques buildup in arteries that deliver blood to the brain. Over the years, this pathological condition particularly the stenosis size severity has been studied, and computational fluid dynamics has played an essential role in investigating the blood flow behavior. However, the study on the effect of stenosis location especially at the area of bifurcation is still lacking. This study aims to investigate which stenosis location would cause higher risk factor and high flow disturbance to the blood flow. The area susceptible for atherosclerosis is usually at the carotid bifurcation where common carotid artery (CCA) is bifurcated into internal carotid artery (ICA) and external carotid artery (ECA). The computational simulations were performed using idealized geometry of carotid artery with different locations of stenoses. Type I, II and III stenoses were grouped according to the most common type and location stenosis. The results show that the Type I geometry with stenosis extended toward the ICA had higher possibility for the atherosclerosis plaque to grow. Velocity profiles and low wall shear stress contours predicted more complex helical and recirculation blood flow at post-stenotic region of Type I as compared to the other two. The findings indicate that atherosclerosis plaque in the ICA could provide higher risk to the patient and immediate medical treatment shall be required. Springer 2022 Conference or Workshop Item PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/37899/1/Modeling%20the%20effect%20of%20different%20locations%20of%20carotid.pdf pdf en http://umpir.ump.edu.my/id/eprint/37899/2/Modeling%20the%20effect%20of%20different%20locations%20of%20carotid%20atherosclerosis%20on%20hemodynamics%20.pdf A. Fahmi Huwaidi, M. Noor and Nasrul Hadi, Johari (2022) Modeling the effect of different locations of carotid atherosclerosis on hemodynamics parameters. In: 6th International Conference on Mechanical Engineering Research, ICMER 2021, 26 - 27 October 2021 , Virtual Online. pp. 615-627., 882. ISSN 1876-1100 ISBN 9789811915772 https://doi.org/10.1007/978-981-19-1577-2_45
institution Universiti Malaysia Pahang Al-Sultan Abdullah
building UMPSA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang Al-Sultan Abdullah
content_source UMPSA Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
English
topic R Medicine (General)
T Technology (General)
spellingShingle R Medicine (General)
T Technology (General)
A. Fahmi Huwaidi, M. Noor
Nasrul Hadi, Johari
Modeling the effect of different locations of carotid atherosclerosis on hemodynamics parameters
description Carotid atherosclerosis is a potentially fatal diseases caused by plaques buildup in arteries that deliver blood to the brain. Over the years, this pathological condition particularly the stenosis size severity has been studied, and computational fluid dynamics has played an essential role in investigating the blood flow behavior. However, the study on the effect of stenosis location especially at the area of bifurcation is still lacking. This study aims to investigate which stenosis location would cause higher risk factor and high flow disturbance to the blood flow. The area susceptible for atherosclerosis is usually at the carotid bifurcation where common carotid artery (CCA) is bifurcated into internal carotid artery (ICA) and external carotid artery (ECA). The computational simulations were performed using idealized geometry of carotid artery with different locations of stenoses. Type I, II and III stenoses were grouped according to the most common type and location stenosis. The results show that the Type I geometry with stenosis extended toward the ICA had higher possibility for the atherosclerosis plaque to grow. Velocity profiles and low wall shear stress contours predicted more complex helical and recirculation blood flow at post-stenotic region of Type I as compared to the other two. The findings indicate that atherosclerosis plaque in the ICA could provide higher risk to the patient and immediate medical treatment shall be required.
format Conference or Workshop Item
author A. Fahmi Huwaidi, M. Noor
Nasrul Hadi, Johari
author_facet A. Fahmi Huwaidi, M. Noor
Nasrul Hadi, Johari
author_sort A. Fahmi Huwaidi, M. Noor
title Modeling the effect of different locations of carotid atherosclerosis on hemodynamics parameters
title_short Modeling the effect of different locations of carotid atherosclerosis on hemodynamics parameters
title_full Modeling the effect of different locations of carotid atherosclerosis on hemodynamics parameters
title_fullStr Modeling the effect of different locations of carotid atherosclerosis on hemodynamics parameters
title_full_unstemmed Modeling the effect of different locations of carotid atherosclerosis on hemodynamics parameters
title_sort modeling the effect of different locations of carotid atherosclerosis on hemodynamics parameters
publisher Springer
publishDate 2022
url http://umpir.ump.edu.my/id/eprint/37899/1/Modeling%20the%20effect%20of%20different%20locations%20of%20carotid.pdf
http://umpir.ump.edu.my/id/eprint/37899/2/Modeling%20the%20effect%20of%20different%20locations%20of%20carotid%20atherosclerosis%20on%20hemodynamics%20.pdf
http://umpir.ump.edu.my/id/eprint/37899/
https://doi.org/10.1007/978-981-19-1577-2_45
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score 13.251813

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