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Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted combretum indicum leaves

Combretum Indicum (CI), which contains numerous bioactive compounds, has been used in traditional medicine for a variety of reasons, including the treatment of skin conditions. This study investigates the antioxidant and anti-tyrosinase activities of CI leaves extracted using different surfactants (...

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Main Authors: Thanaseelan, Tanesha, Nurul Hidayu, Daud, Nurul Sahirah, Imam, Rajaletchumy, Veloo Kutty
Format: Conference or Workshop Item
Language:English
English
Published: 2022
Subjects:
QD Chemistry
T Technology (General)
TA Engineering (General). Civil engineering (General)
TP Chemical technology
Online Access:http://umpir.ump.edu.my/id/eprint/37180/1/Evaluation%20of%20antioxidant%20and%20anti-tyrosinase%20activities%20of%20surfactant%20and%20alcohol%20extracted%20combretum%20indicum%20leaves.pdf
http://umpir.ump.edu.my/id/eprint/37180/7/NCON-PGR%202022_196%20Evaluation%20of%20antioxidant%20and%20anti-tyrosinase%20activities%20of%20surfactant%20and%20alcohol%20extracted%20Combretum%20Indicum%20leaves.pdf
http://umpir.ump.edu.my/id/eprint/37180/
https://ncon-pgr.ump.edu.my/index.php/en/?option=com_fileman&view=file&routed=1&name=E-BOOK%20NCON%202022%20.pdf&folder=E-BOOK%20NCON%202022&container=fileman-files
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spelling my.ump.umpir.371802023-11-15T06:06:25Z http://umpir.ump.edu.my/id/eprint/37180/ Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted combretum indicum leaves Thanaseelan, Tanesha Nurul Hidayu, Daud Nurul Sahirah, Imam Rajaletchumy, Veloo Kutty QD Chemistry T Technology (General) TA Engineering (General). Civil engineering (General) TP Chemical technology Combretum Indicum (CI), which contains numerous bioactive compounds, has been used in traditional medicine for a variety of reasons, including the treatment of skin conditions. This study investigates the antioxidant and anti-tyrosinase activities of CI leaves extracted using different surfactants (Triton X-100 and Vitamin E TPGS) at concentrations of 1%, 2%, and 3%, as well as various alcohol solvents (acetone, methanol, and ethanol) at concentrations of 50%, 70%, and 90%. The antioxidant activity of the extracts has been evaluated using Total Phenolic Content (TPC) and 2,2-diphenyl-1-picrylhydrazyl (DPPH), while the anti-tyrosinase activity was assessed through a mushroom tyrosinase inhibition assay. Prior to analysis, CI leaves had been macerated, extracted, and freeze-dried. The research established that ethanol at a concentration of 50% is the optimum solvent to extract CI leaves, as it demonstrated good antioxidant and anti-tyrosinase action with a high percentage of yield and total phenolic content. As a result, the outcomes of this study contribute to a better understanding of the potential applications of CI leaf extract in cosmetics, notably in the treatment of oxidative stress and hyperpigmentation. Further study and development in this field could lead to the creation of effective and natural cosmetic products produced from CI leaves that have antioxidant and anti-tyrosinase effects. 2022-11-15 Conference or Workshop Item PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/37180/1/Evaluation%20of%20antioxidant%20and%20anti-tyrosinase%20activities%20of%20surfactant%20and%20alcohol%20extracted%20combretum%20indicum%20leaves.pdf pdf en http://umpir.ump.edu.my/id/eprint/37180/7/NCON-PGR%202022_196%20Evaluation%20of%20antioxidant%20and%20anti-tyrosinase%20activities%20of%20surfactant%20and%20alcohol%20extracted%20Combretum%20Indicum%20leaves.pdf Thanaseelan, Tanesha and Nurul Hidayu, Daud and Nurul Sahirah, Imam and Rajaletchumy, Veloo Kutty (2022) Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted combretum indicum leaves. In: The 6th National Conference for Postgraduate Research (NCON-PGR 2022), 15 November 2022 , Virtual Conference, Universiti Malaysia Pahang, Malaysia. p. 191.. https://ncon-pgr.ump.edu.my/index.php/en/?option=com_fileman&view=file&routed=1&name=E-BOOK%20NCON%202022%20.pdf&folder=E-BOOK%20NCON%202022&container=fileman-files
institution Universiti Malaysia Pahang Al-Sultan Abdullah
building UMPSA Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang Al-Sultan Abdullah
content_source UMPSA Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
English
topic QD Chemistry
T Technology (General)
TA Engineering (General). Civil engineering (General)
TP Chemical technology
spellingShingle QD Chemistry
T Technology (General)
TA Engineering (General). Civil engineering (General)
TP Chemical technology
Thanaseelan, Tanesha
Nurul Hidayu, Daud
Nurul Sahirah, Imam
Rajaletchumy, Veloo Kutty
Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted combretum indicum leaves
description Combretum Indicum (CI), which contains numerous bioactive compounds, has been used in traditional medicine for a variety of reasons, including the treatment of skin conditions. This study investigates the antioxidant and anti-tyrosinase activities of CI leaves extracted using different surfactants (Triton X-100 and Vitamin E TPGS) at concentrations of 1%, 2%, and 3%, as well as various alcohol solvents (acetone, methanol, and ethanol) at concentrations of 50%, 70%, and 90%. The antioxidant activity of the extracts has been evaluated using Total Phenolic Content (TPC) and 2,2-diphenyl-1-picrylhydrazyl (DPPH), while the anti-tyrosinase activity was assessed through a mushroom tyrosinase inhibition assay. Prior to analysis, CI leaves had been macerated, extracted, and freeze-dried. The research established that ethanol at a concentration of 50% is the optimum solvent to extract CI leaves, as it demonstrated good antioxidant and anti-tyrosinase action with a high percentage of yield and total phenolic content. As a result, the outcomes of this study contribute to a better understanding of the potential applications of CI leaf extract in cosmetics, notably in the treatment of oxidative stress and hyperpigmentation. Further study and development in this field could lead to the creation of effective and natural cosmetic products produced from CI leaves that have antioxidant and anti-tyrosinase effects.
format Conference or Workshop Item
author Thanaseelan, Tanesha
Nurul Hidayu, Daud
Nurul Sahirah, Imam
Rajaletchumy, Veloo Kutty
author_facet Thanaseelan, Tanesha
Nurul Hidayu, Daud
Nurul Sahirah, Imam
Rajaletchumy, Veloo Kutty
author_sort Thanaseelan, Tanesha
title Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted combretum indicum leaves
title_short Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted combretum indicum leaves
title_full Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted combretum indicum leaves
title_fullStr Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted combretum indicum leaves
title_full_unstemmed Evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted combretum indicum leaves
title_sort evaluation of antioxidant and anti-tyrosinase activities of surfactant and alcohol extracted combretum indicum leaves
publishDate 2022
url http://umpir.ump.edu.my/id/eprint/37180/1/Evaluation%20of%20antioxidant%20and%20anti-tyrosinase%20activities%20of%20surfactant%20and%20alcohol%20extracted%20combretum%20indicum%20leaves.pdf
http://umpir.ump.edu.my/id/eprint/37180/7/NCON-PGR%202022_196%20Evaluation%20of%20antioxidant%20and%20anti-tyrosinase%20activities%20of%20surfactant%20and%20alcohol%20extracted%20Combretum%20Indicum%20leaves.pdf
http://umpir.ump.edu.my/id/eprint/37180/
https://ncon-pgr.ump.edu.my/index.php/en/?option=com_fileman&view=file&routed=1&name=E-BOOK%20NCON%202022%20.pdf&folder=E-BOOK%20NCON%202022&container=fileman-files
_version_ 1822923377312006144
score 13.235796

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