Autoimmune Diseases and Gut Symbionts: The Unpopular Liaison
In the past few years, compelling data have shown the potential crosstalk between dysbiosis of gut microbiota (GM) and impairment of systemic immune system. Since then, ideas on how GM partake in autoimmune conditions was put forward. Although genetic variability have been proven to contribute tow...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Universiti Putra Malaysia
2019
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/29961/7/Autoimmune%20Diseases%20and%20Gut%20Symbionts.pdf http://umpir.ump.edu.my/id/eprint/29961/ https://medic.upm.edu.my/upload/dokumen/2019121815324125_MJMHS_0412.pdf |
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| Summary: | In the past few years, compelling data have shown the potential crosstalk between dysbiosis of gut microbiota (GM)
and impairment of systemic immune system. Since then, ideas on how GM partake in autoimmune conditions was
put forward. Although genetic variability have been proven to contribute towards the pathogenesis of autoimmune
conditions, epigenetics control have gained interest among researchers. Current review highlights the crosstalk between autoimmune conditions and GM and its potential regulatory mechanisms. Convincing data from existing
literature help in paving ways for more well-defined species in the future studies. The studies should focus on identifying the distinct species involve in different types of autoimmune diseases and their definitive role in autoimmunity.
Ultimately, these data can be used for the advancement of therapeutic approach in personalized medicine. |
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