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Enhanced sensitivity of microring resonator-based sensors using the finite difference time domain method to detect glucose levels for diabetes monitoring

The properties of light and its interaction with biological analytes have made it possible to design sophisticated and reliable optical-based biomedical sensors. In this paper, we report the simulation, design, and fabrication of microring resonator (MRR)-based sensors for the detection of diabetic...

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Main Authors: Hasanah, Lilik, Nugroho, Harbi Setyo, Chandra, Wulandari, Budi, Mulyanti, Berhanuddin, Dilla Duryha, Mohamad Hazwan, Haron, Susthitha, Menon P., Ahmad Rifqi, Md. Zain, Hamidah, Ida, Khairurrijal, Khairurrijal, R., Mamat
Format: Article
Language:English
Published: MDPI 2019
Subjects:
TJ Mechanical engineering and machinery
Online Access:http://umpir.ump.edu.my/id/eprint/29826/1/2.%20Enhanced%20Sensitivity%20of%20Microring%20Resonator-Based%20Sensors%20Using%20the%20Finite%20Difference.pdf
http://umpir.ump.edu.my/id/eprint/29826/
https://doi.org/10.3390/app10124191
https://doi.org/10.3390/app10124191
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spelling my.ump.umpir.298262020-11-13T02:39:15Z http://umpir.ump.edu.my/id/eprint/29826/ Enhanced sensitivity of microring resonator-based sensors using the finite difference time domain method to detect glucose levels for diabetes monitoring Hasanah, Lilik Nugroho, Harbi Setyo Chandra, Wulandari Budi, Mulyanti Berhanuddin, Dilla Duryha Mohamad Hazwan, Haron Susthitha, Menon P. Ahmad Rifqi, Md. Zain Hamidah, Ida Khairurrijal, Khairurrijal R., Mamat TJ Mechanical engineering and machinery The properties of light and its interaction with biological analytes have made it possible to design sophisticated and reliable optical-based biomedical sensors. In this paper, we report the simulation, design, and fabrication of microring resonator (MRR)-based sensors for the detection of diabetic glucose levels. Electron Beam Lithography (EBL) with 1:1 hydrogen silsesquioxane (HSQ) negative tone resist were used to fabricate MRR on a Silicon-on-Insulator (SOI) platform. Scanning Electron Microscopy (SEM) was then used to characterize the morphology of the MRR device. The full-width at half-maximum (FWHM) and quality factors of MRR were obtained by using a tunable laser source (TLS) and optical spectrum analyzer (OSA). In this paper, the three-dimensional Finite Difference Time Domain (3D FDTD) approach has been used to simulate the proposed design. The simulation results show an accurate approximation with the experimental results. Next, the sensitivity of MRR-based sensors to detect glucose levels is obtained. The sensitivity value for glucose level detection in the range 0% to 18% is 69.44 nm/RIU. This proved that our MRR design has a great potential as a sensor to detect diabetic glucose levels. MDPI 2019 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/29826/1/2.%20Enhanced%20Sensitivity%20of%20Microring%20Resonator-Based%20Sensors%20Using%20the%20Finite%20Difference.pdf Hasanah, Lilik and Nugroho, Harbi Setyo and Chandra, Wulandari and Budi, Mulyanti and Berhanuddin, Dilla Duryha and Mohamad Hazwan, Haron and Susthitha, Menon P. and Ahmad Rifqi, Md. Zain and Hamidah, Ida and Khairurrijal, Khairurrijal and R., Mamat (2019) Enhanced sensitivity of microring resonator-based sensors using the finite difference time domain method to detect glucose levels for diabetes monitoring. Applied Sciences, 10 (12). pp. 1-12. ISSN 2076-3417 https://doi.org/10.3390/app10124191 https://doi.org/10.3390/app10124191
institution Universiti Malaysia Pahang
building UMP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang
content_source UMP Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
topic TJ Mechanical engineering and machinery
spellingShingle TJ Mechanical engineering and machinery
Hasanah, Lilik
Nugroho, Harbi Setyo
Chandra, Wulandari
Budi, Mulyanti
Berhanuddin, Dilla Duryha
Mohamad Hazwan, Haron
Susthitha, Menon P.
Ahmad Rifqi, Md. Zain
Hamidah, Ida
Khairurrijal, Khairurrijal
R., Mamat
Enhanced sensitivity of microring resonator-based sensors using the finite difference time domain method to detect glucose levels for diabetes monitoring
description The properties of light and its interaction with biological analytes have made it possible to design sophisticated and reliable optical-based biomedical sensors. In this paper, we report the simulation, design, and fabrication of microring resonator (MRR)-based sensors for the detection of diabetic glucose levels. Electron Beam Lithography (EBL) with 1:1 hydrogen silsesquioxane (HSQ) negative tone resist were used to fabricate MRR on a Silicon-on-Insulator (SOI) platform. Scanning Electron Microscopy (SEM) was then used to characterize the morphology of the MRR device. The full-width at half-maximum (FWHM) and quality factors of MRR were obtained by using a tunable laser source (TLS) and optical spectrum analyzer (OSA). In this paper, the three-dimensional Finite Difference Time Domain (3D FDTD) approach has been used to simulate the proposed design. The simulation results show an accurate approximation with the experimental results. Next, the sensitivity of MRR-based sensors to detect glucose levels is obtained. The sensitivity value for glucose level detection in the range 0% to 18% is 69.44 nm/RIU. This proved that our MRR design has a great potential as a sensor to detect diabetic glucose levels.
format Article
author Hasanah, Lilik
Nugroho, Harbi Setyo
Chandra, Wulandari
Budi, Mulyanti
Berhanuddin, Dilla Duryha
Mohamad Hazwan, Haron
Susthitha, Menon P.
Ahmad Rifqi, Md. Zain
Hamidah, Ida
Khairurrijal, Khairurrijal
R., Mamat
author_facet Hasanah, Lilik
Nugroho, Harbi Setyo
Chandra, Wulandari
Budi, Mulyanti
Berhanuddin, Dilla Duryha
Mohamad Hazwan, Haron
Susthitha, Menon P.
Ahmad Rifqi, Md. Zain
Hamidah, Ida
Khairurrijal, Khairurrijal
R., Mamat
author_sort Hasanah, Lilik
title Enhanced sensitivity of microring resonator-based sensors using the finite difference time domain method to detect glucose levels for diabetes monitoring
title_short Enhanced sensitivity of microring resonator-based sensors using the finite difference time domain method to detect glucose levels for diabetes monitoring
title_full Enhanced sensitivity of microring resonator-based sensors using the finite difference time domain method to detect glucose levels for diabetes monitoring
title_fullStr Enhanced sensitivity of microring resonator-based sensors using the finite difference time domain method to detect glucose levels for diabetes monitoring
title_full_unstemmed Enhanced sensitivity of microring resonator-based sensors using the finite difference time domain method to detect glucose levels for diabetes monitoring
title_sort enhanced sensitivity of microring resonator-based sensors using the finite difference time domain method to detect glucose levels for diabetes monitoring
publisher MDPI
publishDate 2019
url http://umpir.ump.edu.my/id/eprint/29826/1/2.%20Enhanced%20Sensitivity%20of%20Microring%20Resonator-Based%20Sensors%20Using%20the%20Finite%20Difference.pdf
http://umpir.ump.edu.my/id/eprint/29826/
https://doi.org/10.3390/app10124191
https://doi.org/10.3390/app10124191
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score 13.211869

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