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Bredigite Reinforced Electrospun Nanofibers for Bone Tissue Engineering

In this study, bredigite nanoparticles were treated with an organosilane coupling agent to enhance its dispersability and compatibility with polymers. The polyhydroxybutyrate-co-hydroxyvaletare (PHBV) nanofibrous scaffolds containing treated bredigite (T-BR) nanoparticles were developed using electr...

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Main Authors: Monireh, Kouhi, Mohammadhossein, Fathi, Venugopal, Jayarama Reddy, Seeram, Ramakrishna
Format: Article
Language:English
Published: Elsevier 2019
Subjects:
R Medicine (General)
Online Access:http://umpir.ump.edu.my/id/eprint/29678/1/Materials%20Today%20Proceedings%207%202019%20449%E2%80%93454.pdf
http://umpir.ump.edu.my/id/eprint/29678/
http://www.sciencedirect.com
https://doi.org/10.1016/j.matpr.2018.11.108
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spelling my.ump.umpir.296782020-10-22T02:53:43Z http://umpir.ump.edu.my/id/eprint/29678/ Bredigite Reinforced Electrospun Nanofibers for Bone Tissue Engineering Monireh, Kouhi Mohammadhossein, Fathi Venugopal, Jayarama Reddy Seeram, Ramakrishna R Medicine (General) In this study, bredigite nanoparticles were treated with an organosilane coupling agent to enhance its dispersability and compatibility with polymers. The polyhydroxybutyrate-co-hydroxyvaletare (PHBV) nanofibrous scaffolds containing treated bredigite (T-BR) nanoparticles were developed using electrospinning technique. It was found that pre-treating of bredigite was effective in enhancing nanoparticles dispersion both in the solution and in the PHBV matrix. Mechanical properties of the PHBV nanofibrous scaffolds were remarkably improved by incorporation of T-BR nanoparticles. The results also demonstrated that bioactivity and biodegradability rate of PHBV nanofibrous scaffolds were greatly altered by addition of BR and T-BR nanoparticles. Our study demonstrated that incorporation of T-BR nanoparticles within PHBV nanofibers may improve its mechanical performance and bioactivity, making it more appropriate materials for bone tissue engineering applications. Elsevier 2019 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/29678/1/Materials%20Today%20Proceedings%207%202019%20449%E2%80%93454.pdf Monireh, Kouhi and Mohammadhossein, Fathi and Venugopal, Jayarama Reddy and Seeram, Ramakrishna (2019) Bredigite Reinforced Electrospun Nanofibers for Bone Tissue Engineering. Materials Today: Proceedings, 7. pp. 449-454. http://www.sciencedirect.com https://doi.org/10.1016/j.matpr.2018.11.108
institution Universiti Malaysia Pahang
building UMP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang
content_source UMP Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Monireh, Kouhi
Mohammadhossein, Fathi
Venugopal, Jayarama Reddy
Seeram, Ramakrishna
Bredigite Reinforced Electrospun Nanofibers for Bone Tissue Engineering
description In this study, bredigite nanoparticles were treated with an organosilane coupling agent to enhance its dispersability and compatibility with polymers. The polyhydroxybutyrate-co-hydroxyvaletare (PHBV) nanofibrous scaffolds containing treated bredigite (T-BR) nanoparticles were developed using electrospinning technique. It was found that pre-treating of bredigite was effective in enhancing nanoparticles dispersion both in the solution and in the PHBV matrix. Mechanical properties of the PHBV nanofibrous scaffolds were remarkably improved by incorporation of T-BR nanoparticles. The results also demonstrated that bioactivity and biodegradability rate of PHBV nanofibrous scaffolds were greatly altered by addition of BR and T-BR nanoparticles. Our study demonstrated that incorporation of T-BR nanoparticles within PHBV nanofibers may improve its mechanical performance and bioactivity, making it more appropriate materials for bone tissue engineering applications.
format Article
author Monireh, Kouhi
Mohammadhossein, Fathi
Venugopal, Jayarama Reddy
Seeram, Ramakrishna
author_facet Monireh, Kouhi
Mohammadhossein, Fathi
Venugopal, Jayarama Reddy
Seeram, Ramakrishna
author_sort Monireh, Kouhi
title Bredigite Reinforced Electrospun Nanofibers for Bone Tissue Engineering
title_short Bredigite Reinforced Electrospun Nanofibers for Bone Tissue Engineering
title_full Bredigite Reinforced Electrospun Nanofibers for Bone Tissue Engineering
title_fullStr Bredigite Reinforced Electrospun Nanofibers for Bone Tissue Engineering
title_full_unstemmed Bredigite Reinforced Electrospun Nanofibers for Bone Tissue Engineering
title_sort bredigite reinforced electrospun nanofibers for bone tissue engineering
publisher Elsevier
publishDate 2019
url http://umpir.ump.edu.my/id/eprint/29678/1/Materials%20Today%20Proceedings%207%202019%20449%E2%80%93454.pdf
http://umpir.ump.edu.my/id/eprint/29678/
http://www.sciencedirect.com
https://doi.org/10.1016/j.matpr.2018.11.108
_version_ 1681489643805081600
score 13.211869

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