Extraction of bioactive compounds (mangiferin) from mahkota dewa fruits using subcritical water extraction process

Mahkota Dewa or scientifically known as Phaleria Macrocarpa is a popular herbal plant in Indonesia and Malaysia. The bioactive ingredient in this plant process antihistamine, antioxidant, anti-cancer compound. In this work, experimental studies were performed using subcritical water extraction proce...

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Main Author: Ummi Najihah, Md Hashim
Format: Undergraduates Project Papers
Language:English
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Published: 2016
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Online Access:http://umpir.ump.edu.my/id/eprint/22628/1/Extraction%20of%20bioactive%20compounds%20%28mangiferin%29%20from%20mahkota%20dewa%20fruits%20using%20subcritical%20water%20extraction%20process%20-%20Table%20of%20contents.pdf
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spelling my.ump.umpir.226282021-06-01T07:21:06Z http://umpir.ump.edu.my/id/eprint/22628/ Extraction of bioactive compounds (mangiferin) from mahkota dewa fruits using subcritical water extraction process Ummi Najihah, Md Hashim TP Chemical technology Mahkota Dewa or scientifically known as Phaleria Macrocarpa is a popular herbal plant in Indonesia and Malaysia. The bioactive ingredient in this plant process antihistamine, antioxidant, anti-cancer compound. In this work, experimental studies were performed using subcritical water extraction process to extract the bioactive compound namely mangiferin from Mahkota Dewa fruits. The effect of process parameters which are solid to solvent ratios (30, 40, 50, 60, and 70 g/L), temperature (50, 75, 100, 125, 150 °C) and extraction time (3, 4, 5, 6, 7 h) on the extraction yields were investigated. The extraction yields were analysed and characterised using high performance liquid chromatography (HPLC) and 1,1-Diphenyl-2-picryl hydrazyl (DPPH) assay method, respectively. The highest mangiferin yield is 3.2027w/w % were obtained at 60 g/L of solid to solvent ratio, 100 °C of extraction temperature and 5 h of extraction time. The highest of antioxidant activity is 86.5377 % were obtained at 60 g/L of solid to solvent ratio, 125 °C of extraction temperature, 5 h of extraction time. Antioxidant is defined as a substance which significantly delays or inhibits oxidant process. The high value of antioxidant was obtained from the highest value of DPPH since the remaining DPPH in sample acts free radicals were increased in reactivity of unpaired electron and allowed the development of tissues damage in living organisms. 2016-12 Undergraduates Project Papers NonPeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/22628/1/Extraction%20of%20bioactive%20compounds%20%28mangiferin%29%20from%20mahkota%20dewa%20fruits%20using%20subcritical%20water%20extraction%20process%20-%20Table%20of%20contents.pdf pdf en http://umpir.ump.edu.my/id/eprint/22628/2/Extraction%20of%20bioactive%20compounds%20%28mangiferin%29%20from%20mahkota%20dewa%20fruits%20using%20subcritical%20water%20extraction%20process%20-%20Abstract.pdf pdf en http://umpir.ump.edu.my/id/eprint/22628/3/Extraction%20of%20bioactive%20compounds%20%28mangiferin%29%20from%20mahkota%20dewa%20fruits%20using%20subcritical%20water%20extraction%20process%20-%20Chapter%201.pdf pdf en http://umpir.ump.edu.my/id/eprint/22628/4/Extraction%20of%20bioactive%20compounds%20%28mangiferin%29%20from%20mahkota%20dewa%20fruits%20using%20subcritical%20water%20extraction%20process%20-%20References.pdf Ummi Najihah, Md Hashim (2016) Extraction of bioactive compounds (mangiferin) from mahkota dewa fruits using subcritical water extraction process. Faculty of Chemical & Natural Resources Engineering, Universiti Malaysia Pahang.
institution Universiti Malaysia Pahang
building UMP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang
content_source UMP Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
English
English
English
topic TP Chemical technology
spellingShingle TP Chemical technology
Ummi Najihah, Md Hashim
Extraction of bioactive compounds (mangiferin) from mahkota dewa fruits using subcritical water extraction process
description Mahkota Dewa or scientifically known as Phaleria Macrocarpa is a popular herbal plant in Indonesia and Malaysia. The bioactive ingredient in this plant process antihistamine, antioxidant, anti-cancer compound. In this work, experimental studies were performed using subcritical water extraction process to extract the bioactive compound namely mangiferin from Mahkota Dewa fruits. The effect of process parameters which are solid to solvent ratios (30, 40, 50, 60, and 70 g/L), temperature (50, 75, 100, 125, 150 °C) and extraction time (3, 4, 5, 6, 7 h) on the extraction yields were investigated. The extraction yields were analysed and characterised using high performance liquid chromatography (HPLC) and 1,1-Diphenyl-2-picryl hydrazyl (DPPH) assay method, respectively. The highest mangiferin yield is 3.2027w/w % were obtained at 60 g/L of solid to solvent ratio, 100 °C of extraction temperature and 5 h of extraction time. The highest of antioxidant activity is 86.5377 % were obtained at 60 g/L of solid to solvent ratio, 125 °C of extraction temperature, 5 h of extraction time. Antioxidant is defined as a substance which significantly delays or inhibits oxidant process. The high value of antioxidant was obtained from the highest value of DPPH since the remaining DPPH in sample acts free radicals were increased in reactivity of unpaired electron and allowed the development of tissues damage in living organisms.
format Undergraduates Project Papers
author Ummi Najihah, Md Hashim
author_facet Ummi Najihah, Md Hashim
author_sort Ummi Najihah, Md Hashim
title Extraction of bioactive compounds (mangiferin) from mahkota dewa fruits using subcritical water extraction process
title_short Extraction of bioactive compounds (mangiferin) from mahkota dewa fruits using subcritical water extraction process
title_full Extraction of bioactive compounds (mangiferin) from mahkota dewa fruits using subcritical water extraction process
title_fullStr Extraction of bioactive compounds (mangiferin) from mahkota dewa fruits using subcritical water extraction process
title_full_unstemmed Extraction of bioactive compounds (mangiferin) from mahkota dewa fruits using subcritical water extraction process
title_sort extraction of bioactive compounds (mangiferin) from mahkota dewa fruits using subcritical water extraction process
publishDate 2016
url http://umpir.ump.edu.my/id/eprint/22628/1/Extraction%20of%20bioactive%20compounds%20%28mangiferin%29%20from%20mahkota%20dewa%20fruits%20using%20subcritical%20water%20extraction%20process%20-%20Table%20of%20contents.pdf
http://umpir.ump.edu.my/id/eprint/22628/2/Extraction%20of%20bioactive%20compounds%20%28mangiferin%29%20from%20mahkota%20dewa%20fruits%20using%20subcritical%20water%20extraction%20process%20-%20Abstract.pdf
http://umpir.ump.edu.my/id/eprint/22628/3/Extraction%20of%20bioactive%20compounds%20%28mangiferin%29%20from%20mahkota%20dewa%20fruits%20using%20subcritical%20water%20extraction%20process%20-%20Chapter%201.pdf
http://umpir.ump.edu.my/id/eprint/22628/4/Extraction%20of%20bioactive%20compounds%20%28mangiferin%29%20from%20mahkota%20dewa%20fruits%20using%20subcritical%20water%20extraction%20process%20-%20References.pdf
http://umpir.ump.edu.my/id/eprint/22628/
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