Palladium(0) catalyzed Suzuki cross-coupling reaction of 2,5-dibromo-3-methylthiophene: selectivity, characterization, DFT studies and their biological evaluations

Thiophene derivatives have shown versatile pharmacological activities. The Suzuki reaction proved a convenient method for C–C bond formations in organic molecules. In the present research work novel derivatives of 2,5-dibromo-3-methylthiophene (3a–k and 3l–p) has been synthesized, via Suzuki couplin...

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Bibliographic Details
Main Authors: Rizwan, Komal, Zubair, Muhammad, Rasool, Nasir, Mahmood, Tariq, Ayub, Khurshid, Noorjahan Banu, Alitheen, Muhammad Nazirul Mubin, Aziz, Akhtar, Muhammad Nadeem, Nasim, Faiz-ul-Hassan, Bukhary, Snober Mona, Ahmad, Viqar Uddin, Rani, Mubeen
Format: Article
Language:English
Published: Springer Open 2018
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Online Access:http://umpir.ump.edu.my/id/eprint/22383/1/Palladium%280%29%20catalyzed%20Suzuki%20cross.pdf
http://umpir.ump.edu.my/id/eprint/22383/
https://doi.org/10.1186/s13065-018-0404-7
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