Metformin - A Panacea Pharmaceutical Agent through convergence revolution initiative

Metformin has been known to the mankind for centuries. Metformin is the first line of drug of choice for the treatment of type 2 diabetes. Initial pharmaceutical therapy was for treating the frequent urinal problem which is a primary manifestation of diabetes. At the time of writing, metformin as an...

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Main Authors: Prabhakaran, Sonia, Thirumal , Dhiviya, Jolius, Gimbun, Ranganathan, Balu
Format: Article
Language:English
Published: Informatics Publishing Limited 2017
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Online Access:http://umpir.ump.edu.my/id/eprint/20659/1/Metformin%20-%20A%20Panacea%20Pharmaceutical%20Agent%20through%20convergence-fkksa-2017.pdf
http://umpir.ump.edu.my/id/eprint/20659/
http://www.informaticsjournals.com/index.php/jnr/article/view/17938
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spelling my.ump.umpir.206592018-03-01T05:25:31Z http://umpir.ump.edu.my/id/eprint/20659/ Metformin - A Panacea Pharmaceutical Agent through convergence revolution initiative Prabhakaran, Sonia Thirumal , Dhiviya Jolius, Gimbun Ranganathan, Balu TP Chemical technology Metformin has been known to the mankind for centuries. Metformin is the first line of drug of choice for the treatment of type 2 diabetes. Initial pharmaceutical therapy was for treating the frequent urinal problem which is a primary manifestation of diabetes. At the time of writing, metformin as an intervention is looked into for cardiovascular risks, polycystic ovary syndrome and breast cancer. Annual demand for Metformin is 23,000 Metric tons per annum. Nano Drug Delivery Systems (NDDS) has embarked into Metformin controlled and targeted delivery for breast cancer, pancreatic cancer and non-small cell lung cancer. Clinical estimation of the biological fluids by the FDA approved diagnostic laboratories use LC-MS/MS where blood samples estimate Metformin as an intact molecule easing the pressure of clinical trials result. Metformin was manufactured by a less known and low profile Aoron pharmaceutical, France not aware of the block buster drug hence the potential of technology development start-ups can neither be underwritten nor underestimated even when there is a very high rate (~90%) of failed biotech/biomed start-up ventures. The bloom of the French lilac (metformin) to blossom and flower for the cure of breast cancer by convergence revolution initiative with the integration of academia, hospital, technology business incubator, multinational corporation with the deliverance of a start-up company Informatics Publishing Limited 2017 Article PeerReviewed application/pdf en cc_by http://umpir.ump.edu.my/id/eprint/20659/1/Metformin%20-%20A%20Panacea%20Pharmaceutical%20Agent%20through%20convergence-fkksa-2017.pdf Prabhakaran, Sonia and Thirumal , Dhiviya and Jolius, Gimbun and Ranganathan, Balu (2017) Metformin - A Panacea Pharmaceutical Agent through convergence revolution initiative. Journal of Natural Remedies, 17 (3). pp. 69-79. ISSN 2320-3358 http://www.informaticsjournals.com/index.php/jnr/article/view/17938
institution Universiti Malaysia Pahang
building UMP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang
content_source UMP Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
topic TP Chemical technology
spellingShingle TP Chemical technology
Prabhakaran, Sonia
Thirumal , Dhiviya
Jolius, Gimbun
Ranganathan, Balu
Metformin - A Panacea Pharmaceutical Agent through convergence revolution initiative
description Metformin has been known to the mankind for centuries. Metformin is the first line of drug of choice for the treatment of type 2 diabetes. Initial pharmaceutical therapy was for treating the frequent urinal problem which is a primary manifestation of diabetes. At the time of writing, metformin as an intervention is looked into for cardiovascular risks, polycystic ovary syndrome and breast cancer. Annual demand for Metformin is 23,000 Metric tons per annum. Nano Drug Delivery Systems (NDDS) has embarked into Metformin controlled and targeted delivery for breast cancer, pancreatic cancer and non-small cell lung cancer. Clinical estimation of the biological fluids by the FDA approved diagnostic laboratories use LC-MS/MS where blood samples estimate Metformin as an intact molecule easing the pressure of clinical trials result. Metformin was manufactured by a less known and low profile Aoron pharmaceutical, France not aware of the block buster drug hence the potential of technology development start-ups can neither be underwritten nor underestimated even when there is a very high rate (~90%) of failed biotech/biomed start-up ventures. The bloom of the French lilac (metformin) to blossom and flower for the cure of breast cancer by convergence revolution initiative with the integration of academia, hospital, technology business incubator, multinational corporation with the deliverance of a start-up company
format Article
author Prabhakaran, Sonia
Thirumal , Dhiviya
Jolius, Gimbun
Ranganathan, Balu
author_facet Prabhakaran, Sonia
Thirumal , Dhiviya
Jolius, Gimbun
Ranganathan, Balu
author_sort Prabhakaran, Sonia
title Metformin - A Panacea Pharmaceutical Agent through convergence revolution initiative
title_short Metformin - A Panacea Pharmaceutical Agent through convergence revolution initiative
title_full Metformin - A Panacea Pharmaceutical Agent through convergence revolution initiative
title_fullStr Metformin - A Panacea Pharmaceutical Agent through convergence revolution initiative
title_full_unstemmed Metformin - A Panacea Pharmaceutical Agent through convergence revolution initiative
title_sort metformin - a panacea pharmaceutical agent through convergence revolution initiative
publisher Informatics Publishing Limited
publishDate 2017
url http://umpir.ump.edu.my/id/eprint/20659/1/Metformin%20-%20A%20Panacea%20Pharmaceutical%20Agent%20through%20convergence-fkksa-2017.pdf
http://umpir.ump.edu.my/id/eprint/20659/
http://www.informaticsjournals.com/index.php/jnr/article/view/17938
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