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Bromelain: from Production to Commercialisation

Bromelain is a mixture of proteolytic enzymes found in pineapple (Ananas comosus) plants. It can be found in several parts of the pineapple plant, including the stem, fruit, leaves and peel. High demand for bromelain has resulted in gradual increases in bromelain production. These increases have led...

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Main Authors: Aizi Nor Mazila, Ramli, Tuan Norsyalieza, Tuan Aznan, Rosli, Md. Illias
Format: Article
Language:English
Published: Wiley 2016
Subjects:
S Agriculture (General)
Online Access:http://umpir.ump.edu.my/id/eprint/16737/2/JSFA8122%20%281%29.pdf
http://umpir.ump.edu.my/id/eprint/16737/
http://onlinelibrary.wiley.com/doi/10.1002/jsfa.8122/full
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spelling my.ump.umpir.167372018-07-26T01:55:20Z http://umpir.ump.edu.my/id/eprint/16737/ Bromelain: from Production to Commercialisation Aizi Nor Mazila, Ramli Tuan Norsyalieza, Tuan Aznan Rosli, Md. Illias S Agriculture (General) Bromelain is a mixture of proteolytic enzymes found in pineapple (Ananas comosus) plants. It can be found in several parts of the pineapple plant, including the stem, fruit, leaves and peel. High demand for bromelain has resulted in gradual increases in bromelain production. These increases have led to the need for a bromelain production strategy that yields more purified bromelain at a lower cost and with fewer production steps. Previously, bromelain was purified by conventional centrifugation, ultrafiltration and lyophilisation. Recently, the development of more modern purification techniques such as gel filtration, ion exchange chromatography, affinity chromatography, aqueous two-phase extraction and reverse micelle chromatography has resulted in increased industrial bromelain production worldwide. In addition, recombinant DNA technology has emerged as an alternative strategy for producing large amounts of ultrapure bromelain. An up-to-date compilation of data regarding the commercialisation of bromelain in the clinical, pharmaceutical and industrial fields is provided in this review. Wiley 2016-11 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/16737/2/JSFA8122%20%281%29.pdf Aizi Nor Mazila, Ramli and Tuan Norsyalieza, Tuan Aznan and Rosli, Md. Illias (2016) Bromelain: from Production to Commercialisation. Journal of the Science of Food and Agriculture. pp. 1-10. http://onlinelibrary.wiley.com/doi/10.1002/jsfa.8122/full DOI 10.1002/jsfa.8122
institution Universiti Malaysia Pahang
building UMP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang
content_source UMP Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
topic S Agriculture (General)
spellingShingle S Agriculture (General)
Aizi Nor Mazila, Ramli
Tuan Norsyalieza, Tuan Aznan
Rosli, Md. Illias
Bromelain: from Production to Commercialisation
description Bromelain is a mixture of proteolytic enzymes found in pineapple (Ananas comosus) plants. It can be found in several parts of the pineapple plant, including the stem, fruit, leaves and peel. High demand for bromelain has resulted in gradual increases in bromelain production. These increases have led to the need for a bromelain production strategy that yields more purified bromelain at a lower cost and with fewer production steps. Previously, bromelain was purified by conventional centrifugation, ultrafiltration and lyophilisation. Recently, the development of more modern purification techniques such as gel filtration, ion exchange chromatography, affinity chromatography, aqueous two-phase extraction and reverse micelle chromatography has resulted in increased industrial bromelain production worldwide. In addition, recombinant DNA technology has emerged as an alternative strategy for producing large amounts of ultrapure bromelain. An up-to-date compilation of data regarding the commercialisation of bromelain in the clinical, pharmaceutical and industrial fields is provided in this review.
format Article
author Aizi Nor Mazila, Ramli
Tuan Norsyalieza, Tuan Aznan
Rosli, Md. Illias
author_facet Aizi Nor Mazila, Ramli
Tuan Norsyalieza, Tuan Aznan
Rosli, Md. Illias
author_sort Aizi Nor Mazila, Ramli
title Bromelain: from Production to Commercialisation
title_short Bromelain: from Production to Commercialisation
title_full Bromelain: from Production to Commercialisation
title_fullStr Bromelain: from Production to Commercialisation
title_full_unstemmed Bromelain: from Production to Commercialisation
title_sort bromelain: from production to commercialisation
publisher Wiley
publishDate 2016
url http://umpir.ump.edu.my/id/eprint/16737/2/JSFA8122%20%281%29.pdf
http://umpir.ump.edu.my/id/eprint/16737/
http://onlinelibrary.wiley.com/doi/10.1002/jsfa.8122/full
_version_ 1643668005812436992
score 13.211869

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