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A New Neuron Ion Channel Model with Noisy Input Current

The data processing fundamental problem affects all aspects of nervous-system function by the noise of ion channels. The conducting and non conducting of ion channels depends on random transitions of channel noise, which affect the states of several numbers of gates in every single individual ion ch...

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Main Authors: Khudhur, Ahmed Mahmood, Abdalla, Ahmed N.
Format: Article
Language:English
Published: Penerbit Universiti Malaysia Pahang 2015
Subjects:
T Technology (General)
Online Access:http://umpir.ump.edu.my/id/eprint/10628/1/A%20New%20Neuron%20Ion%20Channel%20Model%20with%20Noisy%20Input%20Current.pdf
http://umpir.ump.edu.my/id/eprint/10628/
http://ijets.ump.edu.my/images/archive/Vol3-new/5.pdf
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spelling my.ump.umpir.106282018-10-03T07:32:51Z http://umpir.ump.edu.my/id/eprint/10628/ A New Neuron Ion Channel Model with Noisy Input Current Khudhur, Ahmed Mahmood Abdalla, Ahmed N. T Technology (General) The data processing fundamental problem affects all aspects of nervous-system function by the noise of ion channels. The conducting and non conducting of ion channels depends on random transitions of channel noise, which affect the states of several numbers of gates in every single individual ion channel. This paper, introduce a new ion channel model in the neuron with noisy input current as approximations of the HH model. It briefly introduces the ion channel based on stochastic Hodgkin-Huxley model. The method is able to fully constrain the HH model and obtain all models capable of reproducing the data. Therefore, this method overcomes the limitations of other parameter estimation methods. The stochastic Markov process method is simply applied to simulate each gate individually to determine the relationship between channel noise and the spike frequency. Penerbit Universiti Malaysia Pahang 2015 Article PeerReviewed application/pdf en cc_by http://umpir.ump.edu.my/id/eprint/10628/1/A%20New%20Neuron%20Ion%20Channel%20Model%20with%20Noisy%20Input%20Current.pdf Khudhur, Ahmed Mahmood and Abdalla, Ahmed N. (2015) A New Neuron Ion Channel Model with Noisy Input Current. International Journal of Engineering Technology And Sciences (IJETS), 3 (1). pp. 1-7. ISSN 2289-697X http://ijets.ump.edu.my/images/archive/Vol3-new/5.pdf DOI: 10.15282/ijets.3.2015.1.5.1022
institution Universiti Malaysia Pahang
building UMP Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Pahang
content_source UMP Institutional Repository
url_provider http://umpir.ump.edu.my/
language English
topic T Technology (General)
spellingShingle T Technology (General)
Khudhur, Ahmed Mahmood
Abdalla, Ahmed N.
A New Neuron Ion Channel Model with Noisy Input Current
description The data processing fundamental problem affects all aspects of nervous-system function by the noise of ion channels. The conducting and non conducting of ion channels depends on random transitions of channel noise, which affect the states of several numbers of gates in every single individual ion channel. This paper, introduce a new ion channel model in the neuron with noisy input current as approximations of the HH model. It briefly introduces the ion channel based on stochastic Hodgkin-Huxley model. The method is able to fully constrain the HH model and obtain all models capable of reproducing the data. Therefore, this method overcomes the limitations of other parameter estimation methods. The stochastic Markov process method is simply applied to simulate each gate individually to determine the relationship between channel noise and the spike frequency.
format Article
author Khudhur, Ahmed Mahmood
Abdalla, Ahmed N.
author_facet Khudhur, Ahmed Mahmood
Abdalla, Ahmed N.
author_sort Khudhur, Ahmed Mahmood
title A New Neuron Ion Channel Model with Noisy Input Current
title_short A New Neuron Ion Channel Model with Noisy Input Current
title_full A New Neuron Ion Channel Model with Noisy Input Current
title_fullStr A New Neuron Ion Channel Model with Noisy Input Current
title_full_unstemmed A New Neuron Ion Channel Model with Noisy Input Current
title_sort new neuron ion channel model with noisy input current
publisher Penerbit Universiti Malaysia Pahang
publishDate 2015
url http://umpir.ump.edu.my/id/eprint/10628/1/A%20New%20Neuron%20Ion%20Channel%20Model%20with%20Noisy%20Input%20Current.pdf
http://umpir.ump.edu.my/id/eprint/10628/
http://ijets.ump.edu.my/images/archive/Vol3-new/5.pdf
_version_ 1643666442502012928
score 13.211869

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