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A review: interactions of equine herpesvirus-1 with immune system and equine lymphocyte

Equine herpesvirus-1 (EHV-1) remains one of the most common viral pathogens affecting horses worldwide presenting as a persistent infection which can establish latency in nerve ganglia (trigeminal ganglion), lymphoid tissues of the respiratory tract and peripheral blood lymphocytes. EHV-1 infection...

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Main Authors: Nor Dini Rusli,, Khairiyah Binti Mat,, Hasnita Che Harun
Format: Non-Indexed Article
Published: 2014
Online Access:http://discol.umk.edu.my/id/eprint/8079/
http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52256
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spelling my.umk.eprints.80792022-05-23T10:25:10Z http://discol.umk.edu.my/id/eprint/8079/ A review: interactions of equine herpesvirus-1 with immune system and equine lymphocyte Nor Dini Rusli, Khairiyah Binti Mat, Hasnita Che Harun Equine herpesvirus-1 (EHV-1) remains one of the most common viral pathogens affecting horses worldwide presenting as a persistent infection which can establish latency in nerve ganglia (trigeminal ganglion), lymphoid tissues of the respiratory tract and peripheral blood lymphocytes. EHV-1 infection induces both humoral and cellular immune responses in horses. Virus neutralising antibody, particularly in the nasopharynx, is to kill free virus shed from infected epithelial cells. Hence this antibody has important functions in reducing virus shedding and spreading infection to cohorts. Cellular immune responses, particularly those carried out by cytotoxic T lymphocyte (CTL), have been shown to be effective in killing virus-infected cells in vitro. This review underlines the state of knowledge regarding immunity to EHV-1 and also its interaction with equine lymphocyte. Finally, the review also includes the importance of the viral immediate early (IE) protein in the pathogenesis of EHV-1. This information can be used as the basis for future research. 2014 Non-Indexed Article NonPeerReviewed Nor Dini Rusli, and Khairiyah Binti Mat, and Hasnita Che Harun (2014) A review: interactions of equine herpesvirus-1 with immune system and equine lymphocyte. Scientific Research, 4 (12). pp. 294-307. http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52256
institution Universiti Malaysia Kelantan
building Perpustakaan Universiti Malaysia Kelantan
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Kelantan
content_source UMK Institutional Repository
url_provider http://umkeprints.umk.edu.my/
description Equine herpesvirus-1 (EHV-1) remains one of the most common viral pathogens affecting horses worldwide presenting as a persistent infection which can establish latency in nerve ganglia (trigeminal ganglion), lymphoid tissues of the respiratory tract and peripheral blood lymphocytes. EHV-1 infection induces both humoral and cellular immune responses in horses. Virus neutralising antibody, particularly in the nasopharynx, is to kill free virus shed from infected epithelial cells. Hence this antibody has important functions in reducing virus shedding and spreading infection to cohorts. Cellular immune responses, particularly those carried out by cytotoxic T lymphocyte (CTL), have been shown to be effective in killing virus-infected cells in vitro. This review underlines the state of knowledge regarding immunity to EHV-1 and also its interaction with equine lymphocyte. Finally, the review also includes the importance of the viral immediate early (IE) protein in the pathogenesis of EHV-1. This information can be used as the basis for future research.
format Non-Indexed Article
author Nor Dini Rusli,
Khairiyah Binti Mat,
Hasnita Che Harun
spellingShingle Nor Dini Rusli,
Khairiyah Binti Mat,
Hasnita Che Harun
A review: interactions of equine herpesvirus-1 with immune system and equine lymphocyte
author_facet Nor Dini Rusli,
Khairiyah Binti Mat,
Hasnita Che Harun
author_sort Nor Dini Rusli,
title A review: interactions of equine herpesvirus-1 with immune system and equine lymphocyte
title_short A review: interactions of equine herpesvirus-1 with immune system and equine lymphocyte
title_full A review: interactions of equine herpesvirus-1 with immune system and equine lymphocyte
title_fullStr A review: interactions of equine herpesvirus-1 with immune system and equine lymphocyte
title_full_unstemmed A review: interactions of equine herpesvirus-1 with immune system and equine lymphocyte
title_sort review: interactions of equine herpesvirus-1 with immune system and equine lymphocyte
publishDate 2014
url http://discol.umk.edu.my/id/eprint/8079/
http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52256
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score 13.211869

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