Comparative efficacy between surgical intervention, organophosphorus and ivermectin against humpsore (Stephanofilariasis) in cattle

The experiment was carried out in 40 cattle to investigate the comparative efficacy of surgical intervention, using organophosphorus (Neguvon R ) and ivermectin against skin lesions due to Stephanofilariasis. Cattle of 1.5 to 6 years of age irrespective of sex having diagnosed skin lesions (Stephano...

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Main Authors: M.Z.U. Ibrahim, M.A. Hashim, M.A.Hossain, Imad Ibrahim Ali Al-Sultan
Format: Indexed Article
Published: Design for Scientific Renaissance 2013
Online Access:http://discol.umk.edu.my/id/eprint/7540/
http://www.sign-ific-ance.co.uk/index.php/JABPAR
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spelling my.umk.eprints.75402022-05-23T10:01:00Z http://discol.umk.edu.my/id/eprint/7540/ Comparative efficacy between surgical intervention, organophosphorus and ivermectin against humpsore (Stephanofilariasis) in cattle M.Z.U. Ibrahim M.A. Hashim M.A.Hossain Imad Ibrahim Ali Al-Sultan The experiment was carried out in 40 cattle to investigate the comparative efficacy of surgical intervention, using organophosphorus (Neguvon R ) and ivermectin against skin lesions due to Stephanofilariasis. Cattle of 1.5 to 6 years of age irrespective of sex having diagnosed skin lesions (Stephanofilariasis) were used in this experiment. Selected cattle were divided into four equal groups (group A, B, C and D): each group consisted of 10 cattle. Group A was treated by surgical excision of affected skin lesion. Animals of group B was treated with organophosphorus, Trichlorophon (Neguvon R Sapco, Unichem, Bangladesh) ointment applied topically. Group C treated with Ivermectin (A-mectin, The ACME Lab. Ltd, Bangladesh) was administered subcutaneously @ 0.2 mg/kg body weight and repeated after 21 days at same dose. Group D kept as control Group. Cattle treated surgically were completely cured within 15-20 days in all cases. The rate of healing of lesions was rapid compare to organophosphorus and ivermectin treated groups and success of healing was 100%, whereas animals treated with organophosphorus ointment cured partially after 45 days of treatment and success of healing was 60% and those treated with ivermectin also cured partially in 45 days of treatment and the success of healing was 70%. Surgical excision was more effective in comparison to other treatments in respect to time required for healing, presence of exudates, alopecia and recurrence of infection which was shown by histopathologically as the restoration of surrounding hair follicle and increased production of new capillaries around the scar tissue at the newly cured area. Also, it was evident that the treatment with ivermectin was more effective than organophosphorus application in success of healing. It is suggested that surgical excision of the lesions produced by Stephanofilariasis may be used as an alternative treatment method in cattle. Design for Scientific Renaissance 2013-11-01 Indexed Article NonPeerReviewed M.Z.U. Ibrahim and M.A. Hashim and M.A.Hossain and Imad Ibrahim Ali Al-Sultan (2013) Comparative efficacy between surgical intervention, organophosphorus and ivermectin against humpsore (Stephanofilariasis) in cattle. Journal of Advanced Biomedical & Pathobiology Research, 3 (3). pp. 100-109. ISSN 2231-9123 http://www.sign-ific-ance.co.uk/index.php/JABPAR
institution Universiti Malaysia Kelantan
building Perpustakaan Universiti Malaysia Kelantan
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Kelantan
content_source UMK Institutional Repository
url_provider http://umkeprints.umk.edu.my/
description The experiment was carried out in 40 cattle to investigate the comparative efficacy of surgical intervention, using organophosphorus (Neguvon R ) and ivermectin against skin lesions due to Stephanofilariasis. Cattle of 1.5 to 6 years of age irrespective of sex having diagnosed skin lesions (Stephanofilariasis) were used in this experiment. Selected cattle were divided into four equal groups (group A, B, C and D): each group consisted of 10 cattle. Group A was treated by surgical excision of affected skin lesion. Animals of group B was treated with organophosphorus, Trichlorophon (Neguvon R Sapco, Unichem, Bangladesh) ointment applied topically. Group C treated with Ivermectin (A-mectin, The ACME Lab. Ltd, Bangladesh) was administered subcutaneously @ 0.2 mg/kg body weight and repeated after 21 days at same dose. Group D kept as control Group. Cattle treated surgically were completely cured within 15-20 days in all cases. The rate of healing of lesions was rapid compare to organophosphorus and ivermectin treated groups and success of healing was 100%, whereas animals treated with organophosphorus ointment cured partially after 45 days of treatment and success of healing was 60% and those treated with ivermectin also cured partially in 45 days of treatment and the success of healing was 70%. Surgical excision was more effective in comparison to other treatments in respect to time required for healing, presence of exudates, alopecia and recurrence of infection which was shown by histopathologically as the restoration of surrounding hair follicle and increased production of new capillaries around the scar tissue at the newly cured area. Also, it was evident that the treatment with ivermectin was more effective than organophosphorus application in success of healing. It is suggested that surgical excision of the lesions produced by Stephanofilariasis may be used as an alternative treatment method in cattle.
format Indexed Article
author M.Z.U. Ibrahim
M.A. Hashim
M.A.Hossain
Imad Ibrahim Ali Al-Sultan
spellingShingle M.Z.U. Ibrahim
M.A. Hashim
M.A.Hossain
Imad Ibrahim Ali Al-Sultan
Comparative efficacy between surgical intervention, organophosphorus and ivermectin against humpsore (Stephanofilariasis) in cattle
author_facet M.Z.U. Ibrahim
M.A. Hashim
M.A.Hossain
Imad Ibrahim Ali Al-Sultan
author_sort M.Z.U. Ibrahim
title Comparative efficacy between surgical intervention, organophosphorus and ivermectin against humpsore (Stephanofilariasis) in cattle
title_short Comparative efficacy between surgical intervention, organophosphorus and ivermectin against humpsore (Stephanofilariasis) in cattle
title_full Comparative efficacy between surgical intervention, organophosphorus and ivermectin against humpsore (Stephanofilariasis) in cattle
title_fullStr Comparative efficacy between surgical intervention, organophosphorus and ivermectin against humpsore (Stephanofilariasis) in cattle
title_full_unstemmed Comparative efficacy between surgical intervention, organophosphorus and ivermectin against humpsore (Stephanofilariasis) in cattle
title_sort comparative efficacy between surgical intervention, organophosphorus and ivermectin against humpsore (stephanofilariasis) in cattle
publisher Design for Scientific Renaissance
publishDate 2013
url http://discol.umk.edu.my/id/eprint/7540/
http://www.sign-ific-ance.co.uk/index.php/JABPAR
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score 13.211869