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Toxicitty and chemical profiling of phyllanthus niruri, orthosiphon stamineus and andrographis paniculata

This study is to determine the toxicity of crude extract of medicinal plants, Phyllanthus niruri, Orthosiphon stamineus, Andrographis paniculata against Brine Shrimp i.e. BSLT Assay. The toxicity determined at certain concentrations of the medicinal plant at 0, 0.2, 2, 20, 200 against the percentag...

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Main Author: Muhammad Yusri Adib Samsudin
Format: Undergraduate Final Project Report
Published: 2013
Online Access:http://discol.umk.edu.my/id/eprint/5793/
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spelling my.umk.eprints.57932022-05-23T08:43:11Z http://discol.umk.edu.my/id/eprint/5793/ Toxicitty and chemical profiling of phyllanthus niruri, orthosiphon stamineus and andrographis paniculata Muhammad Yusri Adib Samsudin This study is to determine the toxicity of crude extract of medicinal plants, Phyllanthus niruri, Orthosiphon stamineus, Andrographis paniculata against Brine Shrimp i.e. BSLT Assay. The toxicity determined at certain concentrations of the medicinal plant at 0, 0.2, 2, 20, 200 against the percentage of mortality of brine shrimp. The result for of Hempedu Bumi (Andrographis paniculata) at concentrations 0, 0.2, 2, 20, 200 µg/ml were 0, 0, 30.00±0.4714, 76.67±0.4714, 96.67±0.4714. Dukung Anak (Phyllanthus niruri) at concentrations 0, 0.2, 2, 20, 200 μg/ml were 0, 3.33± 4.716, 30.00 ± 4.716, 76.66 ± 4.716, 93.33 and Misai Kucing (Orthosiphon stamineus) at concentration 0, 0.2, 2, 20, 200 μg/ml were 0, 0, 23.34 ± 4.716, 73.33, 93.33 respectively. The value of LC₅₀ for Hempedu Bumi (Andrographis paniculata), Dukung Anak (Phyllanthus niruri), and Misai Kucing (Orthosiphon stamineus) are 74.34 ± 0.5477, 68.38 ± 0.5477, and 69.82 ± 0.5477 respectively. The chemical profiling of the medicinal plant by using Thin Layer Chromatography give positive result because the compound increase to the upper layer of the TLC plate. It showed the compound have active component in all three medicinal plant. 2013 Undergraduate Final Project Report NonPeerReviewed Muhammad Yusri Adib Samsudin (2013) Toxicitty and chemical profiling of phyllanthus niruri, orthosiphon stamineus and andrographis paniculata. Undergraduate Final Project Report thesis, Faculty of Agro - Based Industry. (Submitted)
institution Universiti Malaysia Kelantan
building Perpustakaan Universiti Malaysia Kelantan
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Kelantan
content_source UMK Institutional Repository
url_provider http://umkeprints.umk.edu.my/
description This study is to determine the toxicity of crude extract of medicinal plants, Phyllanthus niruri, Orthosiphon stamineus, Andrographis paniculata against Brine Shrimp i.e. BSLT Assay. The toxicity determined at certain concentrations of the medicinal plant at 0, 0.2, 2, 20, 200 against the percentage of mortality of brine shrimp. The result for of Hempedu Bumi (Andrographis paniculata) at concentrations 0, 0.2, 2, 20, 200 µg/ml were 0, 0, 30.00±0.4714, 76.67±0.4714, 96.67±0.4714. Dukung Anak (Phyllanthus niruri) at concentrations 0, 0.2, 2, 20, 200 μg/ml were 0, 3.33± 4.716, 30.00 ± 4.716, 76.66 ± 4.716, 93.33 and Misai Kucing (Orthosiphon stamineus) at concentration 0, 0.2, 2, 20, 200 μg/ml were 0, 0, 23.34 ± 4.716, 73.33, 93.33 respectively. The value of LC₅₀ for Hempedu Bumi (Andrographis paniculata), Dukung Anak (Phyllanthus niruri), and Misai Kucing (Orthosiphon stamineus) are 74.34 ± 0.5477, 68.38 ± 0.5477, and 69.82 ± 0.5477 respectively. The chemical profiling of the medicinal plant by using Thin Layer Chromatography give positive result because the compound increase to the upper layer of the TLC plate. It showed the compound have active component in all three medicinal plant.
format Undergraduate Final Project Report
author Muhammad Yusri Adib Samsudin
spellingShingle Muhammad Yusri Adib Samsudin
Toxicitty and chemical profiling of phyllanthus niruri, orthosiphon stamineus and andrographis paniculata
author_facet Muhammad Yusri Adib Samsudin
author_sort Muhammad Yusri Adib Samsudin
title Toxicitty and chemical profiling of phyllanthus niruri, orthosiphon stamineus and andrographis paniculata
title_short Toxicitty and chemical profiling of phyllanthus niruri, orthosiphon stamineus and andrographis paniculata
title_full Toxicitty and chemical profiling of phyllanthus niruri, orthosiphon stamineus and andrographis paniculata
title_fullStr Toxicitty and chemical profiling of phyllanthus niruri, orthosiphon stamineus and andrographis paniculata
title_full_unstemmed Toxicitty and chemical profiling of phyllanthus niruri, orthosiphon stamineus and andrographis paniculata
title_sort toxicitty and chemical profiling of phyllanthus niruri, orthosiphon stamineus and andrographis paniculata
publishDate 2013
url http://discol.umk.edu.my/id/eprint/5793/
_version_ 1763303603984924672
score 13.211869

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