Cover Image

Preliminary study of phyllanthus niruri as a natural contraceptive for animals

An abstract of the research paper presented to the Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, in partial requirement on the course DVT 55204 - Research Project. Ongoing increases in the population of stray animals contributes to significant socioeconomic costs, environmental damag...

Full description

Saved in:
Bibliographic Details
Main Author: Amin Mustaqim Mohamad Fauzi
Format: Undergraduate Final Project Report
Language:English
Published: 2023
Online Access:http://discol.umk.edu.my/id/eprint/12924/1/D18A0029%20AMIN%20MUSTAQIM%20BIN%20MOHAMAD%20FAUZI.pdf
http://discol.umk.edu.my/id/eprint/12924/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.umk.eprints.12924
record_format eprints
spelling my.umk.eprints.129242023-04-11T07:34:00Z http://discol.umk.edu.my/id/eprint/12924/ Preliminary study of phyllanthus niruri as a natural contraceptive for animals Amin Mustaqim Mohamad Fauzi An abstract of the research paper presented to the Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, in partial requirement on the course DVT 55204 - Research Project. Ongoing increases in the population of stray animals contributes to significant socioeconomic costs, environmental damage and zoonotic disease burden worldwide. The most common stray animals in Malaysia are domesticated pet animals such as cats and dogs, with current population control measures determined to be largely inadequate in controlling population growth. This is a preliminary research study to investigate the potential contraceptive properties of the common indigenous Malaysian Stonebreaker plant, Phyllanthus niruri and determine its feasibility as an alternative population control method for stray animals. Therefore, crude extracts of P. niruri were prepared and tested for cytotoxicity via MTT and DNA apoptosis assays on feline testicular cells. Results suggest that P. niruri extracts possess antifertility properties in-vitro. In contrast, P. niruri extracts are relatively non-toxic with little to no evidence of DNA fragmentation occurring at doses several magnitudes higher than predicted clinical usage doses. Further study is recommended to explore the potential of P. niruri in both animal models and real-world conditions. Keywords: Phyllantus niruri, Feline Testicular Cells, Cytotoxicity, MTT assay, DNA apoptosis assay 2023-01 Undergraduate Final Project Report NonPeerReviewed text en http://discol.umk.edu.my/id/eprint/12924/1/D18A0029%20AMIN%20MUSTAQIM%20BIN%20MOHAMAD%20FAUZI.pdf Amin Mustaqim Mohamad Fauzi (2023) Preliminary study of phyllanthus niruri as a natural contraceptive for animals. Final Year Project thesis, Universiti Malaysia Kelantan. (Submitted)
institution Universiti Malaysia Kelantan
building Perpustakaan Universiti Malaysia Kelantan
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Kelantan
content_source UMK Institutional Repository
url_provider http://umkeprints.umk.edu.my/
language English
description An abstract of the research paper presented to the Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, in partial requirement on the course DVT 55204 - Research Project. Ongoing increases in the population of stray animals contributes to significant socioeconomic costs, environmental damage and zoonotic disease burden worldwide. The most common stray animals in Malaysia are domesticated pet animals such as cats and dogs, with current population control measures determined to be largely inadequate in controlling population growth. This is a preliminary research study to investigate the potential contraceptive properties of the common indigenous Malaysian Stonebreaker plant, Phyllanthus niruri and determine its feasibility as an alternative population control method for stray animals. Therefore, crude extracts of P. niruri were prepared and tested for cytotoxicity via MTT and DNA apoptosis assays on feline testicular cells. Results suggest that P. niruri extracts possess antifertility properties in-vitro. In contrast, P. niruri extracts are relatively non-toxic with little to no evidence of DNA fragmentation occurring at doses several magnitudes higher than predicted clinical usage doses. Further study is recommended to explore the potential of P. niruri in both animal models and real-world conditions. Keywords: Phyllantus niruri, Feline Testicular Cells, Cytotoxicity, MTT assay, DNA apoptosis assay
format Undergraduate Final Project Report
author Amin Mustaqim Mohamad Fauzi
spellingShingle Amin Mustaqim Mohamad Fauzi
Preliminary study of phyllanthus niruri as a natural contraceptive for animals
author_facet Amin Mustaqim Mohamad Fauzi
author_sort Amin Mustaqim Mohamad Fauzi
title Preliminary study of phyllanthus niruri as a natural contraceptive for animals
title_short Preliminary study of phyllanthus niruri as a natural contraceptive for animals
title_full Preliminary study of phyllanthus niruri as a natural contraceptive for animals
title_fullStr Preliminary study of phyllanthus niruri as a natural contraceptive for animals
title_full_unstemmed Preliminary study of phyllanthus niruri as a natural contraceptive for animals
title_sort preliminary study of phyllanthus niruri as a natural contraceptive for animals
publishDate 2023
url http://discol.umk.edu.my/id/eprint/12924/1/D18A0029%20AMIN%20MUSTAQIM%20BIN%20MOHAMAD%20FAUZI.pdf
http://discol.umk.edu.my/id/eprint/12924/
_version_ 1763304407862083584
score 13.211869

Similar Items