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Graphene oxide antifungal activities against aspergillus versicolor

An abstract of the research paper presented to the Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, in partial requirement on the course DVT 55204 – Research Project. Aspergillosis is a common fungal disease in animals and humans. The existing treatment of conventional antifungal may ha...

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Main Author: Ashyer Andderias
Format: Undergraduate Final Project Report
Language:English
Published: 2022
Online Access:http://discol.umk.edu.my/id/eprint/12909/1/D18A0004%20ASHYER%20ANDDERIAS.pdf
http://discol.umk.edu.my/id/eprint/12909/
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spelling my.umk.eprints.129092023-04-11T05:06:40Z http://discol.umk.edu.my/id/eprint/12909/ Graphene oxide antifungal activities against aspergillus versicolor Ashyer Andderias An abstract of the research paper presented to the Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, in partial requirement on the course DVT 55204 – Research Project. Aspergillosis is a common fungal disease in animals and humans. The existing treatment of conventional antifungal may have disadvantages as it can cause liver damage, severe allergic and increasing resistance towards the compound makes it partially effective. Therefore, it is important to find an alternative therapy for the problem. Recently, the application of carbonbased nanoparticles such as graphene oxide (GO) has received attention for biomedical application. GO has been tested for its antibacterial properties and showed some promising outcomes. However, it is unknown if the GO can also demonstrate antifungal properties. In this research, we aimed to determine GO fungicidal activity against Aspergillus versicolor and the toxicity in mammalian cells. Based on the results, GO have fungicidal activity against Aspergillus versicolor as we can observe inhibition zone of GO on the agar plate streaked with Aspergillus versicolor. Also, GO is less toxic towards mammalian cells as it can induce cell proliferation of Mardin-Darby Canine Kidney (MDCK) cells. Keywords: Graphene Oxide, Mardin-Darby Kidney cells, fungicidal activity, antifungal, toxicity cell growth, Aspergillosis 2022 Undergraduate Final Project Report NonPeerReviewed text en http://discol.umk.edu.my/id/eprint/12909/1/D18A0004%20ASHYER%20ANDDERIAS.pdf Ashyer Andderias (2022) Graphene oxide antifungal activities against aspergillus versicolor. Final Year Project thesis, Universiti Malaysia Kelantan. (Submitted)
institution Universiti Malaysia Kelantan
building Perpustakaan Universiti Malaysia Kelantan
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Kelantan
content_source UMK Institutional Repository
url_provider http://umkeprints.umk.edu.my/
language English
description An abstract of the research paper presented to the Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, in partial requirement on the course DVT 55204 – Research Project. Aspergillosis is a common fungal disease in animals and humans. The existing treatment of conventional antifungal may have disadvantages as it can cause liver damage, severe allergic and increasing resistance towards the compound makes it partially effective. Therefore, it is important to find an alternative therapy for the problem. Recently, the application of carbonbased nanoparticles such as graphene oxide (GO) has received attention for biomedical application. GO has been tested for its antibacterial properties and showed some promising outcomes. However, it is unknown if the GO can also demonstrate antifungal properties. In this research, we aimed to determine GO fungicidal activity against Aspergillus versicolor and the toxicity in mammalian cells. Based on the results, GO have fungicidal activity against Aspergillus versicolor as we can observe inhibition zone of GO on the agar plate streaked with Aspergillus versicolor. Also, GO is less toxic towards mammalian cells as it can induce cell proliferation of Mardin-Darby Canine Kidney (MDCK) cells. Keywords: Graphene Oxide, Mardin-Darby Kidney cells, fungicidal activity, antifungal, toxicity cell growth, Aspergillosis
format Undergraduate Final Project Report
author Ashyer Andderias
spellingShingle Ashyer Andderias
Graphene oxide antifungal activities against aspergillus versicolor
author_facet Ashyer Andderias
author_sort Ashyer Andderias
title Graphene oxide antifungal activities against aspergillus versicolor
title_short Graphene oxide antifungal activities against aspergillus versicolor
title_full Graphene oxide antifungal activities against aspergillus versicolor
title_fullStr Graphene oxide antifungal activities against aspergillus versicolor
title_full_unstemmed Graphene oxide antifungal activities against aspergillus versicolor
title_sort graphene oxide antifungal activities against aspergillus versicolor
publishDate 2022
url http://discol.umk.edu.my/id/eprint/12909/1/D18A0004%20ASHYER%20ANDDERIAS.pdf
http://discol.umk.edu.my/id/eprint/12909/
_version_ 1763304405724037120
score 13.211869

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