Prevalence of clostridium difficile infection in Hospital Sungai Buloh and the associated risk factors / Nurul Suhaiza Hassanudin

Clostridium difficile infection (CDI) is the major recognized cause of nosocomial diarrhoea. It causes mild to severe diarrhoea and also pseudomembranous colitis. One of the most important risk factors for CDI is prior antibiotic exposure.Data on CDI among malaysian patients are still very limited....

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Main Author: Nurul Suhaiza, Hassanudin
Format: Thesis
Published: 2017
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Online Access:http://studentsrepo.um.edu.my/8947/4/suhaiza.pdf
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spelling my.um.stud.89472019-08-27T00:02:54Z Prevalence of clostridium difficile infection in Hospital Sungai Buloh and the associated risk factors / Nurul Suhaiza Hassanudin Nurul Suhaiza, Hassanudin R Medicine (General) Clostridium difficile infection (CDI) is the major recognized cause of nosocomial diarrhoea. It causes mild to severe diarrhoea and also pseudomembranous colitis. One of the most important risk factors for CDI is prior antibiotic exposure.Data on CDI among malaysian patients are still very limited. We aim look at the prevalence of CDI among inpatients of Hospital ungai Buloh. This study involved data collection of the stool specimens from 198 patients suspected to have CDI. The presence of Toxin A and Toxin B was tested by a commercial immunochromatographic rapid test kit (Duo Toxin A+B Check- 1 by VEDALAB-France), followed by culture for C. difficile. Secondary data were collected from the patients' medical records to determine demographic data, clinical presentations and associated risk factors. The prevalence of CDI among our patients was 6.1 %, and majority of the patients were male. The most common presentations, apart from diarrhoea, were fever, abdominal pain and nausea. Leucocytosis, dehydration and electrolyte imbalances were the common signs. The median length of stay was 16 day. The most common preceding antibiotic was amoxycillin. All of our patients were nursed in double or more occupancy room. Eight (66.7%) had history of admission to long-term healthcare facilities within the past 1 year and l 0 (83.3%) of the CDT patient were hypoalbuminaemic. In conclusion, the prevalence of CDI in Hospital Sungai Buloh is relatively low. 2017 Thesis NonPeerReviewed application/pdf http://studentsrepo.um.edu.my/8947/4/suhaiza.pdf Nurul Suhaiza, Hassanudin (2017) Prevalence of clostridium difficile infection in Hospital Sungai Buloh and the associated risk factors / Nurul Suhaiza Hassanudin. Masters thesis, University of Malaya. http://studentsrepo.um.edu.my/8947/
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Student Repository
url_provider http://studentsrepo.um.edu.my/
topic R Medicine (General)
spellingShingle R Medicine (General)
Nurul Suhaiza, Hassanudin
Prevalence of clostridium difficile infection in Hospital Sungai Buloh and the associated risk factors / Nurul Suhaiza Hassanudin
description Clostridium difficile infection (CDI) is the major recognized cause of nosocomial diarrhoea. It causes mild to severe diarrhoea and also pseudomembranous colitis. One of the most important risk factors for CDI is prior antibiotic exposure.Data on CDI among malaysian patients are still very limited. We aim look at the prevalence of CDI among inpatients of Hospital ungai Buloh. This study involved data collection of the stool specimens from 198 patients suspected to have CDI. The presence of Toxin A and Toxin B was tested by a commercial immunochromatographic rapid test kit (Duo Toxin A+B Check- 1 by VEDALAB-France), followed by culture for C. difficile. Secondary data were collected from the patients' medical records to determine demographic data, clinical presentations and associated risk factors. The prevalence of CDI among our patients was 6.1 %, and majority of the patients were male. The most common presentations, apart from diarrhoea, were fever, abdominal pain and nausea. Leucocytosis, dehydration and electrolyte imbalances were the common signs. The median length of stay was 16 day. The most common preceding antibiotic was amoxycillin. All of our patients were nursed in double or more occupancy room. Eight (66.7%) had history of admission to long-term healthcare facilities within the past 1 year and l 0 (83.3%) of the CDT patient were hypoalbuminaemic. In conclusion, the prevalence of CDI in Hospital Sungai Buloh is relatively low.
format Thesis
author Nurul Suhaiza, Hassanudin
author_facet Nurul Suhaiza, Hassanudin
author_sort Nurul Suhaiza, Hassanudin
title Prevalence of clostridium difficile infection in Hospital Sungai Buloh and the associated risk factors / Nurul Suhaiza Hassanudin
title_short Prevalence of clostridium difficile infection in Hospital Sungai Buloh and the associated risk factors / Nurul Suhaiza Hassanudin
title_full Prevalence of clostridium difficile infection in Hospital Sungai Buloh and the associated risk factors / Nurul Suhaiza Hassanudin
title_fullStr Prevalence of clostridium difficile infection in Hospital Sungai Buloh and the associated risk factors / Nurul Suhaiza Hassanudin
title_full_unstemmed Prevalence of clostridium difficile infection in Hospital Sungai Buloh and the associated risk factors / Nurul Suhaiza Hassanudin
title_sort prevalence of clostridium difficile infection in hospital sungai buloh and the associated risk factors / nurul suhaiza hassanudin
publishDate 2017
url http://studentsrepo.um.edu.my/8947/4/suhaiza.pdf
http://studentsrepo.um.edu.my/8947/
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