Establishing the minimally important clinical difference for the oral health impact profile in Malaysians provided with removable partial dentures / Siti Fauzza Ahmad
Future demand for a removable partial denture (RPD) remains as more adults retain their natural teeth into old age. Partial tooth loss often leads to masticatory function disturbances and negatively affects the quality of life (QoL). Prosthodontic rehabilitation with RPD improves QoL; however,...
Saved in:
| Main Author: | |
|---|---|
| Format: | Thesis |
| Published: |
2021
|
| Subjects: | |
| Online Access: | http://studentsrepo.um.edu.my/12857/4/fauzza.pdf http://studentsrepo.um.edu.my/12857/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Future demand for a removable partial denture (RPD) remains as more adults retain their
natural teeth into old age. Partial tooth loss often leads to masticatory function
disturbances and negatively affects the quality of life (QoL). Prosthodontic rehabilitation
with RPD improves QoL; however, the statistically significant change with many Oral
Health-Related Quality of Life (OHRQOL) instruments, may not be clinically
meaningful. The Malaysian version of Oral Health Impact Profile, OHIP(M)-45
questionnaires has been validated and adapted; however, its clinical interpretability has
not been established. The smallest change in OHRQoL score perceived by a patient as
beneficial, following an intervention, is termed Minimal Important Difference (MID).
There are two methods to estimate the MID estimation; i) distribution-based approach
which compares changes in OHRQoL scores after intervention through statistical
parameters, ii) anchor-based approach which correlates the change with clinical
measures. This pre-post intervention study investigated the change in OHRQoL, partially
dentate subjects after RPD therapy and determined the MID for OHIP(M)45, using both
approaches. The association between subjective perception and clinical outcomes (bite
force and masticatory performance) were also determined. Subjects completed
OHIP(M)-45 questionnaires before and after the intervention. The OHIP(M)-45 score
ranges from 0-180 with a lower score indicating better OHRQoL. The clinical anchors,
Global Transitional Scale (GTS) questionnaire, bite force and masticatory performance
were used. Bite force was measured using a digital dynamometer while masticatory
performance using gravimetric sieving method, (mesh sizes ranging from 4.00mm to
0.425mm) with alginate pellet as a test food. Statistical analysis was performed using
iv
Paired t-test, Wilcoxon Signed Rank and Friedmann test for within and between
comparison while the relationship between subjective and objective measurements using
Linear Regression and Spearman Rho. A total of 118 subjects enrolled with mean age
58.3 (SD±10.4) years, number of teeth 16.0 (SD±6.6) and number of occluding pairs 4.8
(SD±3.8). A significant reduction of 40% in the prevalence of impact (p<0.001) was
observed with RPD therapy. The mean OHIP(M)-45 change score was 17.36 (95%CI
(13.53;21.20, ES=0.76, p<0.001) with high treatment effect in the domains of physical
pain (ES=0.78) and psychological discomfort (0.82) and low effect in social disability
domain (ES=0.30). The GTS measure showed that 13%-24% of subjects perceived a little
improvement in their QoL, mainly in chewing with a significant association (p<0.05).
The estimated MID was 11. A significant increase in bite force (p<0.05) and
improvement in masticatory performance (p<0.05) with the new dentures were observed,
and a significant association was found between them. However, they showed no
significant association with the change in OHIP(M)-45 scores. MID estimates using bite
force and masticatory performance as anchors were 19 and 21 OHIP units respectively.
In conclusion, RPD therapy improved subjects' OHRQoL, bite force and masticatory
performance. The OHIP(M)-45 instrument is found to be responsive and sensitive to
change, and the MID for OHIP(M)-45 for RPD therapy is established.
Keywords: OHRQoL, MID, removable partial denture, bite force, masticatory
performance |
|---|