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Immobilization of bovine serum albumin on chitosan/PVA film: Physical and mechanical properties investigation / Nurul Mujahidah Ahmad Khairuddin

Chitosan/ polyvinyl alcohol (Ch/PVA) blended film was prepared by direct blend process and solution casting methods. In order to reduce the swelling ratio and enhance the chemical and mechanical stability, Ch/PVA film was crosslinked with glutaraldehyde in order to produce Ch-g-PVA. Bovine serum alb...

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Main Author: Nurul Mujahidah , Ahmad Khairuddin
Format: Thesis
Published: 2019
Subjects:
TJ Mechanical engineering and machinery
Online Access:http://studentsrepo.um.edu.my/10603/1/Nurul_Mujahidah_Ahmad_Khairuddin.jpg
http://studentsrepo.um.edu.my/10603/7/nurul.pdf
http://studentsrepo.um.edu.my/10603/
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spelling my.um.stud.106032020-01-18T01:56:55Z Immobilization of bovine serum albumin on chitosan/PVA film: Physical and mechanical properties investigation / Nurul Mujahidah Ahmad Khairuddin Nurul Mujahidah , Ahmad Khairuddin TJ Mechanical engineering and machinery Chitosan/ polyvinyl alcohol (Ch/PVA) blended film was prepared by direct blend process and solution casting methods. In order to reduce the swelling ratio and enhance the chemical and mechanical stability, Ch/PVA film was crosslinked with glutaraldehyde in order to produce Ch-g-PVA. Bovine serum albumin (BSA) was used as a model protein to incorporate into the Ch-g-PVA. The chemical structure and morphological characteristics of films were studied by FT-IR and Field-emission scanning electron microscopy (FESEM). Mechanical and physical properties of blended films such as tensile properties in the dry and wet states, water uptake, and water contact angle measurement were characterized. Blending PVA and chitosan improved strength and flexibility of the films. Crosslinking with glutaraldehyde further improves the tensile strength and decrease the hydrophilicity of films. BSA immobilized on the Ch-g-PVA film was calculated as BSA encapsulation efficiency. All results indicated that chemical modification with glutaraldehyde and BSA turns films more hydrophobic 2019-05 Thesis NonPeerReviewed image/jpeg http://studentsrepo.um.edu.my/10603/1/Nurul_Mujahidah_Ahmad_Khairuddin.jpg application/pdf http://studentsrepo.um.edu.my/10603/7/nurul.pdf Nurul Mujahidah , Ahmad Khairuddin (2019) Immobilization of bovine serum albumin on chitosan/PVA film: Physical and mechanical properties investigation / Nurul Mujahidah Ahmad Khairuddin. Masters thesis, University of Malaya. http://studentsrepo.um.edu.my/10603/
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Student Repository
url_provider http://studentsrepo.um.edu.my/
topic TJ Mechanical engineering and machinery
spellingShingle TJ Mechanical engineering and machinery
Nurul Mujahidah , Ahmad Khairuddin
Immobilization of bovine serum albumin on chitosan/PVA film: Physical and mechanical properties investigation / Nurul Mujahidah Ahmad Khairuddin
description Chitosan/ polyvinyl alcohol (Ch/PVA) blended film was prepared by direct blend process and solution casting methods. In order to reduce the swelling ratio and enhance the chemical and mechanical stability, Ch/PVA film was crosslinked with glutaraldehyde in order to produce Ch-g-PVA. Bovine serum albumin (BSA) was used as a model protein to incorporate into the Ch-g-PVA. The chemical structure and morphological characteristics of films were studied by FT-IR and Field-emission scanning electron microscopy (FESEM). Mechanical and physical properties of blended films such as tensile properties in the dry and wet states, water uptake, and water contact angle measurement were characterized. Blending PVA and chitosan improved strength and flexibility of the films. Crosslinking with glutaraldehyde further improves the tensile strength and decrease the hydrophilicity of films. BSA immobilized on the Ch-g-PVA film was calculated as BSA encapsulation efficiency. All results indicated that chemical modification with glutaraldehyde and BSA turns films more hydrophobic
format Thesis
author Nurul Mujahidah , Ahmad Khairuddin
author_facet Nurul Mujahidah , Ahmad Khairuddin
author_sort Nurul Mujahidah , Ahmad Khairuddin
title Immobilization of bovine serum albumin on chitosan/PVA film: Physical and mechanical properties investigation / Nurul Mujahidah Ahmad Khairuddin
title_short Immobilization of bovine serum albumin on chitosan/PVA film: Physical and mechanical properties investigation / Nurul Mujahidah Ahmad Khairuddin
title_full Immobilization of bovine serum albumin on chitosan/PVA film: Physical and mechanical properties investigation / Nurul Mujahidah Ahmad Khairuddin
title_fullStr Immobilization of bovine serum albumin on chitosan/PVA film: Physical and mechanical properties investigation / Nurul Mujahidah Ahmad Khairuddin
title_full_unstemmed Immobilization of bovine serum albumin on chitosan/PVA film: Physical and mechanical properties investigation / Nurul Mujahidah Ahmad Khairuddin
title_sort immobilization of bovine serum albumin on chitosan/pva film: physical and mechanical properties investigation / nurul mujahidah ahmad khairuddin
publishDate 2019
url http://studentsrepo.um.edu.my/10603/1/Nurul_Mujahidah_Ahmad_Khairuddin.jpg
http://studentsrepo.um.edu.my/10603/7/nurul.pdf
http://studentsrepo.um.edu.my/10603/
_version_ 1738506387992870912
score 13.211869

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