Myeloma-induced alloreactive T cells arising in Myeloma-infiltrated bones include double-positive CD8(+)CD4(+) T cells: evidence from myeloma-bearing mouse model

The graft-versus-myeloma (GVM) effect represents a powerful form of immune attack exerted by alloreactive T cells against multiple myeloma cells, which leads to clinical responses in multiple myeloma transplant recipients. Whether myeloma cells are themselves able to induce alloreactive T cells capa...

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Main Authors: Freeman, L.M., Lam, A., Petcu, E., Smith, R., Salajegheh, A., Diamond, P., Zannettino, A., Evdokiou, A., Luff, J., Wong, P.F., Khalil, D., Waterhouse, N., Vari, F., Rice, A.M., Catley, L., Hart, D.N.J., Vuckovic, S.
Format: Article
Language:English
Published: 2011
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Online Access:http://eprints.um.edu.my/8534/1/Myeloma-induced_alloreactive_t-cells.pdf
http://eprints.um.edu.my/8534/
http://www.jimmunol.org/content/187/8/3987.full.pdf
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