Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol
Calcitriol (1,25-dihydroxycholecalciferol), the most active form of vitamin D, has selective anti-proliferative effects on tumor-derived endothelial cells (TDEC) compared with Matrigel-derived endothelial cells (MDEC). Although both cell types have an intact vitamin D receptor-signaling axis, this s...
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Main Authors: | Chung, I., Karpf, A.R., Muindi, J.R., Conroy, J.M., Nowak, N.J., Johnson, C.S., Trump, D.L. |
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Format: | Article |
Language: | English |
Published: |
2007
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Subjects: | |
Online Access: | http://eprints.um.edu.my/5079/1/Chung-2007-Epigenetic_silencing.pdf http://eprints.um.edu.my/5079/ |
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