Staff View: Evolution of Iron-Based Metallic Glass Composite Coating with Enhanced Corrosion Resistance and Biocompatibility

Evolution of Iron-Based Metallic Glass Composite Coating with Enhanced Corrosion Resistance and Biocompatibility

Metallic glasses are a new class of metallic alloys that attract increasing attention in bone implants due to their ultrahigh wear resistance and hardness, high toughness and superior strength. However, their cytotoxicity and biocorrosion resistance are still under investigation. In this research, t...

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Main Authors:	Ibrahim, Mahmoud Z., Sarhan, A. A. D., Kuo, T. Y., Yusof, Farazila, Hamdi, M., Chang, C. P., Lee, T. M., Chien, C. S.
Format:	Article
Published:	Springer 2024
Subjects:	TJ Mechanical engineering and machinery
Online Access:	http://eprints.um.edu.my/47149/ https://doi.org/10.1007/s13369-023-08406-3
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spelling	my.um.eprints.471492024-12-31T06:59:06Z http://eprints.um.edu.my/47149/ Evolution of Iron-Based Metallic Glass Composite Coating with Enhanced Corrosion Resistance and Biocompatibility Ibrahim, Mahmoud Z. Sarhan, A. A. D. Kuo, T. Y. Yusof, Farazila Hamdi, M. Chang, C. P. Lee, T. M. Chien, C. S. TJ Mechanical engineering and machinery Metallic glasses are a new class of metallic alloys that attract increasing attention in bone implants due to their ultrahigh wear resistance and hardness, high toughness and superior strength. However, their cytotoxicity and biocorrosion resistance are still under investigation. In this research, the cytotoxicity and biocorrosion resistance of iron-based metallic glass composite coating are explored. To approach real-life conditions, the biocorrosion resistance of the proposed coating in phosphate buffer saline (PBS) is evaluated via immersion test for 30 days followed by an electrochemical corrosion test. Then, human bone cells (MG-63) are cultured on corroded samples and the cell viability is determined using MTT assay, in addition to cell attachment examination. The results revealed the formation of a metallic glass composite layer with 78.76% amorphous content. Additionally, the metallic glass composite demonstrated excellent and stable corrosion resistance in PBS over 30 days compared to the substrate. The MTT assay has shown that the cytotoxicity of iron-based metallic glass composite is within the permitted levels according to ISO 10993-5, Part 5 vol 2009. The cells were well attached to the surface besides, showing a healthy growth after 7 days of culture. These results confirm the in vitro biocompatibility of iron-based metallic glass composite coating for biomedical implant applications. Springer 2024-08 Article PeerReviewed Ibrahim, Mahmoud Z. and Sarhan, A. A. D. and Kuo, T. Y. and Yusof, Farazila and Hamdi, M. and Chang, C. P. and Lee, T. M. and Chien, C. S. (2024) Evolution of Iron-Based Metallic Glass Composite Coating with Enhanced Corrosion Resistance and Biocompatibility. Arabian Journal for Science and Engineering, 49 (8). pp. 10547-10559. ISSN 2193-567X, DOI https://doi.org/10.1007/s13369-023-08406-3 <https://doi.org/10.1007/s13369-023-08406-3>. https://doi.org/10.1007/s13369-023-08406-3 10.1007/s13369-023-08406-3
institution	Universiti Malaya
building	UM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaya
content_source	UM Research Repository
url_provider	http://eprints.um.edu.my/
topic	TJ Mechanical engineering and machinery
spellingShingle	TJ Mechanical engineering and machinery Ibrahim, Mahmoud Z. Sarhan, A. A. D. Kuo, T. Y. Yusof, Farazila Hamdi, M. Chang, C. P. Lee, T. M. Chien, C. S. Evolution of Iron-Based Metallic Glass Composite Coating with Enhanced Corrosion Resistance and Biocompatibility
description	Metallic glasses are a new class of metallic alloys that attract increasing attention in bone implants due to their ultrahigh wear resistance and hardness, high toughness and superior strength. However, their cytotoxicity and biocorrosion resistance are still under investigation. In this research, the cytotoxicity and biocorrosion resistance of iron-based metallic glass composite coating are explored. To approach real-life conditions, the biocorrosion resistance of the proposed coating in phosphate buffer saline (PBS) is evaluated via immersion test for 30 days followed by an electrochemical corrosion test. Then, human bone cells (MG-63) are cultured on corroded samples and the cell viability is determined using MTT assay, in addition to cell attachment examination. The results revealed the formation of a metallic glass composite layer with 78.76% amorphous content. Additionally, the metallic glass composite demonstrated excellent and stable corrosion resistance in PBS over 30 days compared to the substrate. The MTT assay has shown that the cytotoxicity of iron-based metallic glass composite is within the permitted levels according to ISO 10993-5, Part 5 vol 2009. The cells were well attached to the surface besides, showing a healthy growth after 7 days of culture. These results confirm the in vitro biocompatibility of iron-based metallic glass composite coating for biomedical implant applications.
format	Article
author	Ibrahim, Mahmoud Z. Sarhan, A. A. D. Kuo, T. Y. Yusof, Farazila Hamdi, M. Chang, C. P. Lee, T. M. Chien, C. S.
author_facet	Ibrahim, Mahmoud Z. Sarhan, A. A. D. Kuo, T. Y. Yusof, Farazila Hamdi, M. Chang, C. P. Lee, T. M. Chien, C. S.
author_sort	Ibrahim, Mahmoud Z.
title	Evolution of Iron-Based Metallic Glass Composite Coating with Enhanced Corrosion Resistance and Biocompatibility
title_short	Evolution of Iron-Based Metallic Glass Composite Coating with Enhanced Corrosion Resistance and Biocompatibility
title_full	Evolution of Iron-Based Metallic Glass Composite Coating with Enhanced Corrosion Resistance and Biocompatibility
title_fullStr	Evolution of Iron-Based Metallic Glass Composite Coating with Enhanced Corrosion Resistance and Biocompatibility
title_full_unstemmed	Evolution of Iron-Based Metallic Glass Composite Coating with Enhanced Corrosion Resistance and Biocompatibility
title_sort	evolution of iron-based metallic glass composite coating with enhanced corrosion resistance and biocompatibility
publisher	Springer
publishDate	2024
url	http://eprints.um.edu.my/47149/ https://doi.org/10.1007/s13369-023-08406-3
_version_	1821001886674714624
score	13.23648

Evolution of Iron-Based Metallic Glass Composite Coating with Enhanced Corrosion Resistance and Biocompatibility

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