Combined knee osteoarthritis and diabetes is associated with reduced muscle strength, physical inactivity, and poorer quality of life

Objective: This study delves into the intriguing connection between knee osteoarthritis and diabetes in Malaysia. Specifically, the exacerbation of knee osteoarthritis in the presence of diabetes in terms of symptoms, physical performance, physical activity, psychological status, social participatio...

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Main Authors: Seow, Shi Rui, Mat, Sumaiyah, Teoh, Jun Jie, Yusup, Amyra Mohamad, Rajab, Nor Fadilah, Ismail, Intan Safinar, Singh, Devinder Kaur Ajit, Shahar, Suzana, Tan, Maw Pin, Berenbaum, Francis
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Published: Foundation for Rehabilitation Information 2024
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Online Access:http://eprints.um.edu.my/47113/
https://doi.org/10.2340/jrm.v56.39986
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spelling my.um.eprints.471132024-11-28T04:28:29Z http://eprints.um.edu.my/47113/ Combined knee osteoarthritis and diabetes is associated with reduced muscle strength, physical inactivity, and poorer quality of life Seow, Shi Rui Mat, Sumaiyah Teoh, Jun Jie Yusup, Amyra Mohamad Rajab, Nor Fadilah Ismail, Intan Safinar Singh, Devinder Kaur Ajit Shahar, Suzana Tan, Maw Pin Berenbaum, Francis R Medicine (General) Objective: This study delves into the intriguing connection between knee osteoarthritis and diabetes in Malaysia. Specifically, the exacerbation of knee osteoarthritis in the presence of diabetes in terms of symptoms, physical performance, physical activity, psychological status, social participation, and quality of life was discussed. Design: This cross-sectional study recruited adults aged 50 and above by convenient sampling and grouped them into: knee osteoarthritis-diabetes-, knee osteoarthritis+diabetes-, knee osteoarthritisdiabetes+, and knee osteoarthritis+diabetes+. Subjects/Patients: Of 436 recruited participants, 261 (59.8%) participants reported knee osteoarthritis. Methods: Handgrip strength, Timed Up and Go test, 6 Meter Walk Test, and 5 Times Sit to Stand Test were measured using standardized procedures. Six questionnaires were administered for the remaining parameters. Results: Across groups, there were significant differences: 6 Meter Walk Test (p p = 0.024), Timed Up and Go test (p p = 0.020), and 5 Times Sit to Stand Test (p p < 0.001), quality of life (p p = 0.009), and physical activity (p p = 0.036). Knee osteoarthritis+diabetes+ was independently associated with reduced hand- grip strength, 5 Times Sit to Stand Test, quality of life, and physical inactivity after adjustment. Knee osteoarthritis+diabetes- was independently associated with reduced Timed Up and Go test and social isolation. Conclusion: The findings revealed the diabetic knee osteoarthritis subgroup's unique physical and psychosocial features of reduced muscle strength and physical inactivity. Future studies should investigate whether managing metabolic factors, and enhancing physical activity and strength exercises, can reduce knee osteoarthritis symptoms and disease severity. Foundation for Rehabilitation Information 2024 Article PeerReviewed Seow, Shi Rui and Mat, Sumaiyah and Teoh, Jun Jie and Yusup, Amyra Mohamad and Rajab, Nor Fadilah and Ismail, Intan Safinar and Singh, Devinder Kaur Ajit and Shahar, Suzana and Tan, Maw Pin and Berenbaum, Francis (2024) Combined knee osteoarthritis and diabetes is associated with reduced muscle strength, physical inactivity, and poorer quality of life. Journal of Rehabilitation Medicine, 56. jrm39986. ISSN 1650-1977, DOI https://doi.org/10.2340/jrm.v56.39986 <https://doi.org/10.2340/jrm.v56.39986>. https://doi.org/10.2340/jrm.v56.39986 10.2340/jrm.v56.39986
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine (General)
spellingShingle R Medicine (General)
Seow, Shi Rui
Mat, Sumaiyah
Teoh, Jun Jie
Yusup, Amyra Mohamad
Rajab, Nor Fadilah
Ismail, Intan Safinar
Singh, Devinder Kaur Ajit
Shahar, Suzana
Tan, Maw Pin
Berenbaum, Francis
Combined knee osteoarthritis and diabetes is associated with reduced muscle strength, physical inactivity, and poorer quality of life
description Objective: This study delves into the intriguing connection between knee osteoarthritis and diabetes in Malaysia. Specifically, the exacerbation of knee osteoarthritis in the presence of diabetes in terms of symptoms, physical performance, physical activity, psychological status, social participation, and quality of life was discussed. Design: This cross-sectional study recruited adults aged 50 and above by convenient sampling and grouped them into: knee osteoarthritis-diabetes-, knee osteoarthritis+diabetes-, knee osteoarthritisdiabetes+, and knee osteoarthritis+diabetes+. Subjects/Patients: Of 436 recruited participants, 261 (59.8%) participants reported knee osteoarthritis. Methods: Handgrip strength, Timed Up and Go test, 6 Meter Walk Test, and 5 Times Sit to Stand Test were measured using standardized procedures. Six questionnaires were administered for the remaining parameters. Results: Across groups, there were significant differences: 6 Meter Walk Test (p p = 0.024), Timed Up and Go test (p p = 0.020), and 5 Times Sit to Stand Test (p p < 0.001), quality of life (p p = 0.009), and physical activity (p p = 0.036). Knee osteoarthritis+diabetes+ was independently associated with reduced hand- grip strength, 5 Times Sit to Stand Test, quality of life, and physical inactivity after adjustment. Knee osteoarthritis+diabetes- was independently associated with reduced Timed Up and Go test and social isolation. Conclusion: The findings revealed the diabetic knee osteoarthritis subgroup's unique physical and psychosocial features of reduced muscle strength and physical inactivity. Future studies should investigate whether managing metabolic factors, and enhancing physical activity and strength exercises, can reduce knee osteoarthritis symptoms and disease severity.
format Article
author Seow, Shi Rui
Mat, Sumaiyah
Teoh, Jun Jie
Yusup, Amyra Mohamad
Rajab, Nor Fadilah
Ismail, Intan Safinar
Singh, Devinder Kaur Ajit
Shahar, Suzana
Tan, Maw Pin
Berenbaum, Francis
author_facet Seow, Shi Rui
Mat, Sumaiyah
Teoh, Jun Jie
Yusup, Amyra Mohamad
Rajab, Nor Fadilah
Ismail, Intan Safinar
Singh, Devinder Kaur Ajit
Shahar, Suzana
Tan, Maw Pin
Berenbaum, Francis
author_sort Seow, Shi Rui
title Combined knee osteoarthritis and diabetes is associated with reduced muscle strength, physical inactivity, and poorer quality of life
title_short Combined knee osteoarthritis and diabetes is associated with reduced muscle strength, physical inactivity, and poorer quality of life
title_full Combined knee osteoarthritis and diabetes is associated with reduced muscle strength, physical inactivity, and poorer quality of life
title_fullStr Combined knee osteoarthritis and diabetes is associated with reduced muscle strength, physical inactivity, and poorer quality of life
title_full_unstemmed Combined knee osteoarthritis and diabetes is associated with reduced muscle strength, physical inactivity, and poorer quality of life
title_sort combined knee osteoarthritis and diabetes is associated with reduced muscle strength, physical inactivity, and poorer quality of life
publisher Foundation for Rehabilitation Information
publishDate 2024
url http://eprints.um.edu.my/47113/
https://doi.org/10.2340/jrm.v56.39986
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score 13.223943