Secondary metabolites in topical infectious diseases and nanomedicine applications

Topical infection affects nearly one-third of the world's population; it may result from poor sanitation, hygienic conditions and crowded living and working conditions that accelerate the spread of topical infectious diseases. The problems associated with the anti-infective agents are drug resi...

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Main Authors: Sahoo, Ankit, Dwivedi, Khusbu, Almalki, Waleed H., Mandal, Ashok Kumar, Alhamyani, Abdurrahman, Afzal, Obaid, Alfawaz Altamimi, Abdulmalik Saleh, Alruwaili, Nabil K., Yadav, Pradip Kumar, Barkat, Md Abul, Singh, Tanuja, Rahman, Mahfoozur
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Published: Taylor & Francis 2024
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Online Access:http://eprints.um.edu.my/46971/
https://doi.org/10.2217/nnm-2024-0017
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spelling my.um.eprints.469712025-01-13T00:25:52Z http://eprints.um.edu.my/46971/ Secondary metabolites in topical infectious diseases and nanomedicine applications Sahoo, Ankit Dwivedi, Khusbu Almalki, Waleed H. Mandal, Ashok Kumar Alhamyani, Abdurrahman Afzal, Obaid Alfawaz Altamimi, Abdulmalik Saleh Alruwaili, Nabil K. Yadav, Pradip Kumar Barkat, Md Abul Singh, Tanuja Rahman, Mahfoozur R Medicine (General) Topical infection affects nearly one-third of the world's population; it may result from poor sanitation, hygienic conditions and crowded living and working conditions that accelerate the spread of topical infectious diseases. The problems associated with the anti-infective agents are drug resistance and long-term therapy. Secondary metabolites are obtained from plants, microorganisms and animals, but they are metabolized inside the human body. The integration of nanotechnology into secondary metabolites is gaining attention due to their interaction at the subatomic and skin-tissue levels. Hydrogel, liposomes, lipidic nanoparticles, polymeric nanoparticles and metallic nanoparticles are the most suitable carriers for secondary metabolite delivery. Therefore, the present review article extensively discusses the topical applications of nanomedicines for the effective delivery of secondary metabolites. Taylor & Francis 2024-05 Article PeerReviewed Sahoo, Ankit and Dwivedi, Khusbu and Almalki, Waleed H. and Mandal, Ashok Kumar and Alhamyani, Abdurrahman and Afzal, Obaid and Alfawaz Altamimi, Abdulmalik Saleh and Alruwaili, Nabil K. and Yadav, Pradip Kumar and Barkat, Md Abul and Singh, Tanuja and Rahman, Mahfoozur (2024) Secondary metabolites in topical infectious diseases and nanomedicine applications. Nanomedicine, 19 (13). pp. 1191-1215. ISSN 1743-5889, DOI https://doi.org/10.2217/nnm-2024-0017 <https://doi.org/10.2217/nnm-2024-0017>. https://doi.org/10.2217/nnm-2024-0017 10.2217/nnm-2024-0017
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine (General)
spellingShingle R Medicine (General)
Sahoo, Ankit
Dwivedi, Khusbu
Almalki, Waleed H.
Mandal, Ashok Kumar
Alhamyani, Abdurrahman
Afzal, Obaid
Alfawaz Altamimi, Abdulmalik Saleh
Alruwaili, Nabil K.
Yadav, Pradip Kumar
Barkat, Md Abul
Singh, Tanuja
Rahman, Mahfoozur
Secondary metabolites in topical infectious diseases and nanomedicine applications
description Topical infection affects nearly one-third of the world's population; it may result from poor sanitation, hygienic conditions and crowded living and working conditions that accelerate the spread of topical infectious diseases. The problems associated with the anti-infective agents are drug resistance and long-term therapy. Secondary metabolites are obtained from plants, microorganisms and animals, but they are metabolized inside the human body. The integration of nanotechnology into secondary metabolites is gaining attention due to their interaction at the subatomic and skin-tissue levels. Hydrogel, liposomes, lipidic nanoparticles, polymeric nanoparticles and metallic nanoparticles are the most suitable carriers for secondary metabolite delivery. Therefore, the present review article extensively discusses the topical applications of nanomedicines for the effective delivery of secondary metabolites.
format Article
author Sahoo, Ankit
Dwivedi, Khusbu
Almalki, Waleed H.
Mandal, Ashok Kumar
Alhamyani, Abdurrahman
Afzal, Obaid
Alfawaz Altamimi, Abdulmalik Saleh
Alruwaili, Nabil K.
Yadav, Pradip Kumar
Barkat, Md Abul
Singh, Tanuja
Rahman, Mahfoozur
author_facet Sahoo, Ankit
Dwivedi, Khusbu
Almalki, Waleed H.
Mandal, Ashok Kumar
Alhamyani, Abdurrahman
Afzal, Obaid
Alfawaz Altamimi, Abdulmalik Saleh
Alruwaili, Nabil K.
Yadav, Pradip Kumar
Barkat, Md Abul
Singh, Tanuja
Rahman, Mahfoozur
author_sort Sahoo, Ankit
title Secondary metabolites in topical infectious diseases and nanomedicine applications
title_short Secondary metabolites in topical infectious diseases and nanomedicine applications
title_full Secondary metabolites in topical infectious diseases and nanomedicine applications
title_fullStr Secondary metabolites in topical infectious diseases and nanomedicine applications
title_full_unstemmed Secondary metabolites in topical infectious diseases and nanomedicine applications
title_sort secondary metabolites in topical infectious diseases and nanomedicine applications
publisher Taylor & Francis
publishDate 2024
url http://eprints.um.edu.my/46971/
https://doi.org/10.2217/nnm-2024-0017
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score 13.244413