Cover Image

ATG16L1 rs2241880/T300A increases susceptibility to perianal Crohn's disease: An updated meta-analysis on inflammatory bowel disease risk and clinical outcomes

BackgroundATG16L1 plays a fundamental role in the degradative intracellular pathway known as autophagy, being a mediator of inflammation and microbial homeostasis. The variant rs2241880 can diminish these capabilities, potentially contributing to inflammatory bowel disease (IBD) pathogenesis.Objecti...

Full description

Saved in:

Bibliographic Details
Main Authors:	Simovic, Isidora, Hilmi, Ida, Ng, Ruey Terng, Chew, Kee Seang, Wong, Shin Yee, Lee, Way Seah, Riordan, Stephen, Castano-Rodriguez, Natalia
Format:	Article
Published:	John Wiley & Sons Ltd 2024
Subjects:	R Medicine (General) RJ Pediatrics
Online Access:	http://eprints.um.edu.my/46002/
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Genetic variants involved in innate immunity modulate the risk of inflammatory bowel diseases in an understudied Malaysian population
by: Luu, Laurence Don Wai, et al.
Published: (2022)

Principles of management of Perianal Disease
by: Elagili, Faisal
Published: (2023)

Exclusive enteral nutrition is effective and feasible as primary induction and re-induction therapy in Asian children with Crohn's disease
by: Chan, Kok Joo, et al.
Published: (2021)

Association between inflammatory bowel disease gene 5 (IBD5) and interleukin‐23 receptor (IL23R) genetic polymorphisms in Malaysian patients with Crohn's disease
by: Chua, Kek Heng, et al.
Published: (2012)

Genetic polymorphisms of the NOD1,CXCL16,STAT6,TLR4, ATG16LI and IRGM Genesin Malaysia patients with crohn's disease / Ng Jin Guan
by: Ng, Jin Guan
Published: (2014)

Complementary and alternative medicine (CAM) practices and dietary patterns in children with inflammatory bowel disease in Singapore and Malaysia
by: Ong, Fangyi, et al.
Published: (2018)

Asian Organization for Crohn's and Colitis and Asia Pacific Association of Gastroenterology practice recommendations for medical management and monitoring of inflammatory bowel disease in Asia
by: Ran, Zhihua, et al.
Published: (2021)

Association between inflammatory bowel disease gene 5 (IBD5) and interleukin 23 receptor (IL23R) genetic polymorphisms in Malaysian patients with Crohn's disease
by: Chua, K.H., et al.
Published: (2012)

Quality of life in Malaysian children with inflammatory bowel disease: An understudied population
by: Lee, Gin W., et al.
Published: (2022)

Long term efficacy and persistence of biologics therapy in Crohn’s disease in multiracial Asian country
by: Xin Hui, Khoo, et al.
Published: (2023)

Unusual association of diseases/symptoms: Sweet's syndrome in Crohn's colitis
by: Abdullah , Sheikh Anwar, et al.
Published: (2009)

Co-inheritance of variants/mutations in Malaysian patients with Crohn s disease
by: Chua, K.H., et al.
Published: (2012)

Crohn's disease in adults: observations in a multiracial Asian population.
by: Hilmi, I., et al.
Published: (2006)

Perianal abscess caused by melioidosis
by: Abd Aziz, Mohd Fahmi, et al.
Published: (2018)

The use of infliximab in South-east Asian children with severe Crohn's disease
by: Lee, W.S.
Published: (2004)

Ten missteps in the management of inflammatory bowel disease in Asia: An expert report by the Asian Pacific Association of Gastroenterology Working Group on Inflammatory Bowel Disease
by: Ahuja, Vineet, et al.
Published: (2024)

High accuracy of a simplified, practical algorithm in a differentiating Crohn’s disease from Intestinal Tuberculosis
by: hilmi, ida normiha, et al.
Published: (2023)

Identification of NOD2/CARD15 mutations in Malaysian patients with Crohn's disease
by: Chua, K.H., et al.
Published: (2009)

Endoscopy for Crohn’s disease-related strictures: can we finally replace the surgeons?
by: Nik Muhamad Affendi, Nik Arsyad, et al.
Published: (2024)

Prevalence of osteoporosis in Malaysian patients with inflammatory bowel disease
by: Hilmi, S.I., et al.
Published: (2010)

Inflammatory bowel disease: a survey of the epidemiology in Asia
by: Goh, K.L., et al.
Published: (2009)

The role of microbial agents in the pathogenesis of inflammatory bowel disease
by: Faujan, Nur Huda ,, et al.
Published: (2015)

Long term efficacy and persistence of Biologics Therapy in Crohn Disease in Multiracial Asian Country: A real world experience
by: Nik Muhamad Affendi, Nik Arsyad, et al.
Published: (2023)

Epidemiological characteristics of Asian children with inflammatory bowel disease at diagnosis: Insights from an Asian-Pacific multi-centre registry network
by: Huang, James Guoxian, et al.
Published: (2022)

Lack of association between TYK2 and STAT3 genes and Crohn's disease in the Malaysian population
by: Lian, L.H., et al.
Published: (2013)

Lack of association between TYK2 and STAT3 genes and Crohn’s disease in the Malaysian population
by: Lee, W.S., et al.
Published: (2013)

Parallelization of logic regression analysis on SNP-SNP interactions of a Crohn’s disease dataset model
by: Unitsa Sangket,, et al.
Published: (2017)

Efficacy and safety of vedolizumab in Crohn's disease in patients from Asian countries in the GEMINI 2 study
by: Banerjee, Rupa, et al.
Published: (2021)

Mucinous adenocarcinoma arising from chronic perianal fistula
by: Hisham, Raja B., et al.
Published: (2007)

Detection of Streptococcus bovis from hospitalised patients with inflammatory bowel disease
by: Aziz, Zainal Shukri@Abdul
Published: (2005)

Infection dynamics of ATG8 in leishmania: balancing autophagy for therapeutics
by: Vrushali Guhe, et al.
Published: (2022)

Identification of DLG5 and SLC22A5 gene polymorphisms in Malaysian patients with Crohn's disease
by: Chua, K.H., et al.
Published: (2011)

Perianal Merkel cell carcinoma - a rare case report
by: B A, Arifin, et al.
Published: (2022)

Emerging inflammatory bowel disease demographics, phenotype, and treatment in South Asia, South-East Asia, and Middle East: Preliminary findings from the Inflammatory Bowel Disease-Emerging Nations' Consortium
by: Banerjee, Rupa, et al.
Published: (2022)

Extraintestinal manifestation of inflammatory bowel disease in Asian patients: A multinational study
by: Park, Soo-Kyung, et al.
Published: (2021)

Environmental risk factors for inflammatory bowel disease: A case control study in Southeast Asian children
by: Lee, Way S., et al.
Published: (2022)

Perianal mucinous adenocarcinoma diagnosed by histological study of anorectal abscess with fistula
by: Shir, Li Jee, et al.
Published: (2018)

Healing of the perineal wound after proctectomy in Crohn’s disease patients: only preoperative perineal sepsis predicts poor outcome
by: Li, W., et al.
Published: (2017)

Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease.
by: Aldhous, Marian C., et al.
Published: (2010)

Efficacy of probiotics-based interventions as therapy for inflammatory bowel disease: a recent update
by: Selvamani, Shanmugaprakasham, et al.
Published: (2022)