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Mortality and major postoperative complications within 1 year after vascular surgery: a prospective cohort study

INTRODUCTION Patients undergoing vascular procedures are prone to developing postoperative complications affecting their short -term mortality. Prospective reports describing the incidence of long -term complications after vascular surgery are lacking. OBJECTIVES We aimed to describe the incidence o...

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Main Authors: Polok, Kamil, Biccard, Bruce M., Chan, Matthew T. V., Archbold, R. Andrew, Wang, Chew Yin, Sigamani, Alben, Urrutia, Gerard, Cruz, Patricia, Srinathan, Sadeesh K., Szalay, David, Harlock, John, Tittley, Jacques G., Elias, Fadi, Jacka, Michael J., Malaga, German, Berwanger, Otavio, Studzinska, Dorota, Gorka, Jacek, Montes, Felix R., Chow, Clara K., Ackland, Gareth L., Dubois, Luc, Sapsford, Robert J., Williams, Colin, Cortes, Olga L., Devereaux, Philip J., Szczeklik, Wojciech
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Published: Medycyna Praktyczna 2024
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R Medicine (General)
Online Access:http://eprints.um.edu.my/45828/
https://doi.org/10.20452/pamw.16645
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spelling my.um.eprints.458282024-11-12T07:00:20Z http://eprints.um.edu.my/45828/ Mortality and major postoperative complications within 1 year after vascular surgery: a prospective cohort study Polok, Kamil Biccard, Bruce M. Chan, Matthew T. V. Archbold, R. Andrew Wang, Chew Yin Sigamani, Alben Urrutia, Gerard Cruz, Patricia Srinathan, Sadeesh K. Szalay, David Harlock, John Tittley, Jacques G. Elias, Fadi Jacka, Michael J. Malaga, German Berwanger, Otavio Studzinska, Dorota Gorka, Jacek Montes, Felix R. Chow, Clara K. Ackland, Gareth L. Dubois, Luc Sapsford, Robert J. Williams, Colin Cortes, Olga L. Devereaux, Philip J. Szczeklik, Wojciech R Medicine (General) INTRODUCTION Patients undergoing vascular procedures are prone to developing postoperative complications affecting their short -term mortality. Prospective reports describing the incidence of long -term complications after vascular surgery are lacking. OBJECTIVES We aimed to describe the incidence of complications 1 year after vascular surgery and to evaluate an association between myocardial injury after noncardiac surgery (MINS) and 1 -year mortality. PATIENTS AND METHODS This is a substudy of a large prospective cohort study Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION). Recruitment took place in 28 centers across 14 countries from August 2007 to November 2013. We enrolled patients aged 45 years or older undergoing vascular surgery, receiving general or regional anesthesia, and hospitalized for at least 1 night postoperatively. Plasma cardiac troponin T concentration was measured before the surgery and on the first, second, and third postoperative day. The patients or their relatives were contacted 1 year after the procedure to assess the incidence of major postoperative complications. RESULTS We enrolled 2641 patients who underwent vascular surgery, 2534 (95.9%) of whom completed 1 -year follow -up. Their mean (SD) age was 68.2 (9.8) years, and the cohort was predominantly male (77.5%). The most frequent 1 -year complications were myocardial infarction (224/2534, 8.8%), amputation (187/2534, 7.4%), and congestive heart failure (67/2534, 2.6%). The 1 -year mortality rate was 8.8% (223/2534). MINS occurred in 633 patients (24%) and was associated with an increased 1 -year mortality (hazard ratio, 2.82; 95% CI, 2.14-3.72; P <0.001). CONCLUSIONS The incidence of major postoperative complications after vascular surgery is high. The occurrence of MINS is associated with a nearly 3 -fold increase in 1 -year mortality. Medycyna Praktyczna 2024-02 Article PeerReviewed Polok, Kamil and Biccard, Bruce M. and Chan, Matthew T. V. and Archbold, R. Andrew and Wang, Chew Yin and Sigamani, Alben and Urrutia, Gerard and Cruz, Patricia and Srinathan, Sadeesh K. and Szalay, David and Harlock, John and Tittley, Jacques G. and Elias, Fadi and Jacka, Michael J. and Malaga, German and Berwanger, Otavio and Studzinska, Dorota and Gorka, Jacek and Montes, Felix R. and Chow, Clara K. and Ackland, Gareth L. and Dubois, Luc and Sapsford, Robert J. and Williams, Colin and Cortes, Olga L. and Devereaux, Philip J. and Szczeklik, Wojciech (2024) Mortality and major postoperative complications within 1 year after vascular surgery: a prospective cohort study. Polish Archives of Internal Medicine-Polskie Archiwum Medycyny Wewnetrznej, 134 (2). ISSN 0032-3772, DOI https://doi.org/10.20452/pamw.16645 <https://doi.org/10.20452/pamw.16645>. https://doi.org/10.20452/pamw.16645 10.20452/pamw.16645
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine (General)
spellingShingle R Medicine (General)
Polok, Kamil
Biccard, Bruce M.
Chan, Matthew T. V.
Archbold, R. Andrew
Wang, Chew Yin
Sigamani, Alben
Urrutia, Gerard
Cruz, Patricia
Srinathan, Sadeesh K.
Szalay, David
Harlock, John
Tittley, Jacques G.
Elias, Fadi
Jacka, Michael J.
Malaga, German
Berwanger, Otavio
Studzinska, Dorota
Gorka, Jacek
Montes, Felix R.
Chow, Clara K.
Ackland, Gareth L.
Dubois, Luc
Sapsford, Robert J.
Williams, Colin
Cortes, Olga L.
Devereaux, Philip J.
Szczeklik, Wojciech
Mortality and major postoperative complications within 1 year after vascular surgery: a prospective cohort study
description INTRODUCTION Patients undergoing vascular procedures are prone to developing postoperative complications affecting their short -term mortality. Prospective reports describing the incidence of long -term complications after vascular surgery are lacking. OBJECTIVES We aimed to describe the incidence of complications 1 year after vascular surgery and to evaluate an association between myocardial injury after noncardiac surgery (MINS) and 1 -year mortality. PATIENTS AND METHODS This is a substudy of a large prospective cohort study Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION). Recruitment took place in 28 centers across 14 countries from August 2007 to November 2013. We enrolled patients aged 45 years or older undergoing vascular surgery, receiving general or regional anesthesia, and hospitalized for at least 1 night postoperatively. Plasma cardiac troponin T concentration was measured before the surgery and on the first, second, and third postoperative day. The patients or their relatives were contacted 1 year after the procedure to assess the incidence of major postoperative complications. RESULTS We enrolled 2641 patients who underwent vascular surgery, 2534 (95.9%) of whom completed 1 -year follow -up. Their mean (SD) age was 68.2 (9.8) years, and the cohort was predominantly male (77.5%). The most frequent 1 -year complications were myocardial infarction (224/2534, 8.8%), amputation (187/2534, 7.4%), and congestive heart failure (67/2534, 2.6%). The 1 -year mortality rate was 8.8% (223/2534). MINS occurred in 633 patients (24%) and was associated with an increased 1 -year mortality (hazard ratio, 2.82; 95% CI, 2.14-3.72; P <0.001). CONCLUSIONS The incidence of major postoperative complications after vascular surgery is high. The occurrence of MINS is associated with a nearly 3 -fold increase in 1 -year mortality.
format Article
author Polok, Kamil
Biccard, Bruce M.
Chan, Matthew T. V.
Archbold, R. Andrew
Wang, Chew Yin
Sigamani, Alben
Urrutia, Gerard
Cruz, Patricia
Srinathan, Sadeesh K.
Szalay, David
Harlock, John
Tittley, Jacques G.
Elias, Fadi
Jacka, Michael J.
Malaga, German
Berwanger, Otavio
Studzinska, Dorota
Gorka, Jacek
Montes, Felix R.
Chow, Clara K.
Ackland, Gareth L.
Dubois, Luc
Sapsford, Robert J.
Williams, Colin
Cortes, Olga L.
Devereaux, Philip J.
Szczeklik, Wojciech
author_facet Polok, Kamil
Biccard, Bruce M.
Chan, Matthew T. V.
Archbold, R. Andrew
Wang, Chew Yin
Sigamani, Alben
Urrutia, Gerard
Cruz, Patricia
Srinathan, Sadeesh K.
Szalay, David
Harlock, John
Tittley, Jacques G.
Elias, Fadi
Jacka, Michael J.
Malaga, German
Berwanger, Otavio
Studzinska, Dorota
Gorka, Jacek
Montes, Felix R.
Chow, Clara K.
Ackland, Gareth L.
Dubois, Luc
Sapsford, Robert J.
Williams, Colin
Cortes, Olga L.
Devereaux, Philip J.
Szczeklik, Wojciech
author_sort Polok, Kamil
title Mortality and major postoperative complications within 1 year after vascular surgery: a prospective cohort study
title_short Mortality and major postoperative complications within 1 year after vascular surgery: a prospective cohort study
title_full Mortality and major postoperative complications within 1 year after vascular surgery: a prospective cohort study
title_fullStr Mortality and major postoperative complications within 1 year after vascular surgery: a prospective cohort study
title_full_unstemmed Mortality and major postoperative complications within 1 year after vascular surgery: a prospective cohort study
title_sort mortality and major postoperative complications within 1 year after vascular surgery: a prospective cohort study
publisher Medycyna Praktyczna
publishDate 2024
url http://eprints.um.edu.my/45828/
https://doi.org/10.20452/pamw.16645
_version_ 1816130464678674432
score 13.244413

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