A physiological approach to renal clearance: From premature neonates to adults

AimsWe propose using glomerular filtration rate (GFR) as the physiological basis for distinguishing components of renal clearance.MethodsGentamicin, amikacin and vancomycin are thought to be predominantly excreted by the kidneys. A mixed-effects joint model of the pharmacokinetics of these drugs was...

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Main Authors: Holford, Nick, O'Hanlon, Conor J., Allegaert, Karel, Anderson, Brian, Falcao, Amilcar, Simon, Nicolas, Lo, Yoke-Lin, Thomson, Alison H., Sherwin, Catherine M., Jacqz-Aigrain, Evelyne, Llanos-Paez, Carolina, Hennig, Stefanie, Mockus, Linas, Kirkpatrick, Carl
格式: Article
出版: Wiley 2024
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在线阅读:http://eprints.um.edu.my/45774/
https://doi.org/10.1111/bcp.15978
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