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From fever to action: diagnosis, treatment, and prevention of acute undifferentiated febrile illnesses

Acute Undifferentiated Febrile Illness (AUFI) presents a clinical challenge, often characterized by sudden fever, non-specific symptoms, and potential life-threatening implications. This review highlights the global prevalence, types, challenges, and implications of AUFI, especially in tropical and...

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Main Author: Barathan, Muttiah
Format: Article
Published: Oxford University Press 2024
Subjects:
QR Microbiology
QR180 Immunology
QR355 Virology
R Medicine (General)
Online Access:http://eprints.um.edu.my/45650/
https://doi.org/10.1093/femspd/ftae006
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spelling my.um.eprints.456502024-11-07T06:25:00Z http://eprints.um.edu.my/45650/ From fever to action: diagnosis, treatment, and prevention of acute undifferentiated febrile illnesses Barathan, Muttiah QR Microbiology QR180 Immunology QR355 Virology R Medicine (General) Acute Undifferentiated Febrile Illness (AUFI) presents a clinical challenge, often characterized by sudden fever, non-specific symptoms, and potential life-threatening implications. This review highlights the global prevalence, types, challenges, and implications of AUFI, especially in tropical and subtropical regions where infectious diseases thrive. It delves into the difficulties in diagnosis, prevalence rates, regional variations, and potential causes, ranging from bacterial and viral infections to zoonotic diseases. Furthermore, it explores treatment strategies, preventive measures, and the critical role of the One Health approach in addressing AUFI. The paper also addresses the emerging zoonotic risks and ongoing outbreaks, including COVID-19, Rickettsia spp., and other novel pathogens, emphasizing their impact on AUFI diagnosis and management. Challenges in resource-limited settings are analyzed, highlighting the need for bolstered healthcare infrastructure, enhanced diagnostics, and collaborative One Health strategies. Amidst the complexity of emerging zoonotic threats, this review underscores the urgency for a multifaceted approach to mitigate the growing burden of AUFI, ensuring early diagnosis, appropriate treatment, and effective prevention strategies. Unveiling Acute Undifferentiated Febrile Illness: Global Prevalence, Challenges, and One Health Strategies for Emerging Zoonotic Threats in Resource-Limited Settings. Oxford University Press 2024-02 Article PeerReviewed Barathan, Muttiah (2024) From fever to action: diagnosis, treatment, and prevention of acute undifferentiated febrile illnesses. Pathogens and Disease, 82. ftae006. ISSN 2049-632X, DOI https://doi.org/10.1093/femspd/ftae006 <https://doi.org/10.1093/femspd/ftae006>. https://doi.org/10.1093/femspd/ftae006 10.1093/femspd/ftae006
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic QR Microbiology
QR180 Immunology
QR355 Virology
R Medicine (General)
spellingShingle QR Microbiology
QR180 Immunology
QR355 Virology
R Medicine (General)
Barathan, Muttiah
From fever to action: diagnosis, treatment, and prevention of acute undifferentiated febrile illnesses
description Acute Undifferentiated Febrile Illness (AUFI) presents a clinical challenge, often characterized by sudden fever, non-specific symptoms, and potential life-threatening implications. This review highlights the global prevalence, types, challenges, and implications of AUFI, especially in tropical and subtropical regions where infectious diseases thrive. It delves into the difficulties in diagnosis, prevalence rates, regional variations, and potential causes, ranging from bacterial and viral infections to zoonotic diseases. Furthermore, it explores treatment strategies, preventive measures, and the critical role of the One Health approach in addressing AUFI. The paper also addresses the emerging zoonotic risks and ongoing outbreaks, including COVID-19, Rickettsia spp., and other novel pathogens, emphasizing their impact on AUFI diagnosis and management. Challenges in resource-limited settings are analyzed, highlighting the need for bolstered healthcare infrastructure, enhanced diagnostics, and collaborative One Health strategies. Amidst the complexity of emerging zoonotic threats, this review underscores the urgency for a multifaceted approach to mitigate the growing burden of AUFI, ensuring early diagnosis, appropriate treatment, and effective prevention strategies. Unveiling Acute Undifferentiated Febrile Illness: Global Prevalence, Challenges, and One Health Strategies for Emerging Zoonotic Threats in Resource-Limited Settings.
format Article
author Barathan, Muttiah
author_facet Barathan, Muttiah
author_sort Barathan, Muttiah
title From fever to action: diagnosis, treatment, and prevention of acute undifferentiated febrile illnesses
title_short From fever to action: diagnosis, treatment, and prevention of acute undifferentiated febrile illnesses
title_full From fever to action: diagnosis, treatment, and prevention of acute undifferentiated febrile illnesses
title_fullStr From fever to action: diagnosis, treatment, and prevention of acute undifferentiated febrile illnesses
title_full_unstemmed From fever to action: diagnosis, treatment, and prevention of acute undifferentiated febrile illnesses
title_sort from fever to action: diagnosis, treatment, and prevention of acute undifferentiated febrile illnesses
publisher Oxford University Press
publishDate 2024
url http://eprints.um.edu.my/45650/
https://doi.org/10.1093/femspd/ftae006
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score 13.226497

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