Pharmacological inhibition of endoplasmic reticulum stress mitigates osteoporosis in a mouse model of hindlimb suspension
Hindlimb suspension (HLS) mice exhibit osteoporosis of the hindlimb bones and may be an excellent model to test pharmacological interventions. We investigated the effects of inhibiting endoplasmic reticulum (ER) stress with 4-phenyl butyrate (4-PBA) on the morphology, physicochemical properties, and...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Published: |
Nature Research
2024
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/45552/ https://doi.org/10.1038/s41598-024-54944-7 |
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