Preparation and Preliminary Structure-Activity Relationship Studies of Schwarzinicine A Analogs as Vasorelaxant Agents
Schwarzinicines A-D, a series of alkaloids recently discovered from Ficus schwarzii, exhibit pronounced vasorelaxant activity in rat isolated aorta. Building on this finding, a concise synthesis of schwarzinicines A and B has been reported, allowing further investigations into their biological prope...
Saved in:
Main Authors: | Lee, Fong-Kai, Chan, Nathaniel Jia-Yoong, Krishnan, Premanand, Salam, Dayang Sharyati Datu Abdul, Chee, Xavier Wezen, Muhamad, Azira, Low, Yun Yee, Ting, Kang-Nee, Lim, Kuan-Hon |
---|---|
Format: | Article |
Published: |
American Chemical Society
2024
|
Subjects: | |
Online Access: | http://eprints.um.edu.my/45483/ https://doi.org/10.1021/acs.jnatprod.3c00707 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Concise synthesis of the vasorelaxant alkaloids schwarzinicines A and B
by: Lee, Fong-Kai, et al.
Published: (2022) -
Vasorelaxant effect of a phenylethylamine analogue based on schwarzinicine A an alkaloid isolated from the leaves of Ficus schwarzii
by: Govindaraju, Kayatri, et al.
Published: (2024) -
Effect of acidosis on the mechanism (s) of insulin-induced vasorelaxation in normal Wistar-Kyoto (WKY) rat aorta
by: Subramaniam, G., et al.
Published: (2009) -
Intake of repeatedly heated palm oil causes elevation in blood pressure with impaired vasorelaxation in rats
by: Leong, Xin Fang, et al.
Published: (2009) -
Association of elevated blood pressure and impaired vasorelaxation in experimental Sprague-Dawley rats fed with heated vegetable oil
by: Leong, X.F., et al.
Published: (2010)